Spatially distributed infection increases viral load in a computational model of SARS-CoV-2 lung infection

Early induction of functional SARS-CoV-2 specific T cells associates with rapid viral clearance and mild disease in COVID-19 patients

(2021) Anthony T. Tan et al.   Cell Reports

Modeling SARS-CoV-2 viral kinetics and association with mortality in hospitalized patients from the French COVID cohort

(2021) Nadège Néant et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Generalized chest CT and lab curves throughout the course of COVID-19

(2021) Michael T. Kassin et al.   Scientific Reports

A quantitative model used to compare within-host SARS-CoV-2, MERS-CoV, and SARS-CoV dynamics provides insights into the pathogenesis and treatment of SARS-CoV-2

(2021) Kwang Su Kim et al.   PLOS BIOLOGY

High infectiousness immediately before COVID-19 symptom onset highlights the importance of continued contact tracing

(2021) William Stephen Hart et al.   eLife

Estimation of the incubation period of COVID-19 using viral load data

(2021) Keisuke Ejima et al.   Epidemics

Seroconversion and fever are dose-dependent in a nonhuman primate model of inhalational COVID-19

(2021) Paul A. Dabisch et al.   PLoS Pathogens

Clinically Applicable AI System for Accurate Diagnosis, Quantitative Measurements, and Prognosis of COVID-19 Pneumonia Using Computed Tomography

(2020) Kang Zhang et al.   CELL

Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals

(2020) Alba Grifoni et al.   CELL

Prevalence of comorbidities and its effects in patients infected with SARS-CoV-2: a systematic review and meta-analysis

(2020) Jing Yang et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Mathematical modeling of interaction between innate and adaptive immune responses in COVID‐19 and implications for viral pathogenesis

(2020) Sean Quan Du et al.   JOURNAL OF MEDICAL VIROLOGY

Viral and host factors related to the clinical outcome of COVID-19

(2020) Xiaonan Zhang et al.   NATURE

A mathematical model describing the localization and spread of influenza A virus infection within the human respiratory tract

(2020) Christian Quirouette et al.   PLoS Computational Biology

Inoculum at the time of SARS-CoV-2 exposure and risk of disease severity

(2020) María Pilar Guallar et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Masks Do More Than Protect Others During COVID-19: Reducing the Inoculum of SARS-CoV-2 to Protect the Wearer

(2020) Monica Gandhi et al.   JOURNAL OF GENERAL INTERNAL MEDICINE

Longitudinal analyses reveal immunological misfiring in severe COVID-19

(2020) Carolina Lucas et al.   NATURE

A stochastic agent-based model of the SARS-CoV-2 epidemic in France

(2020) Nicolas Hoertel et al.   NATURE MEDICINE

Evidence for transmission of COVID-19 prior to symptom onset

(2020) Lauren C Tindale et al.   eLife

Antigen-Specific Adaptive Immunity to SARS-CoV-2 in Acute COVID-19 and Associations with Age and Disease Severity

(2020) Carolyn Rydyznski Moderbacher et al.   CELL

Modeling the viral dynamics of SARS-CoV-2 infection

(2020) Sunpeng Wang et al.   MATHEMATICAL BIOSCIENCES

Systems biological assessment of immunity to mild versus severe COVID-19 infection in humans

(2020) Prabhu S. Arunachalam et al.   SCIENCE

Potency and timing of antiviral therapy as determinants of duration of SARS-CoV-2 shedding and intensity of inflammatory response

(2020) Ashish Goyal et al.   Science Advances

Abnormal Lung Quantification in Chest CT Images of COVID‐19 Patients with Deep Learning and its Application to Severity Prediction

(2020) Fei Shan et al.   MEDICAL PHYSICS

A modular framework for multiscale, multicellular, spatiotemporal modeling of acute primary viral infection and immune response in epithelial tissues and its application to drug therapy timing and effectiveness

(2020) T. J. Sego et al.   PLoS Computational Biology

Disentangling the dynamical underpinnings of differences in SARS-CoV-2 pathology using within-host ecological models

(2020) C. Jessica E. Metcalf et al.   PLoS Pathogens

Distributed Adaptive Search in T Cells: Lessons From Ants

(2019) Melanie E. Moses et al.   Frontiers in Immunology

Early Induction of Cross-Reactive CD8+ T-Cell Responses in Tonsils After Live-Attenuated Influenza Vaccination in Children

(2019) K G-I Mohn et al.   JOURNAL OF INFECTIOUS DISEASES

Potential killers exposed: tracking endogenous influenza-specific CD8+ T cells

(2018) Rachael Keating et al.   IMMUNOLOGY AND CELL BIOLOGY

ROCK regulates the intermittent mode of interstitial T cell migration in inflamed lungs

(2017) Paulus Mrass et al.   Nature Communications

In Vivo Killing Capacity of Cytotoxic T Cells Is Limited and Involves Dynamic Interactions and T Cell Cooperativity

(2016) Stephan Halle et al.   IMMUNITY

A spatial model of the efficiency of T cell search in the influenza-infected lung

(2016) Drew Levin et al.   JOURNAL OF THEORETICAL BIOLOGY

Persistence and Adaptation in Immunity: T Cells Balance the Extent and Thoroughness of Search

(2016) G. Matthew Fricke et al.   PLoS Computational Biology

CXCR3 Chemokine Receptor Enables Local CD8+ T Cell Migration for the Destruction of Virus-Infected Cells

(2015) Heather D. Hickman et al.   IMMUNITY

Subtle CXCR3-Dependent Chemotaxis of CTLs within Infected Tissue Allows Efficient Target Localization

(2015) S. Ariotti et al.   JOURNAL OF IMMUNOLOGY

Examination of Influenza Specific T Cell Responses after Influenza Virus Challenge in Individuals Vaccinated with MVA-NP+M1 Vaccine

(2013) Timothy J. Powell et al.   PLoS One

Severe Acute Respiratory Syndrome Coronavirus Replication Is Severely Impaired by MG132 due to Proteasome-Independent Inhibition of M-Calpain

(2012) Martha Schneider et al.   JOURNAL OF VIROLOGY

Generalized Lévy walks and the role of chemokines in migration of effector CD8+ T cells

(2012) Tajie H. Harris et al.   NATURE

Higher Level of Replication Efficiency of 2009 (H1N1) Pandemic Influenza Virus than Those of Seasonal and Avian Strains: Kinetics from Epithelial Cell Culture and Computational Modeling

(2010) H. Mitchell et al.   JOURNAL OF VIROLOGY

Quantifying the Early Immune Response and Adaptive Immune Response Kinetics in Mice Infected with Influenza A Virus

(2010) H. Miao et al.   JOURNAL OF VIROLOGY

Stabilized imaging of immune surveillance in the mouse lung

(2010) Mark R Looney et al.   NATURE METHODS

Agent-based modeling of host–pathogen systems: The successes and challenges

(2008) Amy L. Bauer et al.   INFORMATION SCIENCES

Estimating In Vivo Death Rates of Targets due to CD8 T-Cell-Mediated Killing

(2008) V. V. Ganusov et al.   JOURNAL OF VIROLOGY