Curcumin Improves Epithelial Barrier Integrity of Caco-2 Monolayers by Inhibiting Endoplasmic Reticulum Stress and Subsequent Apoptosis

AGA Clinical Practice Guidelines on the Management of Moderate to Severe Ulcerative Colitis

(2020) Joseph D. Feuerstein et al.   GASTROENTEROLOGY

The Integral Role of Tight Junction Proteins in the Repair of Injured Intestinal Epithelium

(2020) Zachary M. Slifer et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Aging Increases the Severity of Colitis and the Related Changes to the Gut Barrier and Gut Microbiota in Humans and Mice

(2020) Ailing Liu et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Colorectal cancer in ulcerative colitis: a Scandinavian population-based cohort study

(2020) Ola Olén et al.   LANCET

Curcumin in Health and Diseases: Alzheimer’s Disease and Curcumin Analogues, Derivatives, and Hybrids

(2020) Eirini Chainoglou et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Curcumin protects murine lung mesenchymal stem cells from H2O2 by modulating the Akt/Nrf2/HO-1 pathway

(2020) Shiwen Ke et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

Curcumin attenuates cytoplasmic/endoplasmic reticulum stress, apoptosis and cholinergic dysfunction in diabetic rat hippocampus

(2020) Walaa A. Keshk et al.   METABOLIC BRAIN DISEASE

Colonic epithelial cell diversity in health and inflammatory bowel disease

(2019) Kaushal Parikh et al.   NATURE

Structural weakening of the colonic mucus barrier is an early event in ulcerative colitis pathogenesis

(2019) Sjoerd van der Post et al.   GUT

Curcumin and Intestinal Inflammatory Diseases: Molecular Mechanisms of Protection

(2019) Kathryn Burge et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Ulcerative Colitis

(2019) Joseph D. Feuerstein et al.   MAYO CLINIC PROCEEDINGS

Efficacy of adjuvant curcumin therapy in ulcerative colitis: A meta‐analysis of randomized controlled trials

(2019) Ting Zheng et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Sirtuin 1 alleviates endoplasmic reticulum stress-mediated apoptosis of intestinal epithelial cells in ulcerative colitis

(2019) Meng-Ting Ren et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Nondysplastic Ulcerative Colitis Has High Levels of the Homologous Recombination Repair Protein NUCKS1 and Low Levels of the DNA Damage Marker Gamma-H2AX

(2018) Paula M De Angelis et al.   INFLAMMATORY BOWEL DISEASES

Overt Increase of Oxidative Stress and DNA Damage in Murine and Human Colitis and Colitis-Associated Neoplasia

(2018) Adrian Frick et al.   MOLECULAR CANCER RESEARCH

Curcumin alleviates DSS-induced colitis via inhibiting NLRP3 inflammsome activation and IL-1β production

(2018) Zizhen Gong et al.   MOLECULAR IMMUNOLOGY

Worldwide incidence and prevalence of inflammatory bowel disease in the 21st century: a systematic review of population-based studies

(2017) Siew C Ng et al.   LANCET

Development of an in vitro co-culture model to mimic the human intestine in healthy and diseased state

(2017) Angela A.M. Kämpfer et al.   TOXICOLOGY IN VITRO

Intestinal Epithelial Cell Endoplasmic Reticulum Stress and Inflammatory Bowel Disease Pathogenesis: An Update Review

(2017) Xiaoshi Ma et al.   Frontiers in Immunology

Curcumin, the golden nutraceutical: multitargeting for multiple chronic diseases

(2016) Ajaikumar B Kunnumakkara et al.   BRITISH JOURNAL OF PHARMACOLOGY

Epithelial ER Stress in Crohnʼs Disease and Ulcerative Colitis

(2016) Stewart S. Cao   INFLAMMATORY BOWEL DISEASES

The intestinal epithelial barrier: a therapeutic target?

(2016) Matthew A. Odenwald et al.   Nature Reviews Gastroenterology & Hepatology

Cross-talk between intestinal epithelial cells and immune cells in inflammatory bowel disease

(2016) Sara Al-Ghadban et al.   Scientific Reports

Curcumin in Combination With Mesalamine Induces Remission in Patients With Mild-to-Moderate Ulcerative Colitis in a Randomized Controlled Trial

(2015) Alon Lang et al.   Clinical Gastroenterology and Hepatology

Cell death induced by endoplasmic reticulum stress

(2015) Raffaella Iurlaro et al.   FEBS Journal

Curcumin ameliorates streptozotocin-induced liver damage through modulation of endoplasmic reticulum stress-mediated apoptosis in diabetic rats

(2015) R. Afrin et al.   FREE RADICAL RESEARCH

Effect of curcumin on p38MAPK expression in DSS-induced murine ulcerative colitis

(2015) C.-P. Li et al.   GENETICS AND MOLECULAR RESEARCH

Endoplasmic Reticulum Stress and Unfolded Protein Response in Inflammatory Bowel Disease

(2015) Stewart S. Cao   INFLAMMATORY BOWEL DISEASES

The Endoplasmic Reticulum Stress Sensor IRE1α in Intestinal Epithelial Cells Is Essential for Protecting against Colitis

(2015) Hai-Sheng Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endoplasmic Reticulum Stress in Intestinal Epithelial Cell Function and Inflammatory Bowel Disease

(2015) Katherine Luo et al.   Gastroenterology Research and Practice

Phosphorylation of eIF2α Is Dispensable for Differentiation but Required at a Posttranscriptional Level for Paneth Cell Function and Intestinal Homeostasis in Mice

(2014) Stewart S. Cao et al.   INFLAMMATORY BOWEL DISEASES

C/EBP homologous protein inhibits tissue repair in response to gut injury and is inversely regulated with chronic inflammation

(2014) N Waldschmitt et al.   Mucosal Immunology

Curcumin ameliorates dextran sulfate sodium-induced experimental colitis by blocking STAT3 signaling pathway

(2013) Liu Liu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Induction with NCB-02 (curcumin) enema for mild-to-moderate distal ulcerative colitis — A randomized, placebo-controlled, pilot study

(2013) Vikas Singla et al.   Journal of Crohns & Colitis

Paneth cells as a site of origin for intestinal inflammation

(2013) Timon E. Adolph et al.   NATURE

Altered Endoplasmic Reticulum Stress Affects Translation in Inactive Colon Tissue From Patients With Ulcerative Colitis

(2011) Xavier Tréton et al.   GASTROENTEROLOGY

Positive Role of CCAAT/Enhancer-Binding Protein Homologous Protein, a Transcription Factor Involved in the Endoplasmic Reticulum Stress Response in the Development of Colitis

(2009) Takushi Namba et al.   AMERICAN JOURNAL OF PATHOLOGY

Prophylactic role of curcumin in dextran sulfate sodium (DSS)-induced ulcerative colitis murine model

(2009) Hossam M.M. Arafa et al.   FOOD AND CHEMICAL TOXICOLOGY

XBP1 Links ER Stress to Intestinal Inflammation and Confers Genetic Risk for Human Inflammatory Bowel Disease

(2008) Arthur Kaser et al.   CELL