The impact of physiological metabolite levels on serine uptake, synthesis and utilization in cancer cells
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Title
The impact of physiological metabolite levels on serine uptake, synthesis and utilization in cancer cells
Authors
Keywords
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Journal
Nature Communications
Volume 12, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2021-10-26
DOI
10.1038/s41467-021-26395-5
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Note: Only part of the references are listed.- Serine synthesis pathway inhibition cooperates with dietary serine and glycine limitation for cancer therapy
- (2021) Mylène Tajan et al. Nature Communications
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- (2019) Johan Vande Voorde et al. Science Advances
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- (2019) Arianne E. Rodriguez et al. Cell Metabolism
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- (2019) Mark R Sullivan et al. eLife
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- (2019) Teresa W. M. Fan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Potential Mechanisms Connecting Purine Metabolism and Cancer Therapy
- (2018) Jie Yin et al. Frontiers in Immunology
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- (2016) Dan Y. Gui et al. Cell Metabolism
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- (2016) Ayman W. El-Hattab MOLECULAR GENETICS AND METABOLISM
- High Expression of PHGDH Predicts Poor Prognosis in Non–Small Cell Lung Cancer
- (2016) Jinhong Zhu et al. Translational Oncology
- Increased Expression of PHGDH and Prognostic Significance in Colorectal Cancer
- (2016) Xiao-qin Jia et al. Translational Oncology
- Serine one-carbon catabolism with formate overflow
- (2016) J. Meiser et al. Science Advances
- D-Serine Is a Substrate for Neutral Amino Acid Transporters ASCT1/SLC1A4 and ASCT2/SLC1A5, and Is Transported by Both Subtypes in Rat Hippocampal Astrocyte Cultures
- (2016) Alan C. Foster et al. PLoS One
- NRF2 regulates serine biosynthesis in non–small cell lung cancer
- (2015) Gina M DeNicola et al. NATURE GENETICS
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- (2015) Andrew N. Lane et al. NUCLEIC ACIDS RESEARCH
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- (2015) Cedric Bardy et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Serine Deprivation Enhances Antineoplastic Activity of Biguanides
- (2014) S.-P. Gravel et al. CANCER RESEARCH
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- (2014) Kıvanç Birsoy et al. NATURE
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- (2014) Christiaan F. Labuschagne et al. Cell Reports
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- (2012) Ralph W. Adams et al. CHEMICAL COMMUNICATIONS
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- Functional genomics reveal that the serine synthesis pathway is essential in breast cancer
- (2011) Richard Possemato et al. NATURE
- The GCN2-ATF4 pathway is critical for tumour cell survival and proliferation in response to nutrient deprivation
- (2010) Jiangbin Ye et al. EMBO JOURNAL
- Metabolic profiling in colorectal cancer reveals signature metabolic shifts during tumorigenesis
- (2010) E. S. Ong et al. MOLECULAR & CELLULAR PROTEOMICS
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