NKG2A expression identifies a subset of human Vδ2 T cells exerting the highest antitumor effector functions

HLA-E expression in diffuse glioma: relationship with clinicopathological features and patient survival

(2020) Zhifeng Wu et al.   BMC Neurology

Alpaca (Vicugna pacos), the first nonprimate species with a phosphoantigen-reactive Vγ9Vδ2 T cell subset

(2020) Alina S. Fichtner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fetal public Vγ9Vδ2 T cells expand and gain potent cytotoxic functions early after birth

(2020) Maria Papadopoulou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High CD26 and Low CD94 Expression Identifies an IL-23 Responsive Vδ2+ T Cell Subset with a MAIT Cell-like Transcriptional Profile

(2020) Kathleen M. Wragg et al.   Cell Reports

Targeting NKG2A to elucidate natural killer cell ontogenesis and to develop novel immune-therapeutic strategies in cancer therapy

(2019) Elisa Zaghi et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Immune Checkpoint Inhibitors: Anti-NKG2A Antibodies on Board

(2019) Maria Cristina Mingari et al.   TRENDS IN IMMUNOLOGY

Are human Vδ2pos T cells really resistant to aging and Human Cytomegalovirus infection?

(2019) Joanna Mikulak et al.   EBioMedicine

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

Single-cell trajectories reconstruction, exploration and mapping of omics data with STREAM

(2019) Huidong Chen et al.   Nature Communications

Enriched HLA-E and CD94/NKG2A Interaction Limits Antitumor CD8+ Tumor-Infiltrating T Lymphocyte Responses

(2019) Megat Abd Hamid et al.   Cancer Immunology Research

Translating gammadelta (γδ) T cells and their receptors into cancer cell therapies

(2019) Zsolt Sebestyen et al.   NATURE REVIEWS DRUG DISCOVERY

Monalizumab: inhibiting the novel immune checkpoint NKG2A

(2019) Thorbald van Hall et al.   Journal for ImmunoTherapy of Cancer

Chemotherapy accelerates immune-senescence and functional impairments of Vδ2pos T cells in elderly patients affected by liver metastatic colorectal cancer

(2019) Elena Bruni et al.   Journal for ImmunoTherapy of Cancer

Natural killer cell education in human health and disease

(2018) Jeanette E Boudreau et al.   CURRENT OPINION IN IMMUNOLOGY

NKG2D and its ligands in cancer

(2018) Payal Dhar et al.   CURRENT OPINION IN IMMUNOLOGY

The early expansion of anergic NKG2Apos/CD56dim/CD16neg natural killer cells represents a therapeutic target in haploidentical haematopoietic stem cell transplantation

(2018) Alessandra Roberto et al.   HAEMATOLOGICA

Unconventional T Cell Targets for Cancer Immunotherapy

(2018) Dale I. Godfrey et al.   IMMUNITY

The human Vδ2+ T-cell compartment comprises distinct innate-like Vγ9+ and adaptive Vγ9- subsets

(2018) Martin S. Davey et al.   Nature Communications

The early expansion of anergic NKG2Apos/CD56dim/CD16neg natural killer cells represents a therapeutic target in haploidentical haematopoietic stem cell transplantation

(2018) Alessandra Roberto et al.   HAEMATOLOGICA

CD161 Defines a Functionally Distinct Subset of Pro-Inflammatory Natural Killer Cells

(2018) Ayako Kurioka et al.   Frontiers in Immunology

High-dimensional single cell analysis identifies stem-like cytotoxic CD8+T cells infiltrating human tumors

(2018) Jolanda Brummelman et al.   JOURNAL OF EXPERIMENTAL MEDICINE

NKG2D Ligands–Critical Targets for Cancer Immune Escape and Therapy

(2018) Dominik Schmiedel et al.   Frontiers in Immunology

NKG2A Blockade Potentiates CD8 T Cell Immunity Induced by Cancer Vaccines

(2018) Nadine van Montfoort et al.   CELL

Anti-NKG2A mAb Is a Checkpoint Inhibitor that Promotes Anti-tumor Immunity by Unleashing Both T and NK Cells

(2018) Pascale André et al.   CELL

Mapping of γ/δ T cells reveals Vδ2+ T cells resistance to senescence

(2018) Weili Xu et al.   EBioMedicine

NK cell education via nonclassical MHC and non-MHC ligands

(2016) Yuke He et al.   Cellular & Molecular Immunology

γδ T cells in cancer immunotherapy

(2016) Chang Zou et al.   Oncotarget

Orphan granzymes find a home

(2015) Niels Bovenschen et al.   IMMUNOLOGICAL REVIEWS

SHP-1-mediated inhibitory signals promote responsiveness and anti-tumour functions of natural killer cells

(2014) Charlotte Viant et al.   Nature Communications

Controlling Natural Killer Cell Responses: Integration of Signals for Activation and Inhibition

(2013) Eric O. Long et al.   Annual Review of Immunology

Differentiation and functional regulation of human fetal NK cells

(2013) Martin A. Ivarsson et al.   JOURNAL OF CLINICAL INVESTIGATION

Natural Cytotoxicity Receptors: Broader Expression Patterns and Functions in Innate and Adaptive Immune Cells

(2013) Kelly Hudspeth et al.   Frontiers in Immunology

Tumor cell recognition by γδ T lymphocytes

(2013) Daniel V. Correia et al.   OncoImmunology

Engagement of NKp30 on V 1 T cells induces the production of CCL3, CCL4, and CCL5 and suppresses HIV-1 replication

(2012) K. Hudspeth et al.   BLOOD

Nonclassical NK cell education

(2012) Werner Held   NATURE IMMUNOLOGY

Inhibitory receptors specific for MHC class I educate murine NK cells but not CD8   intestinal intraepithelial T lymphocytes

(2011) S. Taveirne et al.   BLOOD

Differentiation, phenotype, and function of interleukin-17-producing human V 9V 2 T cells

(2011) N. Caccamo et al.   BLOOD

HLA-E/β2 microglobulin overexpression in colorectal cancer is associated with recruitment of inhibitory immune cells and tumor progression

(2011) Céline Bossard et al.   INTERNATIONAL JOURNAL OF CANCER

HLA-E expression by gynecological cancers restrains tumor-infiltrating CD8+ T lymphocytes

(2011) M. Gooden et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Confinement of Activating Receptors at the Plasma Membrane Controls Natural Killer Cell Tolerance

(2011) S. Guia et al.   Science Signaling

NKG2A inhibits NKG2C effector functions of γδ T cells: implications in health and disease

(2010) Daniela F. Angelini et al.   JOURNAL OF LEUKOCYTE BIOLOGY

NK Cell Responsiveness Is Tuned Commensurate with the Number of Inhibitory Receptors for Self-MHC Class I: The Rheostat Model

(2009) N. T. Joncker et al.   JOURNAL OF IMMUNOLOGY

MHC class I-specific inhibitory receptors and their ligands structure diverse human NK-cell repertoires toward a balance of missing self-response

(2008) M. Yawata et al.   BLOOD

Relationship between CD107a expression and cytotoxic activity

(2008) Esin Aktas et al.   CELLULAR IMMUNOLOGY

Acute upregulation of an NKG2D ligand promotes rapid reorganization of a local immune compartment with pleiotropic effects on carcinogenesis

(2008) Jessica Strid et al.   NATURE IMMUNOLOGY

Structural basis for NKG2A/CD94 recognition of HLA-E

(2008) B. K. Kaiser et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA