A pandemic-enabled comparison of discovery platforms demonstrates a naïve antibody library can match the best immune-sourced antibodies
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Title
A pandemic-enabled comparison of discovery platforms demonstrates a naïve antibody library can match the best immune-sourced antibodies
Authors
Keywords
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Journal
Nature Communications
Volume 13, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2022-01-24
DOI
10.1038/s41467-021-27799-z
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Note: Only part of the references are listed.- Broad and potent activity against SARS-like viruses by an engineered human monoclonal antibody
- (2021) C. Garrett Rappazzo et al. SCIENCE
- Neutralizing Human Antibodies against Severe Acute Respiratory Syndrome Coronavirus 2 Isolated from a Human Synthetic Fab Phage Display Library
- (2021) Yu Jung Kim et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Neutralizing antibodies targeting the SARS‐CoV ‐2 receptor binding domain isolated from a naïve human antibody library
- (2021) Benjamin N. Bell et al. PROTEIN SCIENCE
- SARS-CoV-2 neutralizing human recombinant antibodies selected from pre-pandemic healthy donors binding at RBD-ACE2 interface
- (2021) Federico Bertoglio et al. Nature Communications
- Multi-clonal SARS-CoV-2 neutralization by antibodies isolated from severe COVID-19 convalescent donors
- (2021) Michael Mor et al. PLoS Pathogens
- Neutralizing and protective human monoclonal antibodies recognizing the N-terminal domain of the SARS-CoV-2 spike protein
- (2021) Naveenchandra Suryadevara et al. CELL
- Engineered Ultra-High Affinity Synthetic Antibodies for SARS-CoV-2 Neutralization and Detection
- (2021) Tomasz Slezak et al. JOURNAL OF MOLECULAR BIOLOGY
- SARS-CoV-2 RBD antibodies that maximize breadth and resistance to escape
- (2021) Tyler N. Starr et al. NATURE
- Defining variant-resistant epitopes targeted by SARS-CoV-2 antibodies: A global consortium study
- (2021) Kathryn M. Hastie et al. SCIENCE
- Cross-Reactive SARS-CoV-2 Neutralizing Antibodies From Deep Mining of Early Patient Responses
- (2021) Georgia Bullen et al. Frontiers in Immunology
- Screening of potent neutralizing antibodies against SARS-CoV-2 using convalescent patients-derived phage-display libraries
- (2021) Yongbing Pan et al. Cell Discovery
- Antibody Cocktail Exhibits Broad Neutralization Activity Against SARS-CoV-2 and SARS-CoV-2 Variants
- (2021) Yuanyuan Qu et al. VIROLOGICA SINICA
- Assessing the binding properties of the anti-PD-1 antibody landscape using label-free biosensors
- (2020) Michael E. Brown et al. PLoS One
- Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation
- (2020) Daniel Wrapp et al. SCIENCE
- Potent binding of 2019 novel coronavirus spike protein by a SARS coronavirus-specific human monoclonal antibody
- (2020) Xiaolong Tian et al. Emerging Microbes & Infections
- Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies
- (2020) Daniel Wrapp et al. CELL
- SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
- (2020) Markus Hoffmann et al. CELL
- Human monoclonal antibodies block the binding of SARS-CoV-2 spike protein to angiotensin converting enzyme 2 receptor
- (2020) Xiangyu Chen et al. Cellular & Molecular Immunology
- A human neutralizing antibody targets the receptor binding site of SARS-CoV-2
- (2020) Rui Shi et al. NATURE
- Human neutralizing antibodies elicited by SARS-CoV-2 infection
- (2020) Bin Ju et al. NATURE
- Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody
- (2020) Dora Pinto et al. NATURE
- A noncompeting pair of human neutralizing antibodies block COVID-19 virus binding to its receptor ACE2
- (2020) Yan Wu et al. SCIENCE
- A highly conserved cryptic epitope in the receptor binding domains of SARS-CoV-2 and SARS-CoV
- (2020) Meng Yuan et al. SCIENCE
- DNA vaccine protection against SARS-CoV-2 in rhesus macaques
- (2020) Jingyou Yu et al. SCIENCE
- Potent Neutralizing Antibodies against SARS-CoV-2 Identified by High-Throughput Single-Cell Sequencing of Convalescent Patients’ B Cells
- (2020) Yunlong Cao et al. CELL
