Article
Agriculture, Multidisciplinary
Fu Yang, Minjie Zhao, Li Zhou, Minghao Zhang, Jikai Liu, Eric Marchioni
Summary: This study characterized and quantified the total lipids of eight wild edible mushrooms, identifying 20 lipid classes and 173 molecular species. Variations in lipid molecules and concentrations among different mushroom species were found, with potential biomarkers such as lysophosphatidylethanolamine (16:1) and ceramide non-hydroxy fatty acid-dihydrosphingosine (d23:0-10:0) identified. The study provides a new perspective for distinguishing mushroom species based on lipidomics.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2021)
Article
Food Science & Technology
Mengwan Li, Ying Shen, Tiejun Ling, Chi-Tang Ho, Daxiang Li, Huimin Guo, Zhongwen Xie
Summary: This study compared the chemical profiles between Zijuan purple tea and Yunkang green tea using metabolomics approach and identified a variety of characteristic metabolites in Zijuan purple tea, with anthocyanins being the most distinctive. Pathway analysis suggested that Zijuan purple tea may generate anthocyanins and proanthocyanins through specific pathways. The study also demonstrated higher concentrations of total anthocyanins in Zijuan purple tea, which correlated with the metabolomics results, providing chemical evidence for the potential health benefits of Zijuan purple tea.
Article
Chemistry, Applied
Chagam Koteswara Reddy, Su Young Son, Choong Hwan Lee
Summary: The study demonstrates that debranched maize starch can form inclusion complexes with catechin-rich green tea ethanolic extract, showing high recovery yield and stability.
FOOD HYDROCOLLOIDS
(2021)
Article
Biochemistry & Molecular Biology
Emily Cioni, Chiara Migone, Roberta Ascrizzi, Beatrice Muscatello, Marinella De Leo, Anna Maria Piras, Ylenia Zambito, Guido Flamini, Luisa Pistelli
Summary: Comparative chemical analyses of peel and pulp extracts from different varieties of Citrus australasica showed variations in composition and antioxidant activity. Collette peel and Pink Ice pulp were rich in flavonoids, while Collette and Red peel exhibited the highest activity in protecting against oxidative damage.
Article
Chemistry, Applied
Rita Cynara de Oliveira Salles, Magno Perea Muniz, Rita de Cassia Saraiva Nunomura, Sergio Massayoshi Nunomura
Summary: This study utilized an untargeted metabolomic analytical method and multivariate analysis to study the chemical composition of guarana produced in the main producing states in Brazil, successfully identifying 13 dimers and trimers of procyanidins type A and B as chemical markers of geographical origin after excluding the influence of catechin and epicatechin, which led to the separation of samples into three main clusters.
Article
Food Science & Technology
Tiehan Li, Shanshan Xu, Yujie Wang, Yuming Wei, Leyi Shi, Zhipeng Xiao, Zhengquan Liu, Wei-Wei Deng, Jingming Ning
Summary: This study analyzed the taste characteristics and chemical profiles of CTC black tea samples from different geographical regions using electronic tongue and mass spectroscopy, identifying potential markers and clarifying the contribution of different metabolites to taste characteristics. The findings provide useful references for future studies on origin traceability and quality characteristic determination of CTC black teas.
JOURNAL OF FOOD SCIENCE
(2021)
Article
Agriculture, Multidisciplinary
Jiaxu Yao, Li Zhou, Yueqi Hu, Minjie Zhao, Yue Ma, Jikai Liu, Eric Marchioni
Summary: Untargeted lipidomics analysis combined with chemometrics was used to identify different mushroom varieties. The extraction efficiency of different solvents for mushroom lipids was compared, and methyl tert-butylether/methanol (2:1, v/v) was found to be the most efficient solvent. Comprehensive lipidomics analysis identified 37 characteristic metabolites that could distinguish between poisonous and edible mushrooms. This study provides a novel method for identifying poisonous mushrooms and a reference for food safety.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Nutrition & Dietetics
Ya Xu, Pu-Lin Liang, Xue-Lian Chen, Ming-Jiong Gong, Liang Zhang, Xiao-Hui Qiu, Jing Zhang, Zhi-Hai Huang, Wen Xu
Summary: This study comprehensively investigated the chemical changes in pu-erh tea after cofermented with Citrus peel using advanced technology, revealing significant chemical profile disparities between Ganpu tea and raw pu-erh tea. The cofermentation process with Citrus peel greatly impacted the content and types of compounds in the tea.
