Growing tumors induce a local STING dependent Type I IFN response in dendritic cells

Cyclooxygenase-Dependent Tumor Growth through Evasion of Immunity

(2015) Santiago Zelenay et al.   CELL

The lack of type I interferon induces neutrophil-mediated pre-metastatic niche formation in the mouse lung

(2015) Ching-Fang Wu et al.   INTERNATIONAL JOURNAL OF CANCER

STING-Dependent Cytosolic DNA Sensing Mediates Innate Immune Recognition of Immunogenic Tumors

(2014) Seng-Ryong Woo et al.   IMMUNITY

STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors

(2014) Liufu Deng et al.   IMMUNITY

Concomitant TLR/RLH Signaling of Radioresistant and Radiosensitive Cells Is Essential for Protection against Vesicular Stomatitis Virus Infection

(2014) Julia Spanier et al.   JOURNAL OF IMMUNOLOGY

The cGAS-cGAMP-STING Pathway of Cytosolic DNA Sensing and Signaling

(2014) Xin Cai et al.   MOLECULAR CELL

Immune Cell-Poor Melanomas Benefit from PD-1 Blockade after Targeted Type I IFN Activation

(2014) T. Bald et al.   Cancer Discovery

Direct effect of dsRNA mimetics on cancer cells induces endogenous IFN-β production capable of improving dendritic cell function

(2013) Gerardo Gatti et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Immune Sensing of DNA

(2013) Søren R. Paludan et al.   IMMUNITY

CXCR2-mediated tumor-associated neutrophil recruitment is regulated by IFN-β

(2013) J. Jablonska et al.   INTERNATIONAL JOURNAL OF CANCER

Immunomodulatory Effects of Interferons in Malignancies

(2013) Joseph Bekisz et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Cell intrinsic immunity spreads to bystander cells via the intercellular transfer of cGAMP

(2013) Andrea Ablasser et al.   NATURE

Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity

(2013) John W. Schoggins et al.   NATURE

IRF-3, IRF-5, and IRF-7 Coordinately Regulate the Type I IFN Response in Myeloid Dendritic Cells Downstream of MAVS Signaling

(2013) Helen M. Lazear et al.   PLoS Pathogens

Constitutive Type I Interferon Modulates Homeostatic Balance through Tonic Signaling

(2012) Daniel J. Gough et al.   IMMUNITY

Type I interferon response and innate immune sensing of cancer

(2012) Mercedes B. Fuertes et al.   TRENDS IN IMMUNOLOGY

Conditional IFNAR1 ablation reveals distinct requirements of Type I IFN signaling for NK cell maturation and tumor surveillance

(2012) Tatsuaki Mizutani et al.   OncoImmunology

Type I IFNs signaling and apoptosis resistance in glioblastoma cells

(2011) Andrea Sgorbissa et al.   APOPTOSIS

Identification and characterization of a loss-of-function human MPYS variant

(2011) L Jin et al.   GENES AND IMMUNITY

Immune Signaling by RIG-I-like Receptors

(2011) Yueh-Ming Loo et al.   IMMUNITY

Host type I IFN signals are required for antitumor CD8+T cell responses through CD8α+dendritic cells

(2011) Mercedes B. Fuertes et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Interferon: Current Status and Future Prospects in Cancer Therapy

(2011) Ben X. Wang et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Production of IFN-β during Listeria monocytogenes Infection Is Restricted to Monocyte/Macrophage Lineage

(2011) Evgenia Solodova et al.   PLoS One

Cytosolic DNA sensors regulating type I interferon induction

(2011) Sinead E. Keating et al.   TRENDS IN IMMUNOLOGY

Neutrophils responsive to endogenous IFN-β regulate tumor angiogenesis and growth in a mouse tumor model

(2010) Jadwiga Jablonska et al.   JOURNAL OF CLINICAL INVESTIGATION

Bacteria-Induced Gap Junctions in Tumors Favor Antigen Cross-Presentation and Antitumor Immunity

(2010) F. Saccheri et al.   Science Translational Medicine

Chemokine Expression in Melanoma Metastases Associated with CD8+ T-Cell Recruitment

(2009) H. Harlin et al.   CANCER RESEARCH

Novel Reporter Mouse Reveals Constitutive and Inflammatory Expression of IFN-  In Vivo

(2009) S. Lienenklaus et al.   JOURNAL OF IMMUNOLOGY