CRISPR/Cas9 delivery by NIR-responsive biomimetic nanoparticles for targeted HBV therapy

Construction of homologous cancer cell membrane camouflage in a nano-drug delivery system for the treatment of lymphoma

(2021) Qiangqiang Zhao et al.   JOURNAL OF NANOBIOTECHNOLOGY

Targeted Noninvasive Treatment of Choroidal Neovascularization by Hybrid Cell-Membrane-Cloaked Biomimetic Nanoparticles

(2021) Manjing Li et al.   ACS Nano

Multimodal Enzyme Delivery and Therapy Enabled by Cell Membrane-Coated Metal–Organic Framework Nanoparticles

(2020) Jia Zhuang et al.   NANO LETTERS

Hepatitis B virus cccDNA: Formation, regulation and therapeutic potential

(2020) Yuchen Xia et al.   ANTIVIRAL RESEARCH

Genome editing of mutant KRAS through supramolecular polymer-mediated delivery of Cas9 ribonucleoprotein for colorectal cancer therapy

(2020) Tao Wan et al.   JOURNAL OF CONTROLLED RELEASE

Permanent Inactivation of HBV Genomes by CRISPR/Cas9-Mediated Non-cleavage Base Editing

(2020) Yu-Chan Yang et al.   Molecular Therapy-Nucleic Acids

Chlorin e6 and CRISPR-Cas9 dual-loading system with deep penetration for a synergistic tumoral photodynamic-immunotherapy

(2020) Chengli Yang et al.   BIOMATERIALS

Dicoumarol, an NQO1 inhibitor, blocks cccDNA transcription by promoting degradation of HBx

(2020) Sheng-Tao Cheng et al.   JOURNAL OF HEPATOLOGY

Tumor cell membrane-derived nano-Trojan horses encapsulating phototherapy and chemotherapy are accepted by homologous tumor cells

(2020) Yongtai Zhang et al.   Materials Science & Engineering C-Materials for Biological Applications

Hierarchical Self‐assembly of Discrete Metal–Organic Cages into Supramolecular Nanoparticles for Intracellular Protein Delivery

(2020) Ji Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

CRISPR-Cas9 gene editing of hepatitis B virus in chronically infected humanized mice

(2020) Daniel Stone et al.   Molecular Therapy-Methods & Clinical Development

Red blood cell membrane-camouflaged nanoparticles: a novel drug delivery system for antitumor application

(2019) Qing Xia et al.   Acta Pharmaceutica Sinica B

NIR-Triggered Phototherapy and Immunotherapy via an Antigen-Capturing Nanoplatform for Metastatic Cancer Treatment

(2019) Meng Wang et al.   Advanced Science

Cancer Cell Membrane Camouflaged Nanoprobe for Catalytic Ratiometric Photoacoustic Imaging of MicroRNA in Living Mice

(2019) Kai Zhang et al.   ADVANCED MATERIALS

An Upconversion Nanoparticle Enables Near Infrared-Optogenetic Manipulation of the Caenorhabditis elegans Motor Circuit

(2019) Yanxiao Ao et al.   ACS Nano

Small Molecular Inhibitors of DNA Double Strand Break Repair Pathways Increase the ANTI-HBV Activity of CRISPR/Cas9

(2019) A. P. Kostyusheva et al.   MOLECULAR BIOLOGY

Genetically Engineered Cell Membrane Nanovesicles for Oncolytic Adenovirus Delivery: A Versatile Platform for Cancer Virotherapy

(2019) Peng Lv et al.   NANO LETTERS

CRISPR-Cas based targeting of host and viral genes as an antiviral strategy

(2019) Lulia Koujah et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Fast and Efficient CRISPR/Cas9 Genome Editing In Vivo Enabled by Bioreducible Lipid and Messenger RNA Nanoparticles

(2019) Ji Liu et al.   ADVANCED MATERIALS

Therapeutic strategies for hepatitis B virus infection: towards a cure

(2019) Gregory C. Fanning et al.   NATURE REVIEWS DRUG DISCOVERY

Super-efficient in Vivo Two-Photon Photodynamic Therapy with a Gold Nanocluster as a Type I Photosensitizer

(2019) Rongcheng Han et al.   ACS Nano

A Photolabile Semiconducting Polymer Nanotransducer for Near-Infrared Regulation of CRISPR/Cas9 Gene Editing

(2019) Yan Lyu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Multiple Origins and Specific Evolution of CRISPR/Cas9 Systems in Minimal Bacteria (Mollicutes)

(2019) Thomas Ipoutcha et al.   Frontiers in Microbiology

Degradable Calcium Phosphate-Coated Upconversion Nanoparticles for Highly Efficient Chemo-Photodynamic Therapy

