RNA-DNA hybrids regulate meiotic recombination

RNA polymerase III is required for the repair of DNA double-strand breaks by homologous recombination

(2021) Sijie Liu et al.   CELL

Regulatory R-loops as facilitators of gene expression and genome stability

(2020) Christof Niehrs et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

DNA Helicase Mph1FANCM Ensures Meiotic Recombination between Parental Chromosomes by Dissociating Precocious Displacement Loops

(2020) Rima Sandhu et al.   DEVELOPMENTAL CELL

MEIOK21: a new component of meiotic recombination bridges required for spermatogenesis

(2020) Yongliang Shang et al.   NUCLEIC ACIDS RESEARCH

DNA:RNA hybrids form at DNA double-strand breaks in transcriptionally active loci

(2020) Aldo S. Bader et al.   Cell Death & Disease

METTL3 and N6-Methyladenosine Promote Homologous Recombination-Mediated Repair of DSBs by Modulating DNA-RNA Hybrid Accumulation

(2020) Canfeng Zhang et al.   MOLECULAR CELL

Tyrosine kinase c-Abl couples RNA polymerase II transcription to DNA double-strand breaks

(2019) Kaspar Burger et al.   NUCLEIC ACIDS RESEARCH

R-Loops as Cellular Regulators and Genomic Threats

(2019) Madzia P. Crossley et al.   MOLECULAR CELL

The meiotic-specific Mek1 kinase in budding yeast regulates interhomolog recombination and coordinates meiotic progression with double-strand break repair

(2019) Nancy M. Hollingsworth et al.   CURRENT GENETICS

The DNA damage response acts as a safeguard against harmful DNA–RNA hybrids of different origins

(2019) Sonia Barroso et al.   EMBO REPORTS

Building bridges to move recombination complexes

(2019) Emeline Dubois et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

R Loops: From Physiological to Pathological Roles

(2019) Tatiana García-Muse et al.   CELL

RNase H1 and H2 Are Differentially Regulated to Process RNA-DNA Hybrids

(2019) Arianna Lockhart et al.   Cell Reports

RNase H eliminates R‐loops that disrupt DNA replication but is nonessential for efficient DSB repair

(2018) Hongchang Zhao et al.   EMBO REPORTS

Drosha drives the formation of DNA:RNA hybrids around DNA break sites to facilitate DNA repair

(2018) Wei-Ting Lu et al.   Nature Communications

Senataxin resolves RNA:DNA hybrids forming at DNA double-strand breaks to prevent translocations

(2018) Sarah Cohen et al.   Nature Communications

Human Rad52 Promotes XPG-Mediated R-loop Processing to Initiate Transcription-Associated Homologous Recombination Repair

(2018) Takaaki Yasuhara et al.   CELL

Genome-wide Map of R-Loop-Induced Damage Reveals How a Subset of R-Loops Contributes to Genomic Instability

(2018) Lorenzo Costantino et al.   MOLECULAR CELL

Next-generation sequencing reveals two populations of damage-induced small RNAs at endogenous DNA double-strand breaks

(2018) Franziska Bonath et al.   NUCLEIC ACIDS RESEARCH

ROS-induced R loops trigger a transcription-coupled but BRCA1/2-independent homologous recombination pathway through CSB

(2018) Yaqun Teng et al.   Nature Communications

BRCA2 controls DNA:RNA hybrid level at DSBs by mediating RNase H2 recruitment

(2018) Giuseppina D’Alessandro et al.   Nature Communications

Sae2/CtIP prevents R-loop accumulation in eukaryotic cells

(2018) Nodar Makharashvili et al.   eLife

RAD52 is required for RNA-templated recombination repair in post-mitotic neurons

(2017) Starr Welty et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rad52 Inverse Strand Exchange Drives RNA-Templated DNA Double-Strand Break Repair

(2017) Olga M. Mazina et al.   MOLECULAR CELL

DNA–RNA hybrids: the risks of DNA breakage during transcription

(2017) Andrés Aguilera et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A global view of meiotic double-strand break end resection

(2017) Eleni P. Mimitou et al.   SCIENCE

DNA–RNA hybrids: the risks of DNA breakage during transcription

(2017) Andrés Aguilera et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Aquarius is required for proper CtIP expression and homologous recombination repair

(2017) Ryo Sakasai et al.   Scientific Reports

R-loop: an emerging regulator of chromatin dynamics: Table 1.

