Functional drug susceptibility testing using single-cell mass predicts treatment outcome in patient-derived cancer neurosphere models

Mechanisms and therapeutic implications of hypermutation in gliomas

(2020) Mehdi Touat et al.   NATURE

MGMT promoter methylation level in newly diagnosed low-grade glioma is a predictor of hypermutation at recurrence

(2020) Radhika Mathur et al.   NEURO-ONCOLOGY

High-throughput dynamic BH3 profiling may quickly and accurately predict effective therapies in solid tumors

(2020) Patrick D. Bhola et al.   Science Signaling

A Multi-center Study on the Reproducibility of Drug-Response Assays in Mammalian Cell Lines

(2019) Mario Niepel et al.   Cell Systems

Rapid and high-precision sizing of single particles using parallel suspended microchannel resonator arrays and deconvolution

(2019) Max A. Stockslager et al.   REVIEW OF SCIENTIFIC INSTRUMENTS

A Patient-Derived Glioblastoma Organoid Model and Biobank Recapitulates Inter- and Intra-tumoral Heterogeneity

(2019) Fadi Jacob et al.   CELL

Ex-vivo sensitivity profiling to guide clinical decision making in acute myeloid leukemia: A pilot study

(2018) Ronan T. Swords et al.   LEUKEMIA RESEARCH

Patient-derived organoids model treatment response of metastatic gastrointestinal cancers

(2018) Georgios Vlachogiannis et al.   SCIENCE

Organoid profiling identifies common responders to chemotherapy in pancreatic cancer

(2018) Hervé Tiriac et al.   Cancer Discovery

Exploring DNA quality of single cells for genome analysis with simultaneous whole-genome amplification

(2018) Christiane Bäumer et al.   Scientific Reports

Estimation of The Percentage of US Patients With Cancer Who Benefit From Genome-Driven Oncology

(2018) John Marquart et al.   JAMA Oncology

MGMT Promoter Methylation Cutoff with Safety Margin for Selecting Glioblastoma Patients into Trials Omitting Temozolomide. A Pooled Analysis of Four Clinical Trials.

(2018) Monika E Hegi et al.   CLINICAL CANCER RESEARCH

Liquid-Biopsy-Based Identification of EGFR T790M Mutation-Mediated Resistance to Afatinib Treatment in Patients with Advanced EGFR Mutation-Positive NSCLC, and Subsequent Response to Osimertinib

(2018) Maximilian J. Hochmair et al.   Targeted Oncology

Microfluidic active loading of single cells enables analysis of complex clinical specimens

(2018) Nicholas L. Calistri et al.   Nature Communications

Analysis of temozolomide resistance in low-grade gliomas using a mechanistic mathematical model

(2017) Edouard Ollier et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Functional precision cancer medicine—moving beyond pure genomics

(2017) Anthony Letai   NATURE MEDICINE

Determining therapeutic susceptibility in multiple myeloma by single-cell mass accumulation

(2017) Arif E. Cetin et al.   Nature Communications

Drug sensitivity of single cancer cells is predicted by changes in mass accumulation rate

(2016) Mark M Stevens et al.   NATURE BIOTECHNOLOGY

High-throughput measurement of single-cell growth rates using serial microfluidic mass sensor arrays

(2016) Nathan Cermak et al.   NATURE BIOTECHNOLOGY

High-speed multiple-mode mass-sensing resolves dynamic nanoscale mass distributions

(2015) Selim Olcum et al.   Nature Communications

A molecular case report

(2013) Molly Kulesz-Martin et al.   CANCER BIOLOGY & THERAPY

Direct observation of mammalian cell growth and size regulation

(2012) Sungmin Son et al.   NATURE METHODS

American Society of Clinical Oncology Clinical Practice Guideline Update on the Use of Chemotherapy Sensitivity and Resistance Assays

(2011) Harold J. Burstein et al.   JOURNAL OF CLINICAL ONCOLOGY

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

(2008) Roger McLendon et al.   NATURE