(2019) Shikai Liu et al.   ACS Applied Materials & Interfaces

Responsive Assembly of Upconversion Nanoparticles for pH-Activated and Near-Infrared-Triggered Photodynamic Therapy of Deep Tumors

(2018) Fangyuan Li et al.   ADVANCED MATERIALS

Graphene oxide-mediated Cas9/sgRNA delivery for efficient genome editing

(2018) Huahua Yue et al.   Nanoscale

One-Vector System for Multiplexed CRISPR/Cas9 against Hepatitis B Virus cccDNA Utilizing High-Capacity Adenoviral Vectors

(2018) Maren Schiwon et al.   Molecular Therapy-Nucleic Acids

Leutusome: A Biomimetic Nanoplatform Integrating Plasma Membrane Components of Leukocytes and Tumor Cells for Remarkably Enhanced Solid Tumor Homing

(2018) Hongliang He et al.   NANO LETTERS

Treatment of autosomal dominant hearing loss by in vivo delivery of genome editing agents

(2017) Xue Gao et al.   NATURE

The gRNA-miRNA-gRNA Ternary Cassette Combining CRISPR/Cas9 with RNAi Approach Strongly Inhibits Hepatitis B Virus Replication

(2017) Jie Wang et al.   Theranostics

A Nano-In-Micro System for Enhanced Stem Cell Therapy of Ischemic Diseases

(2017) Hai Wang et al.   ACS Central Science

Nanoparticle delivery of Cas9 ribonucleoprotein and donor DNA in vivo induces homology-directed DNA repair

(2017) Kunwoo Lee et al.   Nature Biomedical Engineering

Artificial Virus Delivers CRISPR-Cas9 System for Genome Editing of Cells in Mice

(2016) Ling Li et al.   ACS Nano

Cancer Cell Membrane-Coated Upconversion Nanoprobes for Highly Specific Tumor Imaging

(2016) Lang Rao et al.   ADVANCED MATERIALS

Aiming for cure in HBV and HDV infection

(2016) Jörg Petersen et al.   JOURNAL OF HEPATOLOGY

Complete Spectrum of CRISPR/Cas9-induced Mutations on HBV cccDNA

(2016) Christoph Seeger et al.   MOLECULAR THERAPY

Preferential Cancer Cell Self-Recognition and Tumor Self-Targeting by Coating Nanoparticles with Homotypic Cancer Cell Membranes

(2016) Jing-Yi Zhu et al.   NANO LETTERS

CRISPR/Cas9 produces anti-hepatitis B virus effect in hepatoma cells and transgenic mouse

(2016) Wei Zhu et al.   VIRUS RESEARCH

Near-Infrared-Sensitive Materials Based on Upconverting Nanoparticles

(2015) Si Wu et al.   ADVANCED MATERIALS

Core-Shell Upconversion Nanoparticle@Metal-Organic Framework Nanoprobes for Luminescent/Magnetic Dual-Mode Targeted Imaging

(2015) Yantao Li et al.   ADVANCED MATERIALS

A novel and sensitive fluorescence immunoassay for the detection of fluoroquinolones in animal-derived foods using upconversion nanoparticles as labels

(2015) Gaoshuang Hu et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Self-Assembled DNA Nanoclews for the Efficient Delivery of CRISPR-Cas9 for Genome Editing

(2015) Wujin Sun et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recurrent AAV2-related insertional mutagenesis in human hepatocellular carcinomas

(2015) Jean-Charles Nault et al.   NATURE GENETICS

Dual gRNAs guided CRISPR/Cas9 system inhibits hepatitis B virus replication

(2015) Jie Wang   WORLD JOURNAL OF GASTROENTEROLOGY

Cell or Cell Membrane-Based Drug Delivery Systems

(2015) Songwei Tan et al.   Theranostics

The CRISPR/Cas9 System Facilitates Clearance of the Intrahepatic HBV Templates In Vivo

(2014) Su-Ru Lin et al.   Molecular Therapy-Nucleic Acids

Targeting Hepatitis B Virus With CRISPR/Cas9

(2014) Christoph Seeger et al.   Molecular Therapy-Nucleic Acids

Bacterial target-specific photocatalyst for the enhancement of antibacterial property to targets

(2013) Min Young Song et al.   APPLIED CATALYSIS B-ENVIRONMENTAL

Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells

(2013) Ophir Shalem et al.   SCIENCE

Photoactive molecules for applications in molecular imaging and cell biology

(2010) Qing Shao et al.   CHEMICAL SOCIETY REVIEWS