FRONTIERS IN NUTRITION
(2021)
Article
Biochemical Research Methods
I. Vergara-Luis, N. Bocaya, M. Irazola-Dunabeitia, O. Zuloaga, M. Lacuesta, M. Olivares, A. Prieto
Summary: This study aimed to develop an accurate analytical method for the simultaneous analysis of twenty-four antimicrobials in soil, compost, and animal manure samples using ultra-high performance liquid chromatography coupled to a triple-quadrupole mass spectrometer (UHPLC-QqQ). The study evaluated two extraction techniques and thoroughly studied the clean-up step using solid-phase extraction. The method was successfully validated and showed adequate trueness and repeatability.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Wenwen Huang, Zhonglian Zhang, Lu Niu, Xiaohan Hu, Tekleab Teka, Lifeng Han, Guixiang Pan, Qilong Wang
Summary: This study explored the vasorelaxation effects of different species of Uncaria on isolated rat mesenteric artery rings, identified potential vasodilative compounds through metabolite profiling and correlation analysis. The results suggest that metabolomics combined with correlation analysis is an effective strategy for rapidly discovering active compounds in traditional Chinese medicine.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
(2021)
Article
Horticulture
Yun Liu, Fangmeng Zhao, Zheng Zhang, Tian Li, Haipeng Zhang, Juan Xu, Junli Ye, Xiuxin Deng
Summary: The study revealed the structural diversity and tissue distribution of limonoids in pummelo fruit, with seeds containing the most abundant limonoids and the flavedo accumulating fewer major limonoids. Significant positive correlations were found between juice vesicles and seeds, as well as between albedo and segment membranes in limonoid metabolism. The research also identified potential biomarkers for limonoid characterization in different tissues or parts.
SCIENTIA HORTICULTURAE
(2021)
Article
Food Science & Technology
Xinlu Wang, Linxia Wu, Jing Qiu, Yongzhong Qian, Meng Wang
Summary: In this study, non-targeted metabolomics analysis was conducted on 10 strawberry species using UHPLC-Q-Exactive Orbitrap MS. A total of 142 compounds were identified and classified into six categories. Screening 72 differential metabolites revealed that Tochiotome differed the most from the white strawberry (Baiyu). Histidine, apigenin, cyanidin 3-glucoside, and peonidin 3-glucoside were identified as potential biomarkers for distinguishing Baiyu and other strawberry groups. Amino acid metabolism, anthocyanin biosynthesis, and flavonoid biosynthesis pathways played a major role in determining the nutritional distinctions. This research contributes to the determination of the nutrition and health benefits of different strawberry species.
Article
Food Science & Technology
Fanghua Guo, Rong Tsao, Chuyao Li, Xiaoya Wang, Hua Zhang, Li Jiang, Yong Sun, Hua Xiong
Summary: The study found that green pea hull extracts are rich in phenolic substances, such as quercetin, and have significant effects in alleviating DSS-induced colitis.
Article
Biochemistry & Molecular Biology
Yushi Zou, Chen Tang, Xinyu Yang, Tianyang Guo, Huanlu Song
Summary: A study was conducted on the flavor characteristics of different grades of baked green tea. It was found that D-limonene and linalool were identified as odor markers for Grade A tea, while galloylglucose, digalloylglucose, trigalloyglucose, strictinin, and gallic acid were identified as taste markers for Grade A tea. This research reveals the substances responsible for the odor and taste markers of high-grade baked green tea.
Article
Chemistry, Multidisciplinary
Konstantinos M. Kasiotis, Eirini Baira, Styliani Iosifidou, Kyriaki Bergele, Electra Manea-Karga, Ioannis Theologidis, Theodora Barmpouni, Despina Tsipi, Kyriaki Machera
Summary: This study aimed to investigate the chemical, botanical, and physicochemical characteristics of Anama honey. Metabolomics study and melissopalynological analysis were conducted to identify chemical markers and botanical origin of Anama honey, confirming its high quality.
FRONTIERS IN CHEMISTRY
(2022)
Article
Chemistry, Applied
Shuang Liang, Fang Wang, Daniel Granato, Xiaoyu Zhong, An-Feng Xiao, Qun Ye, Lijun Li, Chun Zou, Jun-Feng Yin, Yong-Quan Xu
Summary: The addition of fi-glucosidase can enhance the floral aroma of black tea juice and improve the overall aroma quality, but it can also strengthen the undesirable green grassy odor. The green grassy odor can be counteracted by adding green tea extract. Heat treatment does not significantly affect the stability of aroma components benzyl alcohol and phenylethyl alcohol in the presence of fi-glucosidase.
