RBS and Promoter Strengths Determine the Cell-Growth-Dependent Protein Mass Fractions and Their Optimal Synthesis Rates

Coupling of Ribosome Synthesis and Translational Capacity with Cell Growth

(2020) Xiongfeng Dai et al.   TRENDS IN BIOCHEMICAL SCIENCES

General quantitative relations linking cell growth and the cell cycle in Escherichia coli

(2020) Hai Zheng et al.   Nature Microbiology

Characterization and mitigation of gene expression burden in mammalian cells

(2020) Timothy Frei et al.   Nature Communications

Central dogma rates and the trade-off between precision and economy in gene expression

(2019) Jean Hausser et al.   Nature Communications

Modelling and measuring intracellular competition for finite resources during gene expression

(2019) Renana Sabi et al.   Journal of the Royal Society Interface

Absolute quantification of translational regulation and burden using combined sequencing approaches

(2019) Thomas E Gorochowski et al.   Molecular Systems Biology

Growth defects and loss-of-function in synthetic gene circuits

(2019) Evangelos-Marios Nikolados et al.   ACS Synthetic Biology

Circuit-Host Coupling Induces Multifaceted Behavioral Modulations of a Gene Switch

(2018) Andrew E. Blanchard et al.   BIOPHYSICAL JOURNAL

Optimality and sub-optimality in a bacterial growth law

(2017) Benjamin D. Towbin et al.   Nature Communications

Resource Competition Shapes the Response of Genetic Circuits

(2017) Yili Qian et al.   ACS Synthetic Biology

Principles of cellular resource allocation revealed by condition-dependent proteome profiling

(2017) Eyal Metzl-Raz et al.   eLife

A Minimal Model of Ribosome Allocation Dynamics Captures Trade-offs in Expression between Endogenous and Synthetic Genes

(2016) Thomas E. Gorochowski et al.   ACS Synthetic Biology

How fast-growing bacteria robustly tune their ribosome concentration to approximate growth-rate maximization

(2015) Evert Bosdriesz et al.   FEBS Journal

Quantifying cellular capacity identifies gene expression designs with reduced burden

(2015) Francesca Ceroni et al.   NATURE METHODS

Dealing with the genetic load in bacterial synthetic biology circuits: convergences with the Ohm's law

(2015) M. Carbonell-Ballestero et al.   NUCLEIC ACIDS RESEARCH

Mechanistic links between cellular trade-offs, gene expression, and growth

(2015) Andrea Y. Weiße et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MEIGO: an open-source software suite based on metaheuristics for global optimization in systems biology and bioinformatics

(2014) Jose A Egea et al.   BMC BIOINFORMATICS

The Interrelationship between Promoter Strength, Gene Expression, and Growth Rate

(2014) Matthew S. Bienick et al.   PLoS One

Recombinant protein expression in Escherichia coli: advances and challenges

(2014) Germán L. Rosano et al.   Frontiers in Microbiology

Retroactivity Controls the Temporal Dynamics of Gene Transcription

(2013) Shridhar Jayanthi et al.   ACS Synthetic Biology

Contextualizing context for synthetic biology - identifying causes of failure of synthetic biological systems

(2012) Stefano Cardinale et al.   Biotechnology Journal

Synthetic gene circuits for metabolic control: design trade-offs and constraints

(2012) D. A. Oyarzun et al.   Journal of the Royal Society Interface

Interdependence of Cell Growth and Gene Expression: Origins and Consequences

(2010) M. Scott et al.   SCIENCE

BioNumbers—the database of key numbers in molecular and cell biology

(2009) Ron Milo et al.   NUCLEIC ACIDS RESEARCH