Immune cell topography predicts response to PD-1 blockade in cutaneous T cell lymphoma
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Immune cell topography predicts response to PD-1 blockade in cutaneous T cell lymphoma
Authors
Keywords
-
Journal
Nature Communications
Volume 12, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2021-11-18
DOI
10.1038/s41467-021-26974-6
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- CXCL13 shapes immunoactive tumor microenvironment and enhances the efficacy of PD-1 checkpoint blockade in high-grade serous ovarian cancer
- (2021) Moran Yang et al. Journal for ImmunoTherapy of Cancer
- Highly multiplexed tissue imaging using repeated oligonucleotide exchange reaction
- (2021) Julia Kennedy‐Darling et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Highly Multiplexed Phenotyping of Immunoregulatory Proteins in the Tumor Microenvironment by CODEX Tissue Imaging
- (2021) Darci Phillips et al. Frontiers in Immunology
- CODEX multiplexed tissue imaging with DNA-conjugated antibodies
- (2021) Sarah Black et al. Nature Protocols
- The single-cell pathology landscape of breast cancer
- (2020) Hartland W. Jackson et al. NATURE
- Intratumoral CD4+ T Cells Mediate Anti-tumor Cytotoxicity in Human Bladder Cancer
- (2020) David Y. Oh et al. CELL
- Coordinated Cellular Neighborhoods Orchestrate Antitumoral Immunity at the Colorectal Cancer Invasive Front
- (2020) Christian M. Schürch et al. CELL
- ARID1A mutation plus CXCL13 expression act as combinatorial biomarkers to predict responses to immune checkpoint therapy in mUCC
- (2020) Sangeeta Goswami et al. Science Translational Medicine
- Spatial Signatures Identify Immune Escape via PD-1 as a Defining Feature of T-cell/Histiocyte-rich Large B-cell Lymphoma
- (2020) Gabriel K. Griffin et al. BLOOD
- The 2018 update of the WHO-EORTC classification for primary cutaneous lymphomas
- (2019) Rein Willemze et al. BLOOD
- Single-cell profiling of cutaneous T-cell lymphoma reveals underlying heterogeneity associated with disease progression
- (2019) Nicholas Borcherding et al. CLINICAL CANCER RESEARCH
- Single-Cell Lymphocyte Heterogeneity in Advanced Cutaneous T-cell Lymphoma Skin Tumors
- (2019) Alyxzandria M. Gaydosik et al. CLINICAL CANCER RESEARCH
- Mobilization of CD8+ T Cells via CXCR4 Blockade Facilitates PD-1 Checkpoint Therapy in Human Pancreatic Cancer
- (2019) Yongwoo David Seo et al. CLINICAL CANCER RESEARCH
- Determining cell type abundance and expression from bulk tissues with digital cytometry
- (2019) Aaron M. Newman et al. NATURE BIOTECHNOLOGY
- Comprehensive Integration of Single-Cell Data
- (2019) Tim Stuart et al. CELL
- Protective and pathogenic roles of resident memory T cells in human skin disorders
- (2019) Rei Watanabe JOURNAL OF DERMATOLOGICAL SCIENCE
- Moving beyond P values: data analysis with estimation graphics
- (2019) Joses Ho et al. NATURE METHODS
- CXCL13 and Its Receptor CXCR5 in Cancer: Inflammation, Immune Response, and Beyond
- (2019) Marcelo G. Kazanietz et al. Frontiers in Endocrinology
- Comparison of Biomarker Modalities for Predicting Response to PD-1/PD-L1 Checkpoint Blockade
- (2019) Steve Lu et al. JAMA Oncology
- Gene-expression profiling of single cells from archival tissue with laser-capture microdissection and Smart-3SEQ
- (2019) Joseph W Foley et al. GENOME RESEARCH
- Pembrolizumab in Relapsed and Refractory Mycosis Fungoides and Sézary Syndrome: A Multicenter Phase II Study
- (2019) Michael S. Khodadoust et al. JOURNAL OF CLINICAL ONCOLOGY
- A transcriptionally and functionally distinct PD-1+ CD8+ T cell pool with predictive potential in non-small-cell lung cancer treated with PD-1 blockade
- (2018) Daniela S. Thommen et al. NATURE MEDICINE
- Understanding the tumor immune microenvironment (TIME) for effective therapy
- (2018) Mikhail Binnewies et al. NATURE MEDICINE
- Cancer immunotherapy using checkpoint blockade
- (2018) Antoni Ribas et al. SCIENCE
- High-throughput sequencing of the T cell receptor β gene identifies aggressive early-stage mycosis fungoides
- (2018) Adele de Masson et al. Science Translational Medicine
- Primary T cells from cutaneous T-cell lymphoma skin explants display an exhausted immune checkpoint profile