Article
Food Science & Technology
Cristiane de Moura, Tufy Kabbas Junior, Thiago Mendanha Cruz, Mariza Boscacci Marques, Mariana Araujo Vieira do Carmo, Carolina Turnes Pasini Deolindo, Heitor Daguer, Luciana Azevedo, Yong-Quan Xu, Daniel Granato
Summary: This study examined the influence of solvent polarity in the solid-liquid extraction of Camellia sinensis var. assamica cv. Zijuan. The results showed that a hydroalcoholic extract with a proportion of 75% ethanol and 25% water had the highest contents of phenolic compounds and chlorophylls, as well as the highest color intensity and antioxidant activity.
FOOD RESEARCH INTERNATIONAL
(2023)
Article
Biochemistry & Molecular Biology
Kubra Kizil Ongay, Daniel Granato, George E. Barreto
Summary: Neuroinflammation plays a crucial role in both acute and chronic phases of traumatic brain injury (TBI). This study investigated the antioxidant capacity of apple pomace phenolics, phlorizin and phloretin, and their potential use in TBI treatment. The results showed that phloretin exhibited superior antioxidant properties compared to phlorizin, and both compounds regulated common proteins involved in TBI. It was found that estrogen receptor alpha (ESR1) might be a critical cellular hub regulated by both compounds and could be a potential therapeutic target for TBI.
Article
Food Science & Technology
Yin-feng Ren, Zhi-hao Ye, Xiao-qian Liu, Wei-jing Xia, Yan Yuan, Hai-yan Zhu, Xiao-tong Chen, Ru-yan Hou, Hui-mei Cai, Da-xiang Li, Daniel Granato, Chuan-yi Peng
Summary: In this study, a Surface-enhanced Raman Spectroscopy (SERS) and chemometric-based metabolomics approach was developed to determine the geographic origins of Keemun black tea. SERS peaks enhanced by Ag nanoparticles were selected and intensities were calculated for chemometric analysis. Linear discriminant analysis (LDA) achieved an average discrimination accuracy of 86.3% and cross-validation of 84.3%, while three machine learning algorithms, feedforward neural network (FNN), random forest (RF), and K-Nearest Neighbor (KNN), achieved recognition rates of 93.5%, 93.5%, and 87.1% respectively. This study demonstrates the potential of using SERS technique coupled with AgNPs and chemometrics as a reliable, fast, and convenient method for determining the geographic origins of teas.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2023)
Article
Food Science & Technology
Ana Carolina B. Rezende, Oluwadara Alegbeleye, Syllas Borburema Silva Oliveira, Janio S. Santos, Daniel Granato, Pedro H. C. Felix, Anderson S. St'Ana
Summary: The aim of this study was to determine the growth potential (fi) of Salmonella enterica in different parts (peel, stalk, pulp, and tip) of avocado and sugar apple at various maturation stages (green, mature, and ripe) over time. The physicochemical parameters of the fruits were also monitored. Significant differences were observed in the growth potential of S. enterica in the different parts of the fruits at different maturation stages and over time. The pulp of the fruits exhibited the highest growth potential, with variations depending on the maturation stage and fruit type.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2023)
Article
Food Science & Technology
Nima Mohammadi, Nikoo Ostovar, Daniel Granato
Summary: The study found that P. glabra seed oil is rich in fatty acids, with oleic acid accounting for 52.1% of the total oil, followed by linoleic acid (33.75%) and palmitic acid (6.69%). The oil also has good refractive index and characteristics such as acid value, iodine value, and saponification value. FTIR and DSC analysis revealed the presence of various functional groups and thermal properties. This research provides potential for the development and utilization of P. glabra seed oil.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Qiuyan Ban, Wenjing Chi, Xiaoxiao Wang, Shiqiong Wang, Dan Hai, Guangshan Zhao, Qiuyan Zhao, Daniel Granato, Xianqing Huang
Summary: Increasing evidence suggests that the combination of selenium and polyphenols is a valuable strategy for tumor chemoprevention. A recent study investigated the anti-PC effect of selenium nanoparticles and green tea polyphenol EGCG in mice bearing H22 cells. The results showed that the combination of EGCG and SeNPs could protect against SeNP-triggered diarrhea without compromising the antitumor efficacy of SeNPs.
Article
Medicine, Research & Experimental
Daniel Granato
Summary: Bioactive compounds, such as carotenoids, alkaloids, and phenolics, are widely recognized for their health benefits in a balanced diet. They have various bioactivities, including antioxidant, antihypertensive, antihyperglycemic, antilipidemic, anti-obesity, anti-inflammatory, and antimicrobial effects. In vitro methods have been developed to associate the chemical composition of different sources with their bioactivity, but no single test tube-based assay can predict in vivo responses. Therefore, a cell-based method combining in vitro digestion and absorption is proposed to evaluate the antioxidant capacity of compounds, foods, and nutraceuticals.
