A possible potential COVID-19 drug candidate: Diethyl 2-(2-(2-(3-methyl-2-oxoquinoxalin-1(2H)-yl)acetyl)hydrazono)malonate: Docking of disordered independent molecules of a novel crystal structure, HSA/DFT/XRD and cytotoxicity

Anakinra for patients with COVID-19: a meta-analysis of non-randomized cohort studies.

(2021) Laura Pasin et al.   European Journal of Internal Medicine

Design, synthesis, structural and molecular characterization, toxicity, psychotropic activity and molecular docking evaluation of a novel phenytoin derivative: 3-decyl-5,5-diphenylimidazolidine-2,4-dione

(2021) Walid Guerrab et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Synthesis, crystal structure, DFT calculations, Hirshfeld surface analysis, energy frameworks, molecular dynamics and docking studies of novel isoxazolequinoxaline derivative (IZQ) as anti-cancer drug

(2021) Nadeem Abad et al.   JOURNAL OF MOLECULAR STRUCTURE

Novel antioxidant quinoxaline derivative: Synthesis, crystal structure, theoretical studies, antidiabetic activity and molecular docking study

(2021) Mohcine Missioui et al.   JOURNAL OF MOLECULAR STRUCTURE

Synthesis, structural characterisation and theoretical studies of a novel pyridazine derivative: Investigations of anti-inflammatory activity and inhibition of α-glucosidase

(2021) Younes Zaoui et al.   JOURNAL OF MOLECULAR STRUCTURE

Docking of disordered independent molecules of novel crystal structure of (N-(4-methoxyphenyl)-2-(3-methyl-2-oxo-3,4-dihydroquinoxalin-1(2H)-yl)acetamide as anti-COVID-19 and anti-Alzheimer's disease. Crystal structure, HSA/DFT/XRD

(2021) Mohcine Missioui et al.   JOURNAL OF MOLECULAR STRUCTURE

[Cu(dipicolinoylamide)(NO3)(H2O)] as anti-COVID-19 and antibacterial drug candidate: Design, synthesis, crystal structure, DFT and molecular docking

(2021) Laila H. Abdel-Rahman et al.   JOURNAL OF MOLECULAR STRUCTURE

Connecting With Patients—The Missing Links

(2020) Lisa Sanders et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Clinical evidence does not support corticosteroid treatment for 2019-nCoV lung injury

(2020) Clark D Russell et al.   LANCET

Efficacy and safety of tocilizumab in severe COVID-19 patients: a single-centre retrospective cohort study

(2020) Corrado Campochiaro et al.   European Journal of Internal Medicine

Profiling COVID-19 pneumonia progressing into the cytokine storm syndrome: results from a single Italian Centre study on tocilizumab versus standard of care

(2020) Luca Quartuccio et al.   JOURNAL OF CLINICAL VIROLOGY

Baricitinib therapy in COVID-19: A pilot study on safety and clinical impact

(2020) Fabrizio Cantini et al.   JOURNAL OF INFECTION

Tocilizumab treatment in COVID-19: A single center experience

(2020) Pan Luo et al.   JOURNAL OF MEDICAL VIROLOGY

Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors

(2020) Zhenming Jin et al.   NATURE

A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19

(2020) Bin Cao et al.   NEW ENGLAND JOURNAL OF MEDICINE

Tocilizumab for Treatment of Severe COVID-19 Patients: Preliminary Results from SMAtteo COvid19 REgistry (SMACORE)

(2020) Marta Colaneri et al.   Microorganisms

Discovery of 1,2,3-triazole based quinoxaline-1,4-di-N-oxide derivatives as potential anti-tubercular agents

(2020) Singireddi Srinivasarao et al.   BIOORGANIC CHEMISTRY

In silico studies on therapeutic agents for COVID-19: Drug repurposing approach

(2020) Bhumi Shah et al.   LIFE SCIENCES

Synthesis and crystal structure of 1-octyl-3-phenylquinoxalin-2(1H)-one, C22H26N2O

(2020) Nadeem Abad et al.   ZEITSCHRIFT FUR KRISTALLOGRAPHIE-NEW CRYSTAL STRUCTURES

Synthesis and crystal structure of 2-azido-N-phenylacetamide, C8H8N4O

(2020) Walid Guerrab et al.   ZEITSCHRIFT FUR KRISTALLOGRAPHIE-NEW CRYSTAL STRUCTURES