(2016) Qais Al-Hadid et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Control of Meiotic Crossovers: From Double-Strand Break Formation to Designation

(2016) Stephen Gray et al.   Annual Review of Genetics

Transient RNA-DNA Hybrids Are Required for Efficient Double-Strand Break Repair

(2016) Corina Ohle et al.   CELL

RNase H enables efficient repair of R-loop induced DNA damage

(2016) Jeremy D Amon et al.   eLife

RPA homologs and ssDNA processing during meiotic recombination

(2015) Jonathan Ribeiro et al.   CHROMOSOMA

DNA damage during the G0/G1 phase triggers RNA-templated, Cockayne syndrome B-dependent homologous recombination

(2015) Leizhen Wei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recombination, Pairing, and Synapsis of Homologs during Meiosis

(2015) Denise Zickler et al.   Cold Spring Harbor Perspectives in Biology

Meiotic Recombination: The Essence of Heredity

(2015) Neil Hunter   Cold Spring Harbor Perspectives in Biology

Reduced Crossover Interference and Increased ZMM-Independent Recombination in the Absence of Tel1/ATM

(2015) Carol M. Anderson et al.   PLoS Genetics

Senataxin controls meiotic silencing through ATR activation and chromatin remodeling

(2015) Abrey J Yeo et al.   Cell Discovery

Self-Organization of Meiotic Recombination Initiation: General Principles and Molecular Pathways

(2014) Scott Keeney et al.   Annual Review of Genetics

Temporospatial Coordination of Meiotic DNA Replication and Recombination via DDK Recruitment to Replisomes

(2014) Hajime Murakami et al.   CELL

A Timeless but Timely Connection between Replication and Recombination

(2014) Valérie Borde et al.   CELL

Topoisomerase II mediates meiotic crossover interference

(2014) Liangran Zhang et al.   NATURE

Transcript-RNA-templated DNA recombination and repair

(2014) Havva Keskin et al.   NATURE

Interference-mediated synaptonemal complex formation with embedded crossover designation

(2014) Liangran Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DNA Strand Exchange and RecA Homologs in Meiosis

(2014) M. Scott Brown et al.   Cold Spring Harbor Perspectives in Biology

The Logic and Mechanism of Homologous Recombination Partner Choice

(2013) Soogil Hong et al.   MOLECULAR CELL

An expanded tool kit for the auxin-inducible degron system in budding yeast

(2013) Magdalena Morawska et al.   YEAST

Senataxin Plays an Essential Role with DNA Damage Response Proteins in Meiotic Recombination and Gene Silencing

(2013) Olivier J. Becherel et al.   PLoS Genetics

The homologous recombination machinery modulates the formation of RNA–DNA hybrids and associated chromosome instability

(2013) Lamia Wahba et al.   eLife

R-loops cause replication impairment and genome instability during meiosis

(2012) Maikel Castellano-Pozo et al.   EMBO REPORTS

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Rad51 Is an Accessory Factor for Dmc1-Mediated Joint Molecule Formation During Meiosis

(2012) V. Cloud et al.   SCIENCE

Spo11-Accessory Proteins Link Double-Strand Break Sites to the Chromosome Axis in Early Meiotic Recombination

(2011) Silvia Panizza et al.   CELL

RNase H and Multiple RNA Biogenesis Factors Cooperate to Prevent RNA:DNA Hybrids from Generating Genome Instability

(2011) Lamia Wahba et al.   MOLECULAR CELL

Yeast Sen1 Helicase Protects the Genome from Transcription-Associated Instability

(2011) Hannah E. Mischo et al.   MOLECULAR CELL

Bidirectional resection of DNA double-strand breaks by Mre11 and Exo1

(2011) Valerie Garcia et al.   NATURE

Sister Cohesion and Structural Axis Components Mediate Homolog Bias of Meiotic Recombination

(2010) Keun P. Kim et al.   CELL

Temporally and Biochemically Distinct Activities of Exo1 during Meiosis: Double-Strand Break Resection and Resolution of Double Holliday Junctions

(2010) Kseniya Zakharyevich et al.   MOLECULAR CELL

Ribonuclease H: the enzymes in eukaryotes

(2009) Susana M. Cerritelli et al.   FEBS Journal

The S-Phase Checkpoint Is Required To Respond to R-Loops Accumulated in THO Mutants

(2009) B. Gomez-Gonzalez et al.   MOLECULAR AND CELLULAR BIOLOGY

Initiation of meiotic chromosome synapsis at centromeres in budding yeast

(2008) T. Tsubouchi et al.   GENES & DEVELOPMENT