BIOMEDICINE & PHARMACOTHERAPY
(2023)
Review
Food Science & Technology
Mingchun Wen, Mengting Zhu, Zisheng Han, Chi-Tang Ho, Daniel Granato, Liang Zhang
Summary: This review summarizes the recent advances in tea metabolomics research. By using different analytical tools, the metabolite variation of tea leaves and the changes of chemical composition under different processing technologies were studied. The importance of metabolite identification process was also discussed.
COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY
(2023)
Article
Food Science & Technology
Amanda dos Santos Lima, Romulo Dias Novaes, Lucas Cezar Pinheiro, Leonardo Augusto de Almeida, Hercia Stampini Duarte Martino, Alexandre Giusti-Paiva, Nora Pap, Daniel Granato, Luciana Azevedo
Summary: This study evaluated the bioactivity and gut microbiota modulation of blackcurrant diets in rats with DMH-induced colon carcinogenesis. The results showed that high doses of blackcurrant increased pro-inflammatory parameters and the expression of anti-apoptotic cytokines, accentuating colon cancer initiation. Additionally, blackcurrant altered the composition and function of the gut microbiome. These findings suggest that high doses of blackcurrant act as a pro-oxidant, exacerbating the inflammatory environment and CRC progression.
FOOD RESEARCH INTERNATIONAL
(2023)
Article
Agricultural Engineering
Abedalghani Halahlah, Felix Abik, Maarit H. Lahtinen, Asmo Kemppinen, Kalle Kaipanen, Petri O. Kilpelainen, Daniel Granato, Thao M. Ho, Kirsi S. Mikkonen
Summary: Softwood galactoglucomannan (GGM) can be recovered through pressurized hot water extraction, membrane filtration, and spray drying, yielding biopolymers suitable for renewable products. The pH and temperature of GGM liquor affect the properties of recovered GGM, and ultrafiltration at pH 10 and 60 degrees C resulted in GGM with unique gel formation capacity suitable for thickening agents or 3D printing.
INDUSTRIAL CROPS AND PRODUCTS
(2023)
Review
Food Science & Technology
Luciana Azevedo, Daniel Granato, Vinicius Maltarollo, Jose E. Goncalves
Summary: Agrifood system technologies have facilitated the creation of innovative foods with improved nutritional profiles. This article provides an overview of the development of food models/prototypes using natural compounds as a source of inspiration, through the integration of various disciplines and food technologies. To create healthy foods, the combination of interrelated technologies from nutrition, chemical synthesis, pharmacology, and food technology with biological system analyses is proposed. Developing food molecules is a slow process that involves mandatory steps based on desired bioactive properties, which is hindered by the diversity of food matrices and the complexity of reconstituting their biosynthetic pathways. Overcoming these challenges should be a primary focus in food science, leading to more sustainable processes and health benefits.
CURRENT OPINION IN FOOD SCIENCE
(2023)
Article
Plant Sciences
Tufy Kabbas Kabbas Junior, Cristiane de Moura, Thiago Mendanha Cruz, Mariza Boscacci Marques, Mariana Araujo Vieira do Carmo, Carolina Turnes Pasini Deolindo, Heitor Daguer, Luciana Azevedo, Daniel Granato
Summary: The aim of this study was to determine the phenolic composition, antioxidant activity, cytotoxicity, and peroxidative inhibition of defatted grape and blackberry seeds. A statistical optimization study was conducted to maximize the extraction of bioactive compounds and antioxidant activity. The extracts showed low/no cytotoxicity, protected against ROS production, and exhibited antioxidant activity and protection on erythrocytes.
Article
Chemistry, Applied
Anica Bebek Markovinovic, Dora Brdar, Predrag Putnik, Tomislav Bosiljkov, Ksenija Durgo, Ana Hudek Turkovic, Irena Brcickaraconji, Karlo Jurica, Branimir Pavlic, Daniel Granato, Danijela Bursac Kovacevic
Summary: This study investigates the use of Arbutus unedo L. fruits for the production of functional foods through three-dimensional printing (3DP). The fruits are found to be a good source of bioactive compounds and antioxidants, with antimicrobial properties. Different printing parameters significantly affect the properties of the 3DP products.
Article
Chemistry, Applied
Marcelo Franchin, Ana Sofia Martelli Chaib Saliba, Alan Giovanini de Oliveira Sartori, Sebastiao Orestes Pereira Neto, Bruna Benso, Masaharu Ikegaki, Kai Wang, Severino Matias de Alencar, Daniel Granato
Summary: Brazilian propolis from Apis mellifera is widely studied for its unique chemical composition and biological properties. This review explores the potential uses of propolis as a functional ingredient in food and pharmaceutical applications, providing a theoretical and practical basis for optimizing its bioactive properties.
