Machine learning-guided acyl-ACP reductase engineering for improved in vivo fatty alcohol production

Production of 1-octanol in Escherichia coli by a high flux thioesterase route

(2020) Néstor J. Hernández Lozada et al.   METABOLIC ENGINEERING

Lessons from Two Design–Build–Test–Learn Cycles of Dodecanol Production in Escherichia coli Aided by Machine Learning

(2019) Paul Opgenorth et al.   ACS Synthetic Biology

Machine-learning-guided directed evolution for protein engineering

(2019) Kevin K. Yang et al.   NATURE METHODS

Machine learning-guided channelrhodopsin engineering enables minimally invasive optogenetics

(2019) Claire N. Bedbrook et al.   NATURE METHODS

Unified rational protein engineering with sequence-based deep representation learning

(2019) Ethan C. Alley et al.   NATURE METHODS

Efficient flexible backbone protein–protein docking for challenging targets

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Anaerobic production of medium-chain fatty alcohols via a β-reduction pathway

(2018) Christopher R. Mehrer et al.   METABOLIC ENGINEERING

Matching Protein Interfaces for Improved Medium-Chain Fatty Acid Production

(2018) Stephen Sarria et al.   ACS Synthetic Biology

Highly Active C8-Acyl-ACP Thioesterase Variant Isolated by a Synthetic Selection Strategy

(2018) Néstor J. Hernández Lozada et al.   ACS Synthetic Biology

Machine-Learning-Guided Mutagenesis for Directed Evolution of Fluorescent Proteins

(2018) Yutaka Saito et al.   ACS Synthetic Biology

Machine learning to design integral membrane channelrhodopsins for efficient eukaryotic expression and plasma membrane localization

(2017) Claire N. Bedbrook et al.   PLoS Computational Biology

Metabolic engineering strategies for microbial synthesis of oleochemicals

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Versatility of Acyl-Acyl Carrier Protein Synthetases

(2014) Joris Beld et al.   CHEMISTRY & BIOLOGY

The role of distant mutations and allosteric regulation on LovD active site dynamics

(2014) Gonzalo Jiménez-Osés et al.   Nature Chemical Biology

Fatty alcohol production in engineered E. coli expressing Marinobacter fatty acyl-CoA reductases

(2013) Aiqiu Liu et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Production of medium chain length fatty alcohols from glucose in Escherichia coli

(2013) J. Tyler Youngquist et al.   METABOLIC ENGINEERING

Metabolic engineering of fatty acyl-ACP reductase-dependent pathway to improve fatty alcohol production in Escherichia coli

(2013) Ran Liu et al.   METABOLIC ENGINEERING

Navigating the protein fitness landscape with Gaussian processes

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Information-Theoretic Regret Bounds for Gaussian Process Optimization in the Bandit Setting

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Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Characterization of a Fatty Acyl-CoA Reductase fromMarinobacter aquaeoleiVT8: A Bacterial Enzyme Catalyzing the Reduction of Fatty Acyl-CoA to Fatty Alcohol

(2011) Robert M. Willis et al.   BIOCHEMISTRY

A prokaryotic acyl-CoA reductase performing reduction of fatty acyl-CoA to fatty alcohol

(2011) Per Hofvander et al.   FEBS LETTERS

A process for microbial hydrocarbon synthesis: Overproduction of fatty acids inEscherichia coliand catalytic conversion to alkanes

(2010) Rebecca M. Lennen et al.   BIOTECHNOLOGY AND BIOENGINEERING

Microbial production of fatty-acid-derived fuels and chemicals from plant biomass

(2010) Eric J. Steen et al.   NATURE

Microbial Biosynthesis of Alkanes

(2010) A. Schirmer et al.   SCIENCE