Plexin-B2 orchestrates collective stem cell dynamics via actomyosin contractility, cytoskeletal tension and adhesion

Evolution and diversity of semaphorins and plexins in choanoflagellates

(2021) Chrystian Junqueira Alves et al.   Genome Biology and Evolution

Mechanochemical control of epidermal stem cell divisions by B-plexins

(2021) Chen Jiang et al.   Nature Communications

Plexin-B2 facilitates glioblastoma infiltration by modulating cell biomechanics

(2021) Yong Huang et al.   Communications Biology

The guidance receptor plexin D1 is a mechanosensor in endothelial cells

(2020) Vedanta Mehta et al.   NATURE

LIM-Nebulette Reinforces Podocyte Structural Integrity by Linking Actin and Vimentin Filaments

(2020) Xuhua Ge et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Cellpose: a generalist algorithm for cellular segmentation

(2020) Carsen Stringer et al.   NATURE METHODS

Origin and evolution of plexins, semaphorins, and Met receptor tyrosine kinases

(2019) Chrystian Junqueira Alves et al.   Scientific Reports

The R package Rsubread is easier, faster, cheaper and better for alignment and quantification of RNA sequencing reads

(2019) Yang Liao et al.   NUCLEIC ACIDS RESEARCH

Mechanochemical Feedback Loops in Development and Disease

(2019) Edouard Hannezo et al.   CELL

Software for lattice light-sheet imaging of FRET biosensors, illustrated with a new Rap1 biosensor

(2019) Ellen C. O’Shaughnessy et al.   JOURNAL OF CELL BIOLOGY

Graph-based genome alignment and genotyping with HISAT2 and HISAT-genotype

(2019) Daehwan Kim et al.   NATURE BIOTECHNOLOGY

Sema4C/PlexinB2 signaling controls breast cancer cell growth, hormonal dependence and tumorigenic potential

(2018) Sreeharsha Gurrapu et al.   CELL DEATH AND DIFFERENTIATION

Identification of 22q13 genes most likely to contribute to Phelan McDermid syndrome

(2018) Andrew R. Mitz et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Tenascin-C derived signaling induces neuronal differentiation in a three-dimensional peptide nanofiber gel

(2018) Melike Sever et al.   Biomaterials Science

RAP2 mediates mechanoresponses of the Hippo pathway

(2018) Zhipeng Meng et al.   NATURE

From Ras to Rap and Back, a Journey of 35 Years

(2017) Johannes L. Bos   Cold Spring Harbor Perspectives in Medicine

Epidermis-Derived Semaphorin Promotes Dendrite Self-Avoidance by Regulating Dendrite-Substrate Adhesion in Drosophila Sensory Neurons

(2016) Shan Meltzer et al.   NEURON

Structural Basis for Plexin Activation and Regulation

(2016) Youxin Kong et al.   NEURON

Structure of the Plexin Ectodomain Bound by Semaphorin-Mimicking Antibodies

(2016) Kei Suzuki et al.   PLoS One

Transmembrane semaphorins: Multimodal signaling cues in development and cancer

(2016) Sreeharsha Gurrapu et al.   Cell Adhesion & Migration

Semaphorin-Plexin Signaling Controls Mitotic Spindle Orientation during Epithelial Morphogenesis and Repair

(2015) Jingjing Xia et al.   DEVELOPMENTAL CELL

Impaired cortical neurogenesis in plexin-B1 and -B2 double deletion mutant

(2015) Nicolas Daviaud et al.   Developmental Neurobiology

YAP is essential for tissue tension to ensure vertebrate 3D body shape

(2015) Sean Porazinski et al.   NATURE

NetworkAnalyst for statistical, visual and network-based meta-analysis of gene expression data

(2015) Jianguo Xia et al.   Nature Protocols

Structural mechanisms of plexin signaling

(2015) Heath G. Pascoe et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Plexin-B2 promotes invasive growth of malignant glioma

(2015) Audrey P. Le et al.   Oncotarget

Edges of human embryonic stem cell colonies display distinct mechanical properties and differentiation potential

(2015) Kathryn A. Rosowski et al.   Scientific Reports

Semaphorins and the dynamic regulation of synapse assembly, refinement, and function

(2014) Eleftheria Koropouli et al.   CURRENT OPINION IN NEUROBIOLOGY

Naiveté of the human pluripotent stem cell

(2014) Victoria L Mascetti et al.   NATURE BIOTECHNOLOGY

Hippo/YAP-mediated rigidity-dependent motor neuron differentiation of human pluripotent stem cells

