The histone methyltransferase DOT1L is a new epigenetic regulator of pulmonary fibrosis

More than a Genetic Code: Epigenetics of Lung Fibrosis

(2020) Krystian Bartczak et al.   Molecular Diagnosis & Therapy

New insights into TGF-β/Smad signaling in tissue fibrosis

(2018) He-He Hu et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Diagnostic criteria for idiopathic pulmonary fibrosis: a Fleischner Society White Paper

(2018) David A Lynch et al.   Lancet Respiratory Medicine

Hepatocyte Notch activation induces liver fibrosis in nonalcoholic steatohepatitis

(2018) Changyu Zhu et al.   Science Translational Medicine

The diagnosis of idiopathic pulmonary fibrosis: current and future approaches

(2017) Fernando J Martinez et al.   Lancet Respiratory Medicine

Efficacy of pirfenidone in patients with idiopathic pulmonary fibrosis with more preserved lung function

(2016) Carlo Albera et al.   EUROPEAN RESPIRATORY JOURNAL

Notch signaling modulates proliferative vitreoretinopathy via regulating retinal pigment epithelial-to-mesenchymal transition

(2016) Jingjing Zhang et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Incidence and prevalence of idiopathic interstitial pneumonia and idiopathic pulmonary fibrosis in Korea

(2016) H-E. Lee et al.   INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE

Targeting of the pulmonary capillary vascular niche promotes lung alveolar repair and ameliorates fibrosis

(2016) Zhongwei Cao et al.   NATURE MEDICINE

S-propargyl-cysteine attenuates inflammatory response in rheumatoid arthritis by modulating the Nrf2-ARE signaling pathway

(2016) Wei-Jun Wu et al.   Redox Biology

Mesenchymal Deficiency of Notch1 Attenuates Bleomycin-Induced Pulmonary Fibrosis

(2015) Biao Hu et al.   AMERICAN JOURNAL OF PATHOLOGY

The interplay of histone modifications - writers that read

(2015) T. Zhang et al.   EMBO REPORTS

Bleomycin in the setting of lung fibrosis induction: From biological mechanisms to counteractions

(2015) Veronica Della Latta et al.   PHARMACOLOGICAL RESEARCH

Microvascular Notch Signaling Is Upregulated in Response to Vascular Endothelial Growth Factor and Chronic Myocardial Ischemia

(2013) Antonio D. Lassaletta et al.   CIRCULATION JOURNAL

Bleomycin Induces Molecular Changes Directly Relevant to Idiopathic Pulmonary Fibrosis: A Model for “Active” Disease

(2013) Ruoqi Peng et al.   PLoS One

Pulmonary fibrosis: patterns and perpetrators

(2012) Paul W. Noble et al.   JOURNAL OF CLINICAL INVESTIGATION

Notch receptor–ligand binding and activation: Insights from molecular studies

(2012) Chandramouli R. Chillakuri et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Requirement for Dot1l in murine postnatal hematopoiesis and leukemogenesis by MLL translocation

(2011) S. Y. Jo et al.   BLOOD

DOT1L regulates dystrophin expression and is critical for cardiac function

(2011) A. T. Nguyen et al.   GENES & DEVELOPMENT

The diverse functions of Dot1 and H3K79 methylation

(2011) A. T. Nguyen et al.   GENES & DEVELOPMENT

Deficiency of H3K79 Histone Methyltransferase Dot1-like Protein (DOT1L) Inhibits Cell Proliferation

(2011) Wootae Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Notch1 Signaling in FIZZ1 Induction of Myofibroblast Differentiation

(2009) Tianju Liu et al.   AMERICAN JOURNAL OF PATHOLOGY

Lunatic Fringe-mediated Notch signaling is required for lung alveogenesis

(2009) Keli Xu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

DOT1L/KMT4 Recruitment and H3K79 Methylation Are Ubiquitously Coupled with Gene Transcription in Mammalian Cells

(2008) D. J. Steger et al.   MOLECULAR AND CELLULAR BIOLOGY

Combinatorial patterns of histone acetylations and methylations in the human genome

(2008) Zhibin Wang et al.   NATURE GENETICS

Endothelial expression of the Notch ligand Jagged1 is required for vascular smooth muscle development

(2008) F. A. High et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Challenges in pulmonary fibrosis: 8 {middle dot} The need for an international registry for idiopathic pulmonary fibrosis

(2008) J W Wilson et al.   THORAX

Review: New perspectives in the treatment of idiopathic pulmonary fibrosis

(2008) Paola Rogliani et al.   Therapeutic Advances in Respiratory Disease