Safety and efficacy of hydroxychloroquine in 152 outpatients with confirmed COVID-19: A pilot observational study

(2020) Ozgur Sogut et al.   AMERICAN JOURNAL OF EMERGENCY MEDICINE

Quinoxaline-PABA bipartite hybrid derivatization approach: Design and search for antimicrobial agents

(2019) Harun M. Patel et al.   JOURNAL OF MOLECULAR STRUCTURE

Discovery and evaluation of novel synthetic 5-alkyl-4-oxo-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoxaline-1-carbox-amide derivatives as anti-inflammatory agents

(2019) Qing-Kun Shen et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Response of preantral follicles exposed to quinoxaline: A new compound with anticancer potential

(2019) Denise Damasceno Guerreiro et al.   RESEARCH IN VETERINARY SCIENCE

Synthesis of a novel phenytoin derivative: Crystal structure, Hirshfeld surface analysis and DFT calculations

(2019) Walid Guerrab et al.   JOURNAL OF MOLECULAR STRUCTURE

Synthesis, spectroscopic (FT-IR, UV–Vis), experimental (X-Ray) and theoretical (HF/DFT) study of: ( E )-2-Chloro-N-((4-nitrocyclopenta-1,3-dienyl)methylene)benzenamine

(2018) Gonca Özdemir Tarı et al.   JOURNAL OF MOLECULAR STRUCTURE

CLC-Pred: A freely available web-service for in silico prediction of human cell line cytotoxicity for drug-like compounds

(2018) Alexey A. Lagunin et al.   PLoS One

Synthesis and Molecular Docking Study of Novel Hybrids of 1,3,4‐Oxadiazoles and Quinoxaline as a Potential Analgesic and Anti‐Inflammatory Agents

(2018) Dhansay Dewangan et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

A structural study of fentanyl by DFT calculations, NMR and IR spectroscopy

(2017) Zahra Asadi et al.   JOURNAL OF MOLECULAR STRUCTURE

Vibrational spectra, electronic properties and effect of alkyl chain length on chemical stability of nematogens – A comparision using DFT and HF methods

(2017) Seema Prasad et al.   MOLECULAR CRYSTALS AND LIQUID CRYSTALS

Computational platform Way2Drug: from the prediction of biological activity to drug repurposing

(2017) D. S. Druzhilovskiy et al.   RUSSIAN CHEMICAL BULLETIN

Design, synthesis and anti-HIV activity of novel quinoxaline derivatives

(2016) Saloni B. Patel et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Experimental and theoretical studies for mild steel corrosion inhibition in 1.0M HCl by three new quinoxalinone derivatives

(2016) A. Tazouti et al.   JOURNAL OF MOLECULAR LIQUIDS

SHELXT– Integrated space-group and crystal-structure determination

(2015) George M. Sheldrick   Acta Crystallographica A-Foundation and Advances

Comparison of silver and molybdenum microfocus X-ray sources for single-crystal structure determination

(2015) Lennard Krause et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Synthesis and anti-TMV activity of novel β-amino acid ester derivatives containing quinazoline and benzothiazole moieties

(2014) Han Xiao et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Pharmacological Profile of Quinoxalinone

(2014) Youssef Ramli et al.   Journal of Chemistry

Synthesis and cytotoxicity of diam(m)ineplatinum(II) complexes with 2,2-bis(hydroxymethyl)malonate as the leaving group

(2012) Yingjuan Xing et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

FT-Raman, FT-IR, UV spectra and DFT and ab initio calculations on monomeric and dimeric structures of 3,5-pyridinedicarboxylic acid

(2012) A. Nataraj et al.   JOURNAL OF MOLECULAR STRUCTURE

Ethyl malonate amides: A diketo acid offspring fragment for HIV integrase inhibition

(2011) Katarzyna Serafin et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Transition metal complexes of thiosemicarbazones with quinoxaline hub: an emphasis on antidiabetic property

(2011) Naveen V. Kulkarni et al.   MEDICINAL CHEMISTRY RESEARCH

Individual and common inhibitors of coronavirus and picornavirus main proteases

(2009) Chih-Jung Kuo et al.   FEBS LETTERS