- (2018) Christiane Querfeld et al. Cancer Immunology Research
- Development of PD-1 and PD-L1 inhibitors as a form of cancer immunotherapy: a comprehensive review of registration trials and future considerations
- (2018) Jun Gong et al. Journal for ImmunoTherapy of Cancer
- OUP accepted manuscript
- (2018) AMERICAN JOURNAL OF CLINICAL PATHOLOGY
- Deep Profiling of Mouse Splenic Architecture with CODEX Multiplexed Imaging
- (2018) Yury Goltsev et al. CELL
- A Structured Tumor-Immune Microenvironment in Triple Negative Breast Cancer Revealed by Multiplexed Ion Beam Imaging
- (2018) Leeat Keren et al. CELL
- TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells
- (2018) Sanjeev Mariathasan et al. NATURE
- Chemokine Network and Overall Survival in TP53 Wild-Type and Mutant Ovarian Cancer
- (2018) Rosa Mistica C. Ignacio et al. Immune Network
- Multidimensional, quantitative assessment of PD-1/PD-L1 expression in patients with Merkel cell carcinoma and association with response to pembrolizumab
- (2018) Nicolas A. Giraldo et al. Journal for ImmunoTherapy of Cancer
- IFN-γ–related mRNA profile predicts clinical response to PD-1 blockade
- (2017) Mark Ayers et al. JOURNAL OF CLINICAL INVESTIGATION
- TIGIT and Helios Are Highly Expressed on CD4 + T Cells in Sézary Syndrome Patients
- (2017) Neha Jariwala et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- lmerTest Package: Tests in Linear Mixed Effects Models
- (2017) Alexandra Kuznetsova et al. Journal of Statistical Software
- Spatial computation of intratumoral T cells correlates with survival of patients with pancreatic cancer
- (2017) Julienne L. Carstens et al. Nature Communications
- Ex Vivo Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids
- (2017) Russell W. Jenkins et al. Cancer Discovery
- Immunotherapy and tumor microenvironment
- (2016) Haidong Tang et al. CANCER LETTERS
- PD-L1 expression in cancer patients receiving anti PD-1/PD-L1 antibodies: A systematic review and meta-analysis
- (2016) Sara Gandini et al. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
- Nivolumab in Patients With Relapsed or Refractory Hematologic Malignancy: Preliminary Results of a Phase Ib Study
- (2016) Alexander M. Lesokhin et al. JOURNAL OF CLINICAL ONCOLOGY
- NKG2C/E Marks the Unique Cytotoxic CD4 T Cell Subset, ThCTL, Generated by Influenza Infection
- (2016) Nikki B. Marshall et al. JOURNAL OF IMMUNOLOGY
- Automated mapping of phenotype space with single-cell data
- (2016) Nikolay Samusik et al. NATURE METHODS
- Mogamulizumab: 2 birds, 1 stone
- (2015) R. A. Wilcox BLOOD
- Cutaneous Lymphoma International Consortium Study of Outcome in Advanced Stages of Mycosis Fungoides and Sézary Syndrome: Effect of Specific Prognostic Markers on Survival and Development of a Prognostic Model
- (2015) Julia J. Scarisbrick et al. JOURNAL OF CLINICAL ONCOLOGY
- Immune Checkpoint Blockade in Cancer Therapy
- (2015) Michael A. Postow et al. JOURNAL OF CLINICAL ONCOLOGY
- Fitting Linear Mixed-Effects Models Usinglme4
- (2015) Douglas Bates et al. Journal of Statistical Software
- Genomic analysis of mycosis fungoides and Sézary syndrome identifies recurrent alterations in TNFR2
- (2015) Alexander Ungewickell et al. NATURE GENETICS
- PLCG1 mutations in cutaneous T-cell lymphomas
- (2014) José P. Vaqué et al. BLOOD
- Deficient Cutaneous Antibacterial Competence in Cutaneous T-Cell Lymphomas: Role of Th2-Mediated Biased Th17 Function
- (2014) K. Wolk et al. CLINICAL CANCER RESEARCH
- Prognostic B-cell Signatures Using mRNA-Seq in Patients with Subtype-Specific Breast and Ovarian Cancer
- (2014) M. D. Iglesia et al. CLINICAL CANCER RESEARCH
- The Future of Cancer Therapy: Selecting Patients Likely to Respond to PD1/L1 Blockade
- (2014) A. Ribas et al. CLINICAL CANCER RESEARCH
- Analysis and validation of tissue biomarkers for renal cell carcinoma using automated high-throughput evaluation of protein expression
- (2014) E. Jason Abel et al. HUMAN PATHOLOGY
- PD-1 blockade induces responses by inhibiting adaptive immune resistance
- (2014) Paul C. Tumeh et al. NATURE
- How Do CD4+ T Cells Detect and Eliminate Tumor Cells That Either Lack or Express MHC Class II Molecules?