(2014) Yubing Sun et al.   NATURE MATERIALS

Fluorogenic probes for live-cell imaging of the cytoskeleton

(2014) Gražvydas Lukinavičius et al.   NATURE METHODS

Improved vectors and genome-wide libraries for CRISPR screening

(2014) Neville E Sanjana et al.   NATURE METHODS

Generation of cerebral organoids from human pluripotent stem cells

(2014) Madeline A Lancaster et al.   Nature Protocols

Semaphorins and plexins as therapeutic targets

(2014) Thomas Worzfeld et al.   NATURE REVIEWS DRUG DISCOVERY

Cytosystems dynamics in self-organization of tissue architecture

(2013) Yoshiki Sasai   NATURE

Cerebral organoids model human brain development and microcephaly

(2013) Madeline A. Lancaster et al.   NATURE

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

Small-molecule inhibitors targeting G-protein-coupled Rho guanine nucleotide exchange factors

(2013) X. Shang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Soft microenvironments promote the early neurogenic differentiation but not self-renewal of human pluripotent stem cells

(2012) Albert J. Keung et al.   Integrative Biology

Plexin-B2 Regulates the Proliferation and Migration of Neuroblasts in the Postnatal and Adult Subventricular Zone

(2012) B. Saha et al.   JOURNAL OF NEUROSCIENCE

Transduction of mechanical and cytoskeletal cues by YAP and TAZ

(2012) Georg Halder et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Getting neural circuits into shape with semaphorins

(2012) R. Jeroen Pasterkamp   NATURE REVIEWS NEUROSCIENCE

Semaphorin signaling in angiogenesis, lymphangiogenesis and cancer

(2011) Atsuko Sakurai et al.   CELL RESEARCH

Role of YAP/TAZ in mechanotransduction

(2011) Sirio Dupont et al.   NATURE

Balancing forces: architectural control of mechanotransduction

(2011) Christopher C. DuFort et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

An ENU-Mutagenesis Screen in the Mouse: Identification of Novel Developmental Gene Functions

(2011) Carolien Wansleeben et al.   PLoS One

A Simple Hanging Drop Cell Culture Protocol for Generation of 3D Spheroids

(2011) Ramsey Foty   Jove-Journal of Visualized Experiments

Assembly of Fibronectin Extracellular Matrix

(2010) Purva Singh et al.   Annual Review of Cell and Developmental Biology

Mechanical control of tissue and organ development

(2010) T. Mammoto et al.   DEVELOPMENT

Integrated biochemical and mechanical signals regulate multifaceted human embryonic stem cell functions

(2010) Dong Li et al.   JOURNAL OF CELL BIOLOGY

Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics

(2010) Carsten Grashoff et al.   NATURE

Cell mechanics and the cytoskeleton

(2010) Daniel A. Fletcher et al.   NATURE

Cell adhesion: integrating cytoskeletal dynamics and cellular tension

(2010) J. Thomas Parsons et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Myosin II Dynamics Are Regulated by Tension in Intercalating Cells

(2009) Rodrigo Fernandez-Gonzalez et al.   DEVELOPMENTAL CELL

Plexin-B1 is a GTPase activating protein for M-Ras, remodelling dendrite morphology

(2009) Yasuhiro Saito et al.   EMBO REPORTS

Gene Deletion Mutants Reveal a Role for Semaphorin Receptors of the Plexin-B Family in Mechanisms Underlying Corticogenesis

(2009) A. Hirschberg et al.   MOLECULAR AND CELLULAR BIOLOGY

The Hippo–YAP pathway: new connections between regulation of organ size and cancer

(2008) Bin Zhao et al.   CURRENT OPINION IN CELL BIOLOGY

Morphogenetic movements driving neural tube closure in Xenopus require myosin IIB

(2008) Ana Rolo et al.   DEVELOPMENTAL BIOLOGY

Tyrosine phosphorylation in semaphorin signalling: shifting into overdrive

(2008) Mélanie Franco et al.   EMBO REPORTS

TEAD mediates YAP-dependent gene induction and growth control

(2008) B. Zhao et al.   GENES & DEVELOPMENT

Extracellular matrix dynamics in development and regenerative medicine

(2008) W. P. Daley et al.   JOURNAL OF CELL SCIENCE

Lifeact: a versatile marker to visualize F-actin

(2008) Julia Riedl et al.   NATURE METHODS

Semaphorin signaling: progress made and promises ahead

(2008) Yeping Zhou et al.   TRENDS IN BIOCHEMICAL SCIENCES