Physics-based modeling provides predictive understanding of selectively promiscuous substrate binding by Hsp70 chaperones
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Title
Physics-based modeling provides predictive understanding of selectively promiscuous substrate binding by Hsp70 chaperones
Authors
Keywords
Free energy, Electrostatics, DNA structure, Forecasting, Binders, Hydrogen bonding, Protein interactions, Solvation
Journal
PLoS Computational Biology
Volume 17, Issue 11, Pages e1009567
Publisher
Public Library of Science (PLoS)
Online
2021-11-05
DOI
10.1371/journal.pcbi.1009567
References
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Related references
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- (2018) Matthias P. Mayer PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- Recent advances in the structural and mechanistic aspects of Hsp70 molecular chaperones
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- (2014) R. I. Morimoto et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
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- (2014) Michael Zahn et al. PROTEIN AND PEPTIDE LETTERS
- Molecular Chaperone Functions in Protein Folding and Proteostasis
- (2013) Yujin E. Kim et al. Annual Review of Biochemistry
- Structural Studies on the Forward and Reverse Binding Modes of Peptides to the Chaperone DnaK
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- Structure and Dynamics of the ATP-Bound Open Conformation of Hsp70 Chaperones
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- (2011) F. Ulrich Hartl et al. NATURE
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- (2011) Akihiko Arakawa et al. PROTEIN SCIENCE
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- (2011) Maxim V. Shapovalov et al. STRUCTURE
- CHARMM: The biomolecular simulation program
- (2009) B. R. Brooks et al. JOURNAL OF COMPUTATIONAL CHEMISTRY
- Solution conformation of wild-type E. coli Hsp70 (DnaK) chaperone complexed with ADP and substrate
- (2009) E. B. Bertelsen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Accurate Prediction of DnaK-Peptide Binding via Homology Modelling and Experimental Data
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- Allosteric Coupling between the Lid and Interdomain Linker in DnaK Revealed by Inhibitor Binding Studies
- (2008) M. Liebscher et al. JOURNAL OF BACTERIOLOGY
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