YhdP, TamB, and YdbH Are Redundant but Essential for Growth and Lipid Homeostasis of the Gram-Negative Outer Membrane

The Vps13 Family of Lipid Transporters and Its Role at Membrane Contact Sites

(2021) Samantha Katarzyna Dziurdzik et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Transport of lipopolysaccharides and phospholipids to the outer membrane

(2021) Andrew Wilson et al.   CURRENT OPINION IN MICROBIOLOGY

Highly accurate protein structure prediction with AlphaFold

(2021) John Jumper et al.   NATURE

LetB Structure Reveals a Tunnel for Lipid Transport across the Bacterial Envelope

(2020) Georgia L. Isom et al.   CELL

Cryo-EM reconstruction of a VPS13 fragment reveals a long groove to channel lipids between membranes

(2020) PeiQi Li et al.   JOURNAL OF CELL BIOLOGY

Aboard the LetB express

(2020) Matthew J. Powers et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

YejM Modulates Activity of the YciM/FtsH Protease Complex To Prevent Lethal Accumulation of Lipopolysaccharide

(2020) Randi L. Guest et al.   mBio

An Essential Membrane Protein Modulates the Proteolysis of LpxC to Control Lipopolysaccharide Synthesis in Escherichia coli

(2020) Elayne M. Fivenson et al.   mBio

Assembly of Bacterial Capsular Polysaccharides and Exopolysaccharides

(2020) Chris Whitfield et al.   Annual Review of Microbiology

Inter-organelle lipid transfer: a channel model for Vps13 and chorein-N motif proteins

(2020) Joshua A. Lees et al.   CURRENT OPINION IN CELL BIOLOGY

YejM controls LpxC levels by regulating Protease Activity of the FtsH/YciM Complex of Escherichia coli

(2020) Daniel Nguyen et al.   JOURNAL OF BACTERIOLOGY

“Asymmetry is the rhythmic expression of functional design” a quotation from Jan Tschichold

(2020) Joe Lutkenhaus   JOURNAL OF BACTERIOLOGY

Assembly and Maintenance of Lipids at the Bacterial Outer Membrane

(2020) Emily Lundstedt et al.   CHEMICAL REVIEWS

The inner membrane protein YhdP modulates the rate of anterograde phospholipid flow in Escherichia coli

(2020) Jacqueline Grimm et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of VPS13, a protein with similarity to ATG2, in physiology and disease

(2020) Berrak Ugur et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Dynamics of an LPS translocon induced by substrate and an antimicrobial peptide

(2020) Francesco Fiorentino et al.   Nature Chemical Biology

Structural insights into outer membrane asymmetry maintenance in Gram-negative bacteria by MlaFEDB

(2020) Xiaodi Tang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Restoring Balance to the Outer Membrane: YejM’s Role in LPS Regulation

(2020) Brent W. Simpson et al.   mBio

MapB, the Brucella suis TamB homologue, is involved in cell envelope biogenesis, cell division and virulence

(2019) Magalí Graciela Bialer et al.   Scientific Reports

Atg2 mediates direct lipid transfer between membranes for autophagosome formation

(2019) Takuo Osawa et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural basis of unidirectional export of lipopolysaccharide to the cell surface

(2019) Tristan W. Owens et al.   NATURE

ATG2 transports lipids to promote autophagosome biogenesis

(2019) Diana P. Valverde et al.   JOURNAL OF CELL BIOLOGY

ATG2A transfers lipids between membranes in vitro

(2019) Takanori Otomo et al.   Autophagy

Maintaining Integrity Under Stress: Envelope Stress Response Regulation of Pathogenesis in Gram-Negative Bacteria

(2019) Claire L. Hews et al.   Frontiers in Cellular and Infection Microbiology

Salmonella enterica Serovar Typhimurium Uses PbgA/YejM To Regulate Lipopolysaccharide Assembly during Bacteremia

(2019) Melina B. Cian et al.   INFECTION AND IMMUNITY

Lipid trafficking across the Gram-negative cell envelope

(2019) Rahul Shrivastava et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cryo-EM Structure of a Bacterial Lipid Transporter YebT

(2019) Chuan Liu et al.   JOURNAL OF MOLECULAR BIOLOGY

The Complex Rcs Regulatory Cascade

(2018) Erin Wall et al.   Annual Review of Microbiology

Lipopolysaccharide is transported to the cell surface by a membrane-to-membrane protein bridge

