Neuroprotection of chicoric acid in a mouse model of Parkinson's disease involves gut microbiota and TLR4 signaling pathway

Roflupram exerts neuroprotection via activation of CREB/PGC‐1α signalling in experimental models of Parkinson's disease

(2020) Jiahong Zhong et al.   BRITISH JOURNAL OF PHARMACOLOGY

RNF 152 positively regulates TLR / IL ‐1R signaling by enhancing MyD88 oligomerization

(2020) Mei‐Guang Xiong et al.   EMBO REPORTS

The Link between Gut Dysbiosis and Neuroinflammation in Parkinson’s Disease

(2020) José Fidel Baizabal-Carvallo et al.   NEUROSCIENCE

Abnormal brain structure and behavior in MyD88-deficient mice

(2020) Patricia Schroeder et al.   BRAIN BEHAVIOR AND IMMUNITY

Role of gut-brain axis, gut microbial composition, and probiotic intervention in Alzheimer's disease

(2020) Periyanaina Kesika et al.   LIFE SCIENCES

Parkinson’s Disease — What’s the FUS?

(2020) Joel S. Perlmutter et al.   NEW ENGLAND JOURNAL OF MEDICINE

TNF‐α inhibits GDNF levels in Sertoli cells, through a NF‐κB‐dependent, HES1‐dependent mechanism

(2020) Sara Di Persio et al.   Andrology

The Bioactive Effects of Chicoric Acid As a Functional Food Ingredient

(2019) Ye Peng et al.   JOURNAL OF MEDICINAL FOOD

The role of short-chain fatty acids in microbiota–gut–brain communication

(2019) Boushra Dalile et al.   Nature Reviews Gastroenterology & Hepatology

Ruminococcus gnavus, a member of the human gut microbiome associated with Crohn’s disease, produces an inflammatory polysaccharide

(2019) Matthew T. Henke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Altered Gut Microbiome in Parkinson’s Disease and the Influence of Lipopolysaccharide in a Human α-Synuclein Over-Expressing Mouse Model

(2019) Anastazja M. Gorecki et al.   Frontiers in Neuroscience

Alterations of the gut microbiota with antibiotics protects dopamine neuron loss and improve motor deficits in a pharmacological rodent model of Parkinson's disease

(2019) Dimitri N. Koutzoumis et al.   EXPERIMENTAL NEUROLOGY

Early signs of colonic inflammation, intestinal dysfunction, and olfactory impairments in the rotenone-induced mouse model of Parkinson’s disease

(2018) Lívia H. Morais et al.   BEHAVIOURAL PHARMACOLOGY

Alteration of the fecal microbiota in Chinese patients with Parkinson’s disease

(2018) Yiwei Qian et al.   BRAIN BEHAVIOR AND IMMUNITY

Changes of Colonic Bacterial Composition in Parkinson’s Disease and Other Neurodegenerative Diseases

(2018) Sara Gerhardt et al.   Nutrients

Ginger and 6-shogaol protect intestinal tight junction and enteric dopaminergic neurons against 1-methyl-4-phenyl 1,2,3,6-tetrahydropyridine in mice

(2018) Eugene Huh et al.   NUTRITIONAL NEUROSCIENCE

TLR4 absence reduces neuroinflammation and inflammasome activation in Parkinson’s diseases in vivo model

(2018) Michela Campolo et al.   BRAIN BEHAVIOR AND IMMUNITY

Unraveling gut microbiota in Parkinson's disease and atypical parkinsonism

(2018) Michela Barichella et al.   MOVEMENT DISORDERS

Lactoferrin ameliorates dopaminergic neurodegeneration and motor deficits in MPTP-treated mice

(2018) Shuang-Feng Xu et al.   Redox Biology

Microbial profiles of a drinking water resource based on different 16S rRNA V regions during a heavy cyanobacterial bloom in Lake Taihu, China

(2017) Junyi Zhang et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Chicoric acid supplementation prevents systemic inflammation-induced memory impairment and amyloidogenesis via inhibition of NF-κB

(2017) Qian Liu et al.   FASEB JOURNAL

Chicoric acid suppresses BAFF expression in B lymphocytes by inhibiting NF-κB activity