- (2014) Ole Audun Werner Haabeth et al. Frontiers in Immunology
- Spatiotemporal Dynamics of Intratumoral Immune Cells Reveal the Immune Landscape in Human Cancer
- (2013) Gabriela Bindea et al. IMMUNITY
- IL-2 therapy promotes suppressive ICOS+ Treg expansion in melanoma patients
- (2013) Geok Choo Sim et al. JOURNAL OF CLINICAL INVESTIGATION
- The Role of IL-32 in Cutaneous T-Cell Lymphoma
- (2013) Hiraku Suga et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Enhancement of Tumor-Reactive Cytotoxic CD4+ T-cell Responses after Ipilimumab Treatment in Four Advanced Melanoma Patients
- (2013) S. Kitano et al. Cancer Immunology Research
- STAR: ultrafast universal RNA-seq aligner
- (2012) Alexander Dobin et al. BIOINFORMATICS
- Tumor Immunotherapy Directed at PD-1
- (2012) Antoni Ribas NEW ENGLAND JOURNAL OF MEDICINE
- Expression Patterns of the Immunosuppressive Proteins PD-1/CD279 and PD-L1/CD274 at Different Stages of Cutaneous T-Cell Lymphoma/Mycosis Fungoides
- (2011) Kanchan Kantekure et al. AMERICAN JOURNAL OF DERMATOPATHOLOGY
- Clinical End Points and Response Criteria in Mycosis Fungoides and Sézary Syndrome: A Consensus Statement of the International Society for Cutaneous Lymphomas, the United States Cutaneous Lymphoma Consortium, and the Cutaneous Lymphoma Task Force of the European Organisation for Research and Treatment of Cancer
- (2011) Elise A. Olsen et al. JOURNAL OF CLINICAL ONCOLOGY
- Sezary syndrome and mycosis fungoides arise from distinct T-cell subsets: a biologic rationale for their distinct clinical behaviors
- (2010) J. J. Campbell et al. BLOOD
- Genome-wide Loss-of-Function Screen Reveals an Important Role for the Proteasome in HDAC Inhibitor-Induced Apoptosis
- (2009) Susan Fotheringham et al. CANCER CELL
- Regulatory T Cells Recruited through CCL22/CCR4 Are Selectively Activated in Lymphoid Infiltrates Surrounding Primary Breast Tumors and Lead to an Adverse Clinical Outcome
- (2009) M. Gobert et al. CANCER RESEARCH
- Reduced Cytotoxic Function of Effector CD8+ T Cells Is Responsible for Indoleamine 2,3-Dioxygenase-Dependent Immune Suppression
- (2009) H. Liu et al. JOURNAL OF IMMUNOLOGY
- CXCL13 Is Highly Produced by Sezary Cells and Enhances Their Migratory Ability via a Synergistic Mechanism Involving CCL19 and CCL21 Chemokines
- (2008) M. C. Picchio et al. CANCER RESEARCH
- Fast unfolding of communities in large networks
- (2008) Vincent D Blondel et al. JOURNAL OF STATISTICAL MECHANICS-THEORY AND EXPERIMENT
- Expression of T-plastin, FoxP3 and other tumor-associated markers by leukemic T-cells of cutaneous T-cell lymphoma
- (2008) Elisabetta Capriotti et al. LEUKEMIA & LYMPHOMA
- A large genome center's improvements to the Illumina sequencing system
- (2008) Michael A Quail et al. NATURE METHODS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started