(2018) David J. Sherman et al.   SCIENCE

Erratum for May and Silhavy, “The Escherichia coli Phospholipase PldA Regulates Outer Membrane Homeostasis via Lipid Signaling”

(2018) Kerrie L. May et al.   mBio

VPS13A and VPS13C are lipid transport proteins differentially localized at ER contact sites

(2018) Nikit Kumar et al.   JOURNAL OF CELL BIOLOGY

Cyclic Enterobacterial Common Antigen Maintains the Outer Membrane Permeability Barrier of Escherichia coli in a Manner Controlled by YhdP

(2018) Angela M. Mitchell et al.   mBio

The Structure of a Conserved Domain of TamB Reveals a Hydrophobic β Taco Fold

(2017) Inokentijs Josts et al.   STRUCTURE

A tamB homolog is involved in maintenance of cell envelope integrity and stress resistance of Deinococcus radiodurans

(2017) Jiangliu Yu et al.   Scientific Reports

Interrupting Biosynthesis of O Antigen or the Lipopolysaccharide Core Produces Morphological Defects in Escherichia coli by Sequestering Undecaprenyl Phosphate

(2016) Matthew A. Jorgenson et al.   JOURNAL OF BACTERIOLOGY

Novel RpoS-Dependent Mechanisms Strengthen the Envelope Permeability Barrier during Stationary Phase

(2016) Angela M. Mitchell et al.   JOURNAL OF BACTERIOLOGY

The TamB ortholog ofBorrelia burgdorferiinteracts with the β-barrel assembly machine (BAM) complex protein BamA

(2016) Henna Iqbal et al.   MOLECULAR MICROBIOLOGY

ConSurf 2016: an improved methodology to estimate and visualize evolutionary conservation in macromolecules

(2016) Haim Ashkenazy et al.   NUCLEIC ACIDS RESEARCH

Disruption of lipid homeostasis in the Gram-negative cell envelope activates a novel cell death pathway

(2016) Holly A. Sutterlin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effective assembly of fimbriae in Escherichia coli depends on the translocation assembly module nanomachine

(2016) Christopher Stubenrauch et al.   Nature Microbiology

Evolution of the Translocation and Assembly Module (TAM)

(2015) Eva Heinz et al.   Genome Biology and Evolution

Dead-end intermediates in the enterobacterial common antigen pathway induce morphological defects inEscherichia coliby competing for undecaprenyl phosphate

(2015) Matthew A. Jorgenson et al.   MOLECULAR MICROBIOLOGY

The conserved carboxyl domain of MorC, an inner membrane protein ofAggregatibacter actinomycetemcomitans, is essential for membrane function

(2015) K.P. Smith et al.   Molecular Oral Microbiology

Cell age dependent concentration of Escherichia coli divisome proteins analyzed with ImageJ and ObjectJ

(2015) Norbert O. E. Vischer et al.   Frontiers in Microbiology

Ultrastructural Analysis of the Rugose Cell Envelope of a Member of the Pasteurellaceae Family

(2013) F. Azari et al.   JOURNAL OF BACTERIOLOGY

The structural basis of autotransporter translocation by TamA

(2013) Fabian Gruss et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Bacterial lipids: Metabolism and membrane homeostasis

(2013) Joshua B. Parsons et al.   PROGRESS IN LIPID RESEARCH

Dual Molecular Signals Mediate the Bacterial Response to Outer-Membrane Stress

(2013) S. Lima et al.   SCIENCE

Discovery of an archetypal protein transport system in bacterial outer membranes

(2012) Joel Selkrig et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure and Functional Analysis of LptC, a Conserved Membrane Protein Involved in the Lipopolysaccharide Export Pathway inEscherichia coli

(2010) An X. Tran et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Bacterial Cell Envelope

(2010) T. J. Silhavy et al.   Cold Spring Harbor Perspectives in Biology

An ABC transport system that maintains lipid asymmetry in the Gram-negative outer membrane

(2009) J. C. Malinverni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Membrane Morphology and Leukotoxin Secretion Are Associated with a Novel Membrane Protein of Aggregatibacter actinomycetemcomitans

(2008) C. V. Gallant et al.   JOURNAL OF BACTERIOLOGY

Novel Structure of the Conserved Gram-Negative Lipopolysaccharide Transport Protein A and Mutagenesis Analysis

(2008) Michael D.L. Suits et al.   JOURNAL OF MOLECULAR BIOLOGY

Bioinformatics identification of MurJ (MviN) as the peptidoglycan lipid II flippase in Escherichia coli

(2008) N. Ruiz   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA