Leiodermatolide, a novel marine natural product, has potent cytotoxic and antimitotic activity against cancer cells, appears to affect microtubule dynamics, and exhibits antitumor activity

Synthesis of triazoloquinazolinone based compounds as tubulin polymerization inhibitors and vascular disrupting agents

(2016) Mohsine Driowya et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Recent Advances in chemistry and pharmacology of 2-methoxyestradiol: An anticancer investigational drug

(2016) B. Sathish Kumar et al.   STEROIDS

Total Synthesis of the Antimitotic Marine Macrolide (−)-Leiodermatolide

(2014) Ian Paterson et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis, Molecular Editing, and Biological Assessment of the Potent Cytotoxin Leiodermatolide

(2014) Damien Mailhol et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Increased Survival in Pancreatic Cancer with nab-Paclitaxel plus Gemcitabine

(2013) Daniel D. Von Hoff et al.   NEW ENGLAND JOURNAL OF MEDICINE

STX140, but Not Paclitaxel, Inhibits Mammary Tumour Initiation and Progression in C3(1)/SV40 T/t-Antigen Transgenic Mice

(2013) Florence Meyer-Losic et al.   PLoS One

Divergent Total Synthesis of the Antimitotic Agent Leiodermatolide

(2012) Jens Willwacher et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Let's huddle to prevent a muddle: centrosome declustering as an attractive anticancer strategy

(2012) A Ogden et al.   CELL DEATH AND DIFFERENTIATION

Leiodermatolide, a Potent Antimitotic Macrolide from the Marine Sponge Leiodermatium sp.

(2011) Ian Paterson et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Microtubule-binding agents: a dynamic field of cancer therapeutics

(2010) Charles Dumontet et al.   NATURE REVIEWS DRUG DISCOVERY

Selective cytotoxic activity of the marine-derived batzelline compounds against pancreatic cancer cell lines

(2009) Esther A. Guzmán et al.   ANTI-CANCER DRUGS

Taccalonolides: Novel microtubule stabilizers with clinical potential

(2009) April L. Risinger et al.   CANCER LETTERS

Tubulin-Interactive Natural Products as Anticancer Agents(1)

(2009) David G. I. Kingston   JOURNAL OF NATURAL PRODUCTS