APOE4 genotype exacerbates the depression-like behavior of mice during aging through ATP decline

Astrocytic ApoE reprograms neuronal cholesterol metabolism and histone-acetylation-mediated memory

(2021) Xiaohui Li et al.   NEURON

APOE4 disrupts intracellular lipid homeostasis in human iPSC-derived glia

(2021) Grzegorz Sienski et al.   Science Translational Medicine

Selective removal of astrocytic APOE4 strongly protects against tau-mediated neurodegeneration and decreases synaptic phagocytosis by microglia

(2021) Chao Wang et al.   NEURON

APOE alters glucose flux through central carbon pathways in astrocytes

(2020) Holden C. Williams et al.   NEUROBIOLOGY OF DISEASE

Sex-dependent calcium hyperactivity due to lysosomal-related dysfunction in astrocytes from APOE4 versus APOE3 gene targeted replacement mice

(2020) Raquel Larramona-Arcas et al.   Molecular Neurodegeneration

Altered mitochondrial dynamics and function in APOE4-expressing astrocytes

(2020) Eran Schmukler et al.   Cell Death & Disease

Homozygosity in the APOE 3 Polymorphism Is Associated With Less Depression and Higher Serum Low-Density Lipoprotein in Chinese Elderly Schizophrenics

(2020) Wei Li et al.   Frontiers in Endocrinology

Mitochondria, Microglia, and the Immune System—How Are They Linked in Affective Disorders?

(2019) Carsten Culmsee et al.   Frontiers in Psychiatry

Astrocytic Epoxyeicosatrienoic Acid Signaling in the Medial Prefrontal Cortex Modulates Depressive-like Behaviors

(2019) Wenchao Xiong et al.   JOURNAL OF NEUROSCIENCE

Shared genetic risk factors for depression and stroke

(2019) Fuying Zhao et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Astrocyte, a Promising Target for Mood Disorder Interventions

(2019) Xinyi Zhou et al.   Frontiers in Molecular Neuroscience

The Many Faces of Mitochondrial Dysfunction in Depression: From Pathology to Treatment

(2019) Giuseppe Caruso et al.   Frontiers in Pharmacology

Cognitive dysfunction in major depressive disorder

(2018) Matthew J. Knight et al.   CURRENT OPINION IN PSYCHIATRY

Persistent antidepressant effect of low-dose ketamine and activation in the supplementary motor area and anterior cingulate cortex in treatment-resistant depression: A randomized control study

(2018) Mu-Hong Chen et al.   JOURNAL OF AFFECTIVE DISORDERS

Depression

(2018) Gin S Malhi et al.   LANCET

APOE ε4/ε4 diminishes neurotrophic function of human iPSC-derived astrocytes

(2017) Jing Zhao et al.   HUMAN MOLECULAR GENETICS

Efficacy of Antidepressants for Depression in Alzheimer’s Disease: Systematic Review and Meta-Analysis

(2017) Vasiliki Orgeta et al.   JOURNAL OF ALZHEIMERS DISEASE

Cognitive Impairment in Patients With Depression: Awareness, Assessment, and Management

(2017) Larry Culpepper et al.   JOURNAL OF CLINICAL PSYCHIATRY

Calhm2 governs astrocytic ATP releasing in the development of depression-like behaviors

(2017) M Jun et al.   MOLECULAR PSYCHIATRY

ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy

(2017) Yang Shi et al.   NATURE

Prevalence of Depression in Patients With Mild Cognitive Impairment

(2017) Zahinoor Ismail et al.   JAMA Psychiatry

β-Amyloid, APOE and BDNF Genotype, and Depressive and Anxiety Symptoms in Cognitively Normal Older Women and Men

(2016) Sophie E. Holmes et al.   AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY

Depression as a risk factor for Alzheimer’s disease: Genes, steroids, cytokines and neurogenesis – What do we need to know?

(2016) Joe Herbert et al.   FRONTIERS IN NEUROENDOCRINOLOGY

APOE genotype and stress response - a mini review

(2016) Janina Dose et al.   Lipids in Health and Disease

Early-life stress leads to impaired spatial learning and memory in middle-aged ApoE4-TR mice

(2016) Lan-yan Lin et al.   Molecular Neurodegeneration

Astrocytes in physiological aging and Alzheimer’s disease

(2016) J.J. Rodríguez-Arellano et al.   NEUROSCIENCE

Novel allele-dependent role for APOE in controlling the rate of synapse pruning by astrocytes

(2016) Won-Suk Chung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A 9-Year Prospective Population-Based Study on the Association Between the APOE*E4 Allele and Late-Life Depression in Sweden

(2015) Ingmar Skoog et al.   BIOLOGICAL PSYCHIATRY

Cognitive Behavioral Therapy and Tai Chi Reverse Cellular and Genomic Markers of Inflammation in Late-Life Insomnia: A Randomized Controlled Trial

(2015) Michael R. Irwin et al.   BIOLOGICAL PSYCHIATRY

The Prevalence, Measurement, and Treatment of the Cognitive Dimension/Domain in Major Depressive Disorder

(2015) Roger S. McIntyre et al.   CNS DRUGS

Association between apolipoprotein E gene polymorphism and depression

(2015) Fang Feng et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Neural correlates of change in major depressive disorder anhedonia following open-label ketamine

(2015) Níall Lally et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Genotype-specific effects of Mecp2 loss-of-function on morphology of Layer V pyramidal neurons in heterozygous female Rett syndrome model mice

(2015) Leslie Rietveld et al.   Frontiers in Cellular Neuroscience

Apolipoprotein E: Structure and function in lipid metabolism, neurobiology, and Alzheimer's diseases

(2014) Yadong Huang et al.   NEUROBIOLOGY OF DISEASE

Neural Correlates of Rapid Antidepressant Response to Ketamine in Treatment-Resistant Unipolar Depression: A Preliminary Positron Emission Tomography Study

(2013) Paul J. Carlson et al.   BIOLOGICAL PSYCHIATRY

Astrocyte-derived ATP modulates depressive-like behaviors

(2013) Xiong Cao et al.   NATURE MEDICINE

Mitochondrial dysfunction, oxidative stress, and major depressive disorder

(2013) Edward Tobe   Neuropsychiatric Disease and Treatment

Epigenetic regulation of Arc and c-Fos in the hippocampus after acute electroconvulsive stimulation in the rat

(2012) Mads Dyrvig et al.   BRAIN RESEARCH BULLETIN

Highlighting the versatility of the tracerlab synthesis modules. Part 1: fully automated production of [18F]labelled radiopharmaceuticals using a Tracerlab FXFN

(2011) Xia Shao et al.   JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

Circadian Regulation of ATP Release in Astrocytes

(2011) L. Marpegan et al.   JOURNAL OF NEUROSCIENCE

Baseline Brain Metabolism in Resistant Depression and Response to Transcranial Magnetic Stimulation

(2011) Marie-Laure Paillère Martinot et al.   NEUROPSYCHOPHARMACOLOGY

Interactions Between Age, Stress and Insulin on Cognition: Implications for Alzheimer's Disease

(2010) Maite Solas et al.   NEUROPSYCHOPHARMACOLOGY

Resolving the relationship between ApolipoproteinE and depression

(2009) Michael A. Slifer et al.   NEUROSCIENCE LETTERS

A multilevel analysis of the influence of Apolipoprotein E genotypes on depressive symptoms in late-life moderated by the environment

(2007) Yung-Chieh Yen et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY