β-Catenin-NF-κB-CFTR interactions in cholangiocytes regulate inflammation and fibrosis during ductular reaction

Non-canonical Wnt signalling regulates scarring in biliary disease via the planar cell polarity receptors

(2020) D. H. Wilson et al.   Nature Communications

Multidimensional imaging of liver injury repair in mice reveals fundamental role of the ductular reaction

(2020) Kenji Kamimoto et al.   Communications Biology

Hepatic Manifestations of Cystic Fibrosis

(2019) Sasan Sakiani et al.   Clinics in Liver Disease

YAP, but Not RSPO-LGR4/5, Signaling in Biliary Epithelial Cells Promotes a Ductular Reaction in Response to Liver Injury

(2019) Lara Planas-Paz et al.   Cell Stem Cell

Single-Cell Analysis of the Liver Epithelium Reveals Dynamic Heterogeneity and an Essential Role for YAP in Homeostasis and Regeneration

(2019) Brian J. Pepe-Mooney et al.   Cell Stem Cell

Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis

(2019) Josepmaria Argemi et al.   Nature Communications

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Liver Progenitors and Adult Cell Plasticity in Hepatic Injury and Repair: Knowns and Unknowns

(2019) Sungjin Ko et al.   Annual Review of Pathology-Mechanisms of Disease

JASPAR 2020: update of the open-access database of transcription factor binding profiles

(2019) Oriol Fornes et al.   NUCLEIC ACIDS RESEARCH

If It Looks Like a Duct and Acts Like a Duct: On the Role of Reprogrammed Hepatocytes in Cholangiopathies

(2019) Kari Nejak-Bowen   GENE EXPRESSION

Wnt/β-Catenin Signaling in Liver Development, Homeostasis, and Pathobiology

(2018) Jacquelyn O. Russell et al.   Annual Review of Pathology-Mechanisms of Disease

Role of inflammation and proinflammatory cytokines in cholangiocyte pathophysiology

(2018) Claudio Pinto et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Dysregulated bile transporters and impaired tight junctions during chronic liver injury in mice

(2018) Tirthadipa Pradhan-Sundd et al.   GASTROENTEROLOGY

Dual catenin loss in murine liver causes tight junctional deregulation and progressive intrahepatic cholestasis

(2018) Tirthadipa Pradhan-Sundd et al.   HEPATOLOGY

β-Catenin regulation of farnesoid X receptor signaling and bile acid metabolism during murine cholestasis

(2018) Michael D. Thompson et al.   HEPATOLOGY

Hepatocyte-specific β-catenin deletion during severe liver injury provokes cholangiocytes to differentiate into hepatocytes

(2018) Jacquelyn O Russell et al.   HEPATOLOGY

Ductular reaction in liver diseases: pathological mechanisms and translational significances

(2018) Keisaku Sato et al.   HEPATOLOGY

Burden of Liver Diseases in the World

(2018) Sumeet K. Asrani et al.   JOURNAL OF HEPATOLOGY

Ductular reaction cells display an inflammatory profile and recruit neutrophils in alcoholic hepatitis

(2018) Beatriz Aguilar-Bravo et al.   HEPATOLOGY

Biliary bile acids in hepatobiliary injury – What is the link?

(2017) Peter Fickert et al.   JOURNAL OF HEPATOLOGY

Centrilobular ductular reaction correlates with fibrosis stage and fibrosis progression in non-alcoholic steatohepatitis

(2017) Lei Zhao et al.   MODERN PATHOLOGY

Cholangiocytes act as facultative liver stem cells during impaired hepatocyte regeneration

(2017) Alexander Raven et al.   NATURE

The cystic fibrosis transmembrane conductance regulator controls biliary epithelial inflammation and permeability by regulating Src tyrosine kinase activity

(2016) Romina Fiorotto et al.   HEPATOLOGY

Wnt signaling regulates hepatobiliary repair following cholestatic liver injury in mice

(2016) Hirohisa Okabe et al.   HEPATOLOGY

Defective CFTR- β-catenin interaction promotes NF-κB nuclear translocation and intestinal inflammation in cystic fibrosis

(2016) Kaisheng Liu et al.   Oncotarget

CCN1 induces hepatic ductular reaction through integrin αvβ5–mediated activation of NF-κB

(2015) Ki-Hyun Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

Resetting the transcription factor network reverses terminal chronic hepatic failure

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∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis

(2015) Sandra Pankow et al.   NATURE

Hepatic progenitor cells of biliary origin with liver repopulation capacity

(2015) Wei-Yu Lu et al.   NATURE CELL BIOLOGY

HISAT: a fast spliced aligner with low memory requirements

(2015) Daehwan Kim et al.   NATURE METHODS

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Trimmomatic: a flexible trimmer for Illumina sequence data

(2014) Anthony M. Bolger et al.   BIOINFORMATICS

Beta-catenin-NF-κB interactions in murine hepatocytes: A complex to die for

(2012) Kari Nejak-Bowen et al.   HEPATOLOGY

The dynamic biliary epithelia: Molecules, pathways, and disease

(2012) Steven P. O’Hara et al.   JOURNAL OF HEPATOLOGY

NF-κB in the liver—linking injury, fibrosis and hepatocellular carcinoma

(2011) Tom Luedde et al.   Nature Reviews Gastroenterology & Hepatology

Beta-Catenin Activation Promotes Liver Regeneration after Acetaminophen-Induced Injury

(2009) Udayan Apte et al.   AMERICAN JOURNAL OF PATHOLOGY

Liver-Specific β-Catenin Knockout Mice Exhibit Defective Bile Acid and Cholesterol Homeostasis and Increased Susceptibility to Diet-Induced Steatohepatitis

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Role of N-linked oligosaccharides in the biosynthetic processing of the cystic fibrosis membrane conductance regulator

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