Metformin induces muscle atrophy by transcriptional regulation of myostatin via HDAC6 and FoxO3a

Wheel running improves fasting‐induced AMPK signaling in skeletal muscle from tumor‐bearing mice

(2021) Dennis K. Fix et al.   Physiological Reports

Sarcopenia and type 2 diabetes mellitus: a bidirectional relationship

(2019) Jakub Mesinovic et al.   Diabetes Metabolic Syndrome and Obesity-Targets and Therapy

Metformin blunts muscle hypertrophy in response to progressive resistance exercise training in older adults: A randomized, double‐blind, placebo‐controlled, multicenter trial: The MASTERS trial

(2019) R. Grace Walton et al.   AGING CELL

Effect of metformin on myotube BCAA catabolism

(2019) Madison E. Rivera et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Ethical guidelines for publishing in the Journal of Cachexia, Sarcopenia and Muscle : update 2019

(2019) Stephan Haehling et al.   Journal of Cachexia Sarcopenia and Muscle

Effects of metformin on insulin resistance and metabolic disorders in tumor-bearing rats with advanced cachexia

(2018) Flaviane de Fatima Silva et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

The AMPK agonist 5‐aminoimidazole‐4‐carboxamide ribonucleotide (AICAR), but not metformin, prevents inflammation‐associated cachectic muscle wasting

(2018) Derek T Hall et al.   EMBO Molecular Medicine

Aerobic exercise, but not metformin, prevents reduction of muscular performance by AMPk activation in mice on doxorubicin chemotherapy

(2018) Edson A. de Lima et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The Role of AMPK in the Regulation of Skeletal Muscle Size, Hypertrophy, and Regeneration

(2018) David Thomson   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A mouse anti-myostatin antibody increases muscle mass and improves muscle strength and contractility in the mdx mouse model of Duchenne muscular dystrophy and its humanized equivalent, domagrozumab (PF-06252616), increases muscle volume in cynomolgus monkeys

(2017) Michael St. Andre et al.   Skeletal Muscle

AMP-activated kinase α2 deficiency protects mice from denervation-induced skeletal muscle atrophy

(2016) Yuting Guo et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Premature loss of muscle mass and function in type 2 diabetes

(2016) N. Guerrero et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Therapeutic Concentrations of Metformin: A Systematic Review

(2015) Farshad Kajbaf et al.   CLINICAL PHARMACOKINETICS

Genome-wide binding studies reveal DNA binding specificity mechanisms and functional interplay amongst Forkhead transcription factors

(2015) Xi Chen et al.   NUCLEIC ACIDS RESEARCH

Myostatin blockade with a fully human monoclonal antibody induces muscle hypertrophy and reverses muscle atrophy in young and aged mice

(2015) Esther Latres et al.   Skeletal Muscle

Myostatin and the skeletal muscle atrophy and hypertrophy signaling pathways

(2014) J. Rodriguez et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Histone Deacetylase 6 Is a FoxO Transcription Factor-dependent Effector in Skeletal Muscle Atrophy

(2014) Francesca Ratti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanisms regulating skeletal muscle growth and atrophy

(2013) Stefano Schiaffino et al.   FEBS Journal

Patients With Type 2 Diabetes Show a Greater Decline in Muscle Mass, Muscle Strength, and Functional Capacity With Aging

(2013) Marika Leenders et al.   Journal of the American Medical Directors Association

Analysis of In Vitro Insulin-Resistance Models and Their Physiological Relevance to In Vivo Diet-Induced Adipose Insulin Resistance

(2013) Kinyui Alice Lo et al.   Cell Reports

AMP-activated protein kinase stimulates myostatin expression in C2C12 cells

(2012) Arun K. Das et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cellular and molecular mechanisms of muscle atrophy

(2012) P. Bonaldo et al.   Disease Models & Mechanisms

Molecular and cellular mechanisms of skeletal muscle atrophy: an update

(2012) Alessandro Fanzani et al.   Journal of Cachexia Sarcopenia and Muscle

Class IIa Histone Deacetylases Are Hormone-Activated Regulators of FOXO and Mammalian Glucose Homeostasis

(2011) Maria M. Mihaylova et al.   CELL

AMPK promotes skeletal muscle autophagy through activation of forkhead FoxO3a and interaction with Ulk1

(2011) Anthony MJ Sanchez et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Metformin, Independent of AMPK, Inhibits mTORC1 in a Rag GTPase-Dependent Manner

(2010) Adem Kalender et al.   Cell Metabolism