Role of Environment and Experimenter in Reproducibility of Behavioral Studies With Laboratory Mice

Biological sex, not reproductive cycle, influences peripheral blood immune cell prevalence in mice

(2021) Jessica A. Breznik et al.   JOURNAL OF PHYSIOLOGY-LONDON

Considering sex as a biological variable will require a global shift in science culture

(2021) Rebecca M. Shansky et al.   NATURE NEUROSCIENCE

Improving culture of care through maximising learning from observations and events: Addressing what is at fault

(2021) Sally Robinson et al.   LABORATORY ANIMALS

Half of top cancer studies fail high-profile reproducibility effort

(2021) Asher Mullard   NATURE

A wake-up call: Sleep physiology and related translational discrepancies in studies of rapid-acting antidepressants

(2021) Okko Alitalo et al.   PROGRESS IN NEUROBIOLOGY

Automated Home-Cage Testing as a Tool to Improve Reproducibility of Behavioral Research?

(2020) Sophie Helene Richter   Frontiers in Neuroscience

Using Bayes factor hypothesis testing in neuroscience to establish evidence of absence

(2020) Christian Keysers et al.   NATURE NEUROSCIENCE

Reproducibility of animal research in light of biological variation

(2020) Bernhard Voelkl et al.   NATURE REVIEWS NEUROSCIENCE

The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research

(2020) Nathalie Percie du Sert et al.   PLOS BIOLOGY

Internal consistency and compatibility of the 3Rs and 3Vs principles for project evaluation of animal research

(2020) Matthias Eggel et al.   LABORATORY ANIMALS

Considerations for Experimental Design of Behavioral Studies Using Model Organisms

(2019)   JOURNAL OF NEUROSCIENCE

Towards large scale automated cage monitoring – Diurnal rhythm and impact of interventions on in-cage activity of C57BL/6J mice recorded 24/7 with a non-disrupting capacitive-based technique

(2019) Karin Pernold et al.   PLoS One

Sleeping through anything: The effects of unpredictable disruptions on mouse sleep, healing, and affect

(2019) Amy Robinson-Junker et al.   PLoS One

Housing mice in the individually ventilated or open cages—Does it matter for behavioral phenotype?

(2019) Johanna Åhlgren et al.   GENES BRAIN AND BEHAVIOR

Are hormones a “female problem” for animal research?

(2019) Rebecca M. Shansky   SCIENCE

Reproducibility via coordinated standardization: a multi-center study in a Shank2 genetic rat model for Autism Spectrum Disorders

(2019) María Arroyo-Araujo et al.   Scientific Reports

Light and the laboratory mouse

(2018) Stuart N. Peirson et al.   JOURNAL OF NEUROSCIENCE METHODS

Between and within laboratory reliability of mouse behaviour recorded in home-cage and open-field

(2018) Lianne Robinson et al.   JOURNAL OF NEUROSCIENCE METHODS

Getting personal with the “reproducibility crisis”: interviews in the animal research community

(2018) Ben G. Fitzpatrick et al.   LAB ANIMAL

Reproducibility and replicability of rodent phenotyping in preclinical studies

(2018) Neri Kafkafi et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Effects of light and dark phase testing on the investigation of behavioural paradigms in mice: Relevance for behavioural neuroscience

(2018) Juliet Richetto et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Reproducible preclinical research—Is embracing variability the answer?

(2018) Natasha A. Karp   PLOS BIOLOGY

Aggression in group-housed laboratory mice: why can't we solve the problem?

(2017) Elin M. Weber et al.   LAB ANIMAL

Systematic heterogenization for better reproducibility in animal experimentation

(2017) S Helene Richter   LAB ANIMAL

PREPARE: guidelines for planning animal research and testing

(2017) Adrian J Smith et al.   LABORATORY ANIMALS

No publication without confirmation

(2017) Jeffrey S. Mogil et al.   NATURE

Prevalence of sexual dimorphism in mammalian phenotypic traits

(2017) Natasha A. Karp et al.   Nature Communications

1,500 scientists lift the lid on reproducibility

(2016) Monya Baker   NATURE

What does research reproducibility mean?

(2016) Steven N. Goodman et al.   Science Translational Medicine

Female rats are not more variable than male rats: a meta-analysis of neuroscience studies

(2016) Jill B. Becker et al.   Biology of Sex Differences

Experimenter effects on behavioral test scores of eight inbred mouse strains under the influence of ethanol

(2014) Martin Bohlen et al.   BEHAVIOURAL BRAIN RESEARCH

Comparison of automated home-cage monitoring systems: Emphasis on feeding behaviour, activity and spatial learning following pharmacological interventions

(2014) Lianne Robinson et al.   JOURNAL OF NEUROSCIENCE METHODS

Olfactory exposure to males, including men, causes stress and related analgesia in rodents

(2014) Robert E Sorge et al.   NATURE METHODS

Female mice liberated for inclusion in neuroscience and biomedical research

(2014) Brian J. Prendergast et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Assessment of mouse anxiety-like behavior in the light–dark box and open-field arena: Role of equipment and procedure

(2014) Natalia Kulesskaya et al.   PHYSIOLOGY & BEHAVIOR

Six red flags for suspect work

(2013) C. Glenn Begley   NATURE

Enhancing reproducibility

(2013)   NATURE METHODS

Behavioural consequences of IVC cages on male and female C57BL/6J mice

(2013) W. Logge et al.   NEUROSCIENCE

A call for transparent reporting to optimize the predictive value of preclinical research

(2012) Story C. Landis et al.   NATURE

Raise standards for preclinical cancer research

(2012) C. Glenn Begley et al.   NATURE

Effects of Spatial and Cognitive Enrichment on Activity Pattern and Learning Performance in Three Strains of Mice in the IntelliMaze

(2011) Alina Codita et al.   BEHAVIOR GENETICS

Finding the right motivation: Genotype-dependent differences in effective reinforcements for spatial learning

(2011) Jiun Youn et al.   BEHAVIOURAL BRAIN RESEARCH

Believe it or not: how much can we rely on published data on potential drug targets?

(2011) Florian Prinz et al.   NATURE REVIEWS DRUG DISCOVERY

Effect of Population Heterogenization on the Reproducibility of Mouse Behavior: A Multi-Laboratory Study

(2011) S. Helene Richter et al.   PLoS One

Consistent behavioral phenotype differences between inbred mouse strains in the IntelliCage

(2010) S. Krackow et al.   GENES BRAIN AND BEHAVIOR

Taming anxiety in laboratory mice

(2010) Jane L Hurst et al.   NATURE METHODS

Troublesome variability in mouse studies

(2009)   NATURE NEUROSCIENCE

Behavioral effects of ventilated micro-environment housing in three inbred mouse strains

(2009) Yann S. Mineur et al.   PHYSIOLOGY & BEHAVIOR

Survey of the Quality of Experimental Design, Statistical Analysis and Reporting of Research Using Animals

(2009) Carol Kilkenny et al.   PLoS One

Reliability, robustness, and reproducibility in mouse behavioral phenotyping: a cross-laboratory study

(2008) Silvia Mandillo et al.   PHYSIOLOGICAL GENOMICS