CircZNF532 knockdown protects retinal pigment epithelial cells against high glucose‐induced apoptosis and pyroptosis by regulating the miR‐20b‐5p/STAT3 axis

Attenuation of High Glucose-Induced Damage in RPE Cells through p38 MAPK Signaling Pathway Inhibition

(2021) Grazia Maugeri et al.   Frontiers in Pharmacology

Astragalus polysaccharide attenuates metabolic memory-triggered ER stress and apoptosis via regulation of miR-204/SIRT1 axis in retinal pigment epithelial cells

(2020) Qing-Hua Peng et al.   BIOSCIENCE REPORTS

MicroRNA-20b-5p regulates propofol-preconditioning-induced inhibition of autophagy in hypoxia-and-reoxygenation-stimulated endothelial cells

(2020) Wang Zhen et al.   JOURNAL OF BIOSCIENCES

Comprehensive review of ASC structure and function in immune homeostasis and disease

(2020) Ishan Agrawal et al.   MOLECULAR BIOLOGY REPORTS

Physcion 8-O-β-glucopyranoside exerts protective roles in high glucose-induced diabetic retinopathy via regulating lncRNA NORAD/miR-125/STAT3 signalling

(2020) Wencui Wan et al.   Artificial Cells Nanomedicine and Biotechnology

Overexpression of METTL3 attenuates high-glucose induced RPE cell pyroptosis by regulating miR-25-3p/PTEN/Akt signaling cascade through DGCR8

(2020) Xu Zha et al.   Aging-US

Inhibition of hsa_circ_0002570 suppresses high-glucose–induced angiogenesis and inflammation in retinal microvascular endothelial cells through miR-1243/angiomotin axis

(2020) Guodan Liu et al.   CELL STRESS & CHAPERONES

Diabetes Mellitus and Cardiovascular Risk Assessment in Mothers with a History of Gestational Diabetes Mellitus Based on Postpartal Expression Profile of MicroRNAs Associated with Diabetes Mellitus and Cardiovascular and Cerebrovascular Diseases

(2020) Ilona Hromadnikova et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Long non-coding RNA MALAT1 aggravates human retinoblastoma by sponging miR-20b-5p to upregulate STAT3

(2020) Liming Wang et al.   PATHOLOGY RESEARCH AND PRACTICE

circRNA_0084043 contributes to the progression of diabetic retinopathy via sponging miR-140-3p and inducing TGFA gene expression in retinal pigment epithelial cells

(2020) Ying Li et al.   GENE

Circular RNA-ZNF532 regulates diabetes-induced retinal pericyte degeneration and vascular dysfunction

(2020) Qin Jiang et al.   JOURNAL OF CLINICAL INVESTIGATION

Circular RNA COL1A2 promotes angiogenesis via regulating miR-29b/VEGF axis in diabetic retinopathy

(2020) Jing Zou et al.   LIFE SCIENCES

PD-L1-mediated gasdermin C expression switches apoptosis to pyroptosis in cancer cells and facilitates tumour necrosis

(2020) Junwei Hou et al.   NATURE CELL BIOLOGY

Bone marrow mesenchymal stem cells-induced exosomal microRNA-486-3p protects against diabetic retinopathy through TLR4/NF-κB axis repression

(2020) W. Li et al.   JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION

Roles of circular RNAs in diabetic complications: From molecular mechanisms to therapeutic potential

(2020) Ji-Ru Zhang et al.   GENE

High-glucose induces retinal pigment epithelium mitochondrial pathways of apoptosis and inhibits mitophagy by regulating ROS/PINK1/Parkin signal pathway

(2019) Yuanping Zhang et al.   BIOMEDICINE & PHARMACOTHERAPY

NOD-like receptors and inflammasomes: A review of their canonical and non-canonical signaling pathways

(2019) Jaye M. Platnich et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Diabetic retinopathy: Focus on NADPH oxidase and its potential as therapeutic target

(2019) Jing-Jie Peng et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The biogenesis, biology and characterization of circular RNAs

(2019) Lasse S. Kristensen et al.   NATURE REVIEWS GENETICS

Comparison of expression profiling of circular RNAs in vitreous humour between diabetic retinopathy and non-diabetes mellitus patients

(2019) Miao He et al.   ACTA DIABETOLOGICA

miR-7 reduces high glucose induced-damage via HoxB3 and PI3K/AKT/mTOR signaling pathways in retinal pigment epithelial cells

(2019) Zhongyi Yang et al.   CURRENT MOLECULAR MEDICINE

Downregulation of circRNA DMNT3B contributes to diabetic retinal vascular dysfunction through targeting miR-20b-5p and BAMBI

(2019) Ke Zhu et al.   EBioMedicine

Pyroptosis: A new frontier in cancer

(2019) Yuan Fang et al.   BIOMEDICINE & PHARMACOTHERAPY

A new research hot spot: The role of NLRP3 inflammasome activation, a key step in pyroptosis, in diabetes and diabetic complications

(2019) Zi-Wei Yu et al.   LIFE SCIENCES

7,8-Dihydroxyflavone ameliorates high-glucose induced diabetic apoptosis in human retinal pigment epithelial cells by activating TrkB

(2018) Xiaoyi Yu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

MicroRNA-20b-5p inhibits platelet-derived growth factor-induced proliferation of human fetal airway smooth muscle cells by targeting signal transducer and activator of transcription 3

(2018) Jin Tang et al.   BIOMEDICINE & PHARMACOTHERAPY

Dexmedetomidine protects high-glucose induced apoptosis in human retinal pigment epithelial cells through inhibition on p75(NTR)

(2018) Ran Liu et al.   BIOMEDICINE & PHARMACOTHERAPY

MicroRNA

(2018) Thomas X. Lu et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Inflammatory caspase-related pyroptosis: mechanism, regulation and therapeutic potential for inflammatory bowel disease

(2018) Yuan-Yuan Yuan et al.   Gastroenterology Report

Identification of O-GlcNAcylation Modification in Diabetic Retinopathy and Crosstalk with Phosphorylation of STAT3 in Retina Vascular Endothelium Cells

(2018) Chong Xu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Diagnostic and Prognostic Role of Serum miR-20b, miR-17-3p, HOTAIR, and MALAT1 in Diabetic Retinopathy

(2018) Olfat G. Shaker et al.   IUBMB LIFE

Association between microRNAs expression and signaling pathways of inflammatory markers in diabetic retinopathy

(2018) Rana Shafabakhsh et al.   JOURNAL OF CELLULAR PHYSIOLOGY

miR-146a suppresses STAT3/VEGF pathways and reduces apoptosis through IL-6 signaling in primary human retinal microvascular endothelial cells in high glucose conditions

(2017) Eun-Ah Ye et al.   VISION RESEARCH

Insights into circular RNA biology

(2016) Karoline K. Ebbesen et al.   RNA Biology

Diabetic retinopathy

(2016) Tien Y. Wong et al.   Nature Reviews Disease Primers

Diagnosis and Classification of Diabetes Mellitus

(2011)   DIABETES CARE