Tert-butylhydroquinone attenuates osteoarthritis by protecting chondrocytes and inhibiting macrophage polarization

In vitro effects of macrophages on orthopaedic implant alloys and local release of metallic alloy components

(2020) G. Heise et al.   Bone & Joint Journal

Promising targets and drugs in rheumatoid arthritis

(2020) Xingyan Li et al.   Bone & Joint Research

Synovial fluid fingerprinting in end-stage knee osteoarthritis

(2020) Chethan Jayadev et al.   Bone & Joint Research

Kinsenoside attenuates osteoarthritis by repolarizing macrophages through inactivating NF-κB/MAPK signaling and protecting chondrocytes

(2019) Feng Zhou et al.   Acta Pharmaceutica Sinica B

Role of Norepinephrine in IL-1β-Induced Chondrocyte Dedifferentiation under Physioxia

(2019) Saskia Speichert et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

miR-100-5p-abundant exosomes derived from infrapatellar fat pad MSCs protect articular cartilage and ameliorate gait abnormalities via inhibition of mTOR in osteoarthritis

(2019) Jiangyi Wu et al.   BIOMATERIALS

Multiple intra-articular injections of allogeneic bone marrow-derived stem cells potentially improve knee lesions resulting from surgically induced osteoarthritis

(2019) E. E. Mahmoud et al.   Bone & Joint Journal

MIR-140-5p affects chondrocyte proliferation, apoptosis, and inflammation by targeting HMGB1 in osteoarthritis

(2019) Yingjie Wang et al.   INFLAMMATION RESEARCH

Aucubin Protects Chondrocytes Against IL-1β-Induced Apoptosis In Vitro And Inhibits Osteoarthritis In Mice Model

(2019) Bo-wei Wang et al.   Drug Design Development and Therapy

Precise immunomodulation of the M1 to M2 macrophage transition enhances mesenchymal stem cell osteogenesis and differs by sex

(2019) Karthik Nathan et al.   Bone & Joint Research

Synovial macrophage M1 polarisation exacerbates experimental osteoarthritis partially through R-spondin-2

(2018) Haiyan Zhang et al.   ANNALS OF THE RHEUMATIC DISEASES

Targeting aging for disease modification in osteoarthritis

(2018) John A. Collins et al.   CURRENT OPINION IN RHEUMATOLOGY

Role of Human Macrophage Polarization in Inflammation during Infectious Diseases

(2018) Chiraz Atri et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Tert-butylhydroquinone post-treatment attenuates neonatal hypoxic-ischemic brain damage in rats

(2018) Juan Zhang et al.   NEUROCHEMISTRY INTERNATIONAL

Osteoarthritis year in review 2017: clinical

(2018) A.E. Nelson   OSTEOARTHRITIS AND CARTILAGE

The role of fat and inflammation in the pathogenesis and management of osteoarthritis

(2018) Hema Urban et al.   RHEUMATOLOGY

Inhibition of miR-126 protects chondrocytes from IL-1β induced inflammation via upregulation of Bcl-2

(2018) C. D. Yu et al.   Bone & Joint Research

Parathyroid hormone-related protein exhibits antioxidant features in osteoblastic cells through its N-terminal and osteostatin domains

(2018) S. Portal-Núñez et al.   Bone & Joint Research

Therapeutic Potential and Anti-Amyloidosis Mechanisms of Tert-Butylhydroquinone for Alzheimer's Disease

(2018) Hasina Akhter et al.   JOURNAL OF ALZHEIMERS DISEASE

Nrf2 Activation Provides Atheroprotection in Diabetic Mice Through Concerted Upregulation of Antioxidant, Anti-inflammatory, and Autophagy Mechanisms

(2018) Iolanda Lazaro et al.   Frontiers in Pharmacology

Mechanical stress contributes to osteoarthritis development through the activation of transforming growth factor beta 1 (TGF-β1)

(2018) R-K. Zhang et al.   Bone & Joint Research

Antioxidative Properties and Interconversion of tert-Butylhydroquinone and tert-Butylquinone in Soybean Oils

(2017) Jun Li et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

The gene expression profile of a drug metabolism system and signal transduction pathways in the liver of mice treated with tert-butylhydroquinone or 3-(3'-tert-butyl-4'-hydroxyphenyl)propylthiosulfonate of sodium

(2017) Alexandra B. Shintyapina et al.   PLoS One

Effects of baicalein on IL-1β-induced inflammation and apoptosis in rat articular chondrocytes

(2017) Yue Li et al.   Oncotarget

Sodium Ferulate Protects against Angiotensin II-Induced Cardiac Hypertrophy in Mice by Regulating the MAPK/ERK and JNK Pathways

(2017) Bo Hu et al.   Biomed Research International

Profibrotic Infrapatellar Fat Pad Remodeling Without M1 Macrophage Polarization Precedes Knee Osteoarthritis in Mice With Diet-Induced Obesity

(2017) Erika Barboza et al.   Arthritis & Rheumatology

ROS/oxidative stress signaling in osteoarthritis

(2016) Panagiotis Lepetsos et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Tert-butylhydroquinone attenuates the ethanol-induced apoptosis of and activates the Nrf2 antioxidant defense pathway in H9c2 cardiomyocytes

(2016) XIAOJING SHI et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Osteoarthritis

(2016) Johanne Martel-Pelletier et al.   Nature Reviews Disease Primers

Chondrocyte Apoptosis in the Pathogenesis of Osteoarthritis

(2015) Hyun Hwang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mitochondrial ROS govern the LPS-induced pro-inflammatory response in microglia cells by regulating MAPK and NF-κB pathways

(2015) Junghyung Park et al.   NEUROSCIENCE LETTERS

The antioxidant compound tert-butylhydroquinone activates Akt in myocardium, suppresses apoptosis and ameliorates pressure overload-induced cardiac dysfunction

(2015) Yongtao Zhang et al.   Scientific Reports

tert-Butylhydroquinone (tBHQ) protects hepatocytes against lipotoxicity via inducing autophagy independently of Nrf2 activation

(2013) Songtao Li et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Role of NADPH oxidase/ROS in pro-inflammatory mediators-induced airway and pulmonary diseases

(2012) I-Ta Lee et al.   BIOCHEMICAL PHARMACOLOGY

Osteoarthritis as an inflammatory disease (osteoarthritis is not osteoarthrosis!)

(2012) F. Berenbaum   OSTEOARTHRITIS AND CARTILAGE

Detection of reactive oxygen species (ROS) by the oxidant-sensing probe 2′,7′-dichlorodihydrofluorescein diacetate in the cyanobacterium Anabaena variabilis PCC 7937

(2010) Rajesh P. Rastogi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Role of proinflammatory cytokines in the pathophysiology of osteoarthritis

(2010) Mohit Kapoor et al.   Nature Reviews Rheumatology

Oxidative Stress Inhibits Insulin-like Growth Factor-I Induction of Chondrocyte Proteoglycan Synthesis through Differential Regulation of Phosphatidylinositol 3-Kinase-Akt and MEK-ERK MAPK Signaling Pathways

(2009) Weihong Yin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Primary culture and phenotyping of murine chondrocytes

(2008) Marjolaine Gosset et al.   Nature Protocols