(2017) Lingxi Chen et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The role of trophic factors and inflammatory processes in physical activity-induced neuroprotection in Parkinson’s disease

(2017) Ewelina Pałasz et al.   Postepy Higieny I Medycyny Doswiadczalnej

Chicoric acid is a potent anti-atherosclerotic ingredient by anti-oxidant action and anti-inflammation capacity

(2017) Kun-Ling Tsai et al.   Oncotarget

Chicoric acid supplementation ameliorates cognitive impairment induced by oxidative stress via promotion of antioxidant defense system

(2017) Yutang Wang et al.   RSC Advances

Dietary phenolic acids reverse insulin resistance, hyperglycaemia, dyslipidaemia, inflammation and oxidative stress in high-fructose diet-induced metabolic syndrome rats

(2017) Oluwayemisi B. Ibitoye et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

Gut microbiome alterations in Alzheimer’s disease

(2017) Nicholas M. Vogt et al.   Scientific Reports

Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson’s Disease

(2016) Timothy R. Sampson et al.   CELL

Activation of Bacteroides fragilis toxin by a novel bacterial protease contributes to anaerobic sepsis in mice

(2016) Vivian M Choi et al.   NATURE MEDICINE

Crosstalk between Microbiota-Derived Short-Chain Fatty Acids and Intestinal Epithelial HIF Augments Tissue Barrier Function

(2015) Caleb J. Kelly et al.   Cell Host & Microbe

Cichoric Acid Reverses Insulin Resistance and Suppresses Inflammatory Responses in the Glucosamine-Induced HepG2 Cells

(2015) Di Zhu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Evaluation of Hepatocyteprotective and Anti-hepatitis B Virus Properties of Cichoric Acid from Cichorium intybus Leaves in Cell Culture

(2014) Hong-Li Zhang et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

The composition of the gut microbiota shapes the colon mucus barrier

(2014) H. E. Jakobsson et al.   EMBO REPORTS

Regulatory B cells are induced by gut microbiota–driven interleukin-1β and interleukin-6 production

(2014) Elizabeth C Rosser et al.   NATURE MEDICINE

The gut microbiota influences blood-brain barrier permeability in mice

(2014) V. Braniste et al.   Science Translational Medicine

Chicoric acid prevents obesity by attenuating hepatic steatosis, inflammation and oxidative stress in high-fat diet-fed mice

(2013) Haifang Xiao et al.   FOOD RESEARCH INTERNATIONAL

Polyphenols Protect the Epithelial Barrier Function of Caco-2 Cells Exposed to Indomethacin through the Modulation of Occludin and Zonula Occludens-1 Expression

(2013) Catalina Carrasco-Pozo et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Benefits of polyphenols on gut microbiota and implications in human health

(2013) Fernando Cardona et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Parkinson's Disease and Parkinsonism: Neuropathology

(2013) D. W. Dickson   Cold Spring Harbor Perspectives in Medicine

Gut Microbial Products Regulate Murine Gastrointestinal Motility via Toll-Like Receptor 4 Signaling

(2012) Mallappa Anitha et al.   GASTROENTEROLOGY

Colonic inflammation in Parkinson's disease

(2012) David Devos et al.   NEUROBIOLOGY OF DISEASE

Regulation of Inflammation by Short Chain Fatty Acids

(2011) Marco A.R. Vinolo et al.   Nutrients

Brain?Gut?Microbe Communication in Health and Disease

(2011) Sue Grenham et al.   Frontiers in Physiology

Pyrosequencing study of fecal microflora of autistic and control children

(2010) Sydney M. Finegold et al.   ANAEROBE

Toll-like Receptors 3, 4, and 7 Are Expressed in the Enteric Nervous System and Dorsal Root Ganglia

(2009) Isabella Barajon et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Behavior, neurotransmitters and inflammation in three regimens of the MPTP mouse model of Parkinson's disease

(2009) Dirk W. Luchtman et al.   PHYSIOLOGY & BEHAVIOR

Interleukin-1β impairs brain derived neurotrophic factor-induced signal transduction

(2007) Liqi Tong et al.   NEUROBIOLOGY OF AGING