- Analysis of a SARS-CoV-2-Infected Individual Reveals Development of Potent Neutralizing Antibodies with Limited Somatic Mutation
- (2020) Emilie Seydoux et al. IMMUNITY
- Identification of an anti-SARS-CoV-2 receptor binding domain directed human monoclonal antibody from a naïve semi-synthetic library
- (2020) Hilal Ahmed Parray et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Potently Neutralizing Antibody Protects Mice against SARS-CoV-2 Infection
- (2020) Wafaa B. Alsoussi et al. JOURNAL OF IMMUNOLOGY
- Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial
- (2020) Pedro M Folegatti et al. LANCET
- Convergent antibody responses to SARS-CoV-2 in convalescent individuals
- (2020) Davide F. Robbiani et al. NATURE
- Potent neutralizing antibodies against multiple epitopes on SARS-CoV-2 spike
- (2020) Lihong Liu et al. NATURE
- Potently neutralizing and protective human antibodies against SARS-CoV-2
- (2020) Seth J. Zost et al. NATURE
- Rapid isolation and profiling of a diverse panel of human monoclonal antibodies targeting the SARS-CoV-2 spike protein
- (2020) Seth J. Zost et al. NATURE MEDICINE
- A neutralizing human antibody binds to the N-terminal domain of the Spike protein of SARS-CoV-2
- (2020) Xiangyang Chi et al. SCIENCE
- Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model
- (2020) Thomas F. Rogers et al. SCIENCE
- Studies in humanized mice and convalescent humans yield a SARS-CoV-2 antibody cocktail
- (2020) Johanna Hansen et al. SCIENCE
- Broad neutralization of SARS-related viruses by human monoclonal antibodies
- (2020) Anna Z. Wec et al. SCIENCE
- COVID‐19 drug repurposing: Summary statistics on current clinical trials and promising untested candidates
- (2020) J. Wes Ulm et al. Transboundary and Emerging Diseases
- Human-IgG-Neutralizing Monoclonal Antibodies Block the SARS-CoV-2 Infection
- (2020) Jinkai Wan et al. Cell Reports
- CoV-AbDab: the Coronavirus Antibody Database
- (2020) Matthew I J Raybould et al. BIOINFORMATICS
- A Therapeutic Non-self-reactive SARS-CoV-2 Antibody Protects from Lung Pathology in a COVID-19 Hamster Model
- (2020) Jakob Kreye et al. CELL
- SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies
- (2020) Christopher O. Barnes et al. NATURE
- Ultrapotent human antibodies protect against SARS-CoV-2 challenge via multiple mechanisms
- (2020) M. Alejandra Tortorici et al. SCIENCE
- A panel of human neutralizing mAbs targeting SARS-CoV-2 spike at multiple epitopes
- (2020) Tal Noy-Porat et al. Nature Communications
- Enhanced SARS-CoV-2 neutralization by dimeric IgA
- (2020) Zijun Wang et al. Science Translational Medicine
- A Potent SARS-CoV-2 Neutralizing Human Monoclonal Antibody That Reduces Viral Burden and Disease Severity in Syrian Hamsters
- (2020) Anna C. Fagre et al. Frontiers in Immunology
- A high-throughput platform for population reformatting and mammalian expression of phage display libraries to enable functional screening as full-length IgG
- (2017) Xiaodong Xiao et al. mAbs
- Biophysical properties of the clinical-stage antibody landscape
- (2017) Tushar Jain et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Recombinant renewable polyclonal antibodies
- (2014) Fortunato Ferrara et al. mAbs
- A fully synthetic human Fab antibody library based on fixed VH/VL framework pairings with favorable biophysical properties
- (2013) Thomas Tiller et al. mAbs
- High-throughput screening for developability during early-stage antibody discovery using self-interaction nanoparticle spectroscopy
- (2013) Yuqi Liu et al. mAbs
- Using Phage and Yeast Display to Select Hundreds of Monoclonal Antibodies: Application to Antigen 85, a Tuberculosis Biomarker
- (2012) Fortunato Ferrara et al. PLoS One
- HuCAL PLATINUM, a Synthetic Fab Library Optimized for Sequence Diversity and Superior Performance in Mammalian Expression Systems
- (2011) Josef Prassler et al. JOURNAL OF MOLECULAR BIOLOGY
- High‐Throughput Assessment of Thermal and Colloidal Stability Parameters for Monoclonal Antibody Formulations
- (2011) Feng He et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Polyreactivity increases the apparent affinity of anti-HIV antibodies by heteroligation
- (2010) Hugo Mouquet et al. NATURE
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