Type I IFNs signaling and apoptosis resistance in glioblastoma cells

The transcriptional code of human IFN-β gene expression

(2010) Ethan Ford et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Identification of USP18 as an Important Regulator of the Susceptibility to IFN-  and Drug-Induced Apoptosis

(2010) H. Potu et al.   CANCER RESEARCH

Circulating markers of angiogenesis, inflammation, and coagulation in patients with glioblastoma

(2010) Gaspar Reynés et al.   JOURNAL OF NEURO-ONCOLOGY

NF-κB activation mediates resistance to IFNβ in MLL-rearranged acute lymphoblastic leukemia

(2010) L Tracey et al.   LEUKEMIA

Resistance to IFN- -Induced Apoptosis Is Linked to a Loss of STAT2

(2010) A. L. Romero-Weaver et al.   MOLECULAR CANCER RESEARCH

A genome-wide RNA interference screen reveals an essential CREB3L2-ATF5-MCL1 survival pathway in malignant glioma with therapeutic implications

(2010) Zhi Sheng et al.   NATURE MEDICINE

IRF-1 transcriptionally upregulates PUMA, which mediates the mitochondrial apoptotic pathway in IRF-1-induced apoptosis in cancer cells

(2009) J Gao et al.   CELL DEATH AND DIFFERENTIATION

Interferon-resistant Daudi Cell Line with a Stat2 Defect Is Resistant to Apoptosis Induced by Chemotherapeutic Agents

(2009) Ziyun Du et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DR5-mediated DISC controls caspase-8 cleavage and initiation of apoptosis in human glioblastomas

(2009) Anita C. Bellail et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Novel Reporter Mouse Reveals Constitutive and Inflammatory Expression of IFN-  In Vivo

(2009) S. Lienenklaus et al.   JOURNAL OF IMMUNOLOGY

Characterization of caspase-dependent and caspase-independent deaths in glioblastoma cells treated with inhibitors of the ubiquitin-proteasome system

(2009) C. Foti et al.   MOLECULAR CANCER THERAPEUTICS

Type I Interferons and Interferon Regulatory Factors Regulate TNF-Related Apoptosis-Inducing Ligand (TRAIL) in HIV-1-Infected Macrophages

(2009) Yunlong Huang et al.   PLoS One

Coupling of Endoplasmic Reticulum Stress to CDDO-Me-Induced Up-regulation of Death Receptor 5 via a CHOP-Dependent Mechanism Involving JNK Activation

(2008) W. Zou et al.   CANCER RESEARCH

IFN-  and Bortezomib Overcome Bcl-2 and Mcl-1 Overexpression in Melanoma Cells by Stimulating the Extrinsic Pathway of Apoptosis

(2008) G. B. Lesinski et al.   CANCER RESEARCH

Arsenic Trioxide Sensitizes Human Glioma Cells, but not Normal Astrocytes, to TRAIL-Induced Apoptosis via CCAAT/Enhancer-Binding Protein Homologous Protein Dependent DR5 Up-regulation

(2008) E. H. Kim et al.   CANCER RESEARCH

Phosphatidylinositol 3-Kinase Inhibition Broadly Sensitizes Glioblastoma Cells to Death Receptor- and Drug-Induced Apoptosis

(2008) D. Opel et al.   CANCER RESEARCH

Critical role for constitutive type I interferon signaling in the prevention of cellular transformation

(2008) Hui-min Chen et al.   CANCER SCIENCE

Inhibition of Aurora B kinase sensitizes a subset of human glioma cells to TRAIL concomitant with induction of TRAIL-R2

(2008) J Li et al.   CELL DEATH AND DIFFERENTIATION

Death receptors as targets for anti-cancer therapy

(2008) Kerstin Papenfuss et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE