Potential of long non-coding RNAs in cancer patients: From biomarkers to therapeutic targets
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Title
Potential of long non-coding RNAs in cancer patients: From biomarkers to therapeutic targets
Authors
Keywords
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Journal
INTERNATIONAL JOURNAL OF CANCER
Volume 140, Issue 9, Pages 1955-1967
Publisher
Wiley
Online
2016-12-07
DOI
10.1002/ijc.30546
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- (2015) Hua-Qiang Zhu et al. Asian Pacific Journal of Cancer Prevention
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- (2015) Xian-Yong Ma et al. BMC GENOMICS
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- (2015) Yilong Yao et al. CANCER LETTERS
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- (2015) L. Kurian et al. CIRCULATION
- Single nucleotide polymorphisms in clinics: Fantasy or reality for cancer?
- (2015) Srilakshmi Srinivasan et al. CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES
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- (2015) Xuelin Zhang et al. JOURNAL OF SURGICAL ONCOLOGY
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- (2015) Yibiao Ye et al. Journal of Translational Medicine
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- (2015) Ting Zhang et al. TUMOR BIOLOGY
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- (2015) M-Z Ma et al. Cell Death & Disease
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- (2015) Yi Shen et al. Oncotarget
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- (2015) Mónica Martínez-Fernández et al. Clinical Epigenetics
- Long Non-Coding RNAs: Challenges for Diagnosis and Therapies
- (2015) Yolanda Sánchez et al. Nucleic Acid Therapeutics
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- (2015) Fubo Wang et al. Oncotarget
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