Fine-tuning the spike: role of the nature and topology of the glycan shield in the structure and dynamics of the SARS-CoV-2 S

N- and O-Glycosylation of the SARS-CoV-2 Spike Protein

(2021) Miloslav Sanda et al.   ANALYTICAL CHEMISTRY

Demystifying the momilactone pathway

(2021) Trinh-Don Nguyen et al.   Nature Chemical Biology

Structure, Dynamics, Receptor Binding, and Antibody Binding of the Fully Glycosylated Full-Length SARS-CoV-2 Spike Protein in a Viral Membrane

(2021) Yeol Kyo Choi et al.   Journal of Chemical Theory and Computation

Oligomannose N-Glycans 3D Architecture and Its Response to the FcγRIIIa Structural Landscape

(2021) Carl A Fogarty et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Bat and pangolin coronavirus spike glycoprotein structures provide insights into SARS-CoV-2 evolution

(2021) Shuyuan Zhang et al.   Nature Communications

Structure and binding properties of Pangolin-CoV spike glycoprotein inform the evolution of SARS-CoV-2

(2021) Antoni G. Wrobel et al.   Nature Communications

Multimerization- and glycosylation-dependent receptor binding of SARS-CoV-2 spike proteins

(2021) Kim M. Bouwman et al.   PLoS Pathogens

Site-Specific O-Glycosylation Analysis of SARS-CoV-2 Spike Protein Produced in Insect and Human Cells

(2021) Ieva Bagdonaite et al.   Viruses-Basel

Mapping the SARS-CoV-2 spike glycoprotein-derived peptidome presented by HLA class II on dendritic cells

(2021) Robert Parker et al.   Cell Reports

Native-like SARS-CoV-2 Spike Glycoprotein Expressed by ChAdOx1 nCoV-19/AZD1222 Vaccine

(2021) Yasunori Watanabe et al.   ACS Central Science

Assessing Antigen Structural Integrity through Glycosylation Analysis of the SARS-CoV-2 Viral Spike

(2021) Juliane Brun et al.   ACS Central Science

A selective sweep in the Spike gene has driven SARS-CoV-2 human adaptation

(2021) Lin Kang et al.   CELL

SARS-CoV-2 simulations go exascale to predict dramatic spike opening and cryptic pockets across the proteome

(2021) Maxwell I. Zimmerman et al.   Nature Chemistry

A glycan gate controls opening of the SARS-CoV-2 spike protein

(2021) Terra Sztain et al.   Nature Chemistry

SARS-CoV-2 variants, spike mutations and immune escape

(2021) William T. Harvey et al.   NATURE REVIEWS MICROBIOLOGY

Heparan Sulfate Proteoglycans as Attachment Factor for SARS-CoV-2

(2021) Lin Liu et al.   ACS Central Science

Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation

(2020) Daniel Wrapp et al.   SCIENCE

Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses

(2020) Michael Letko et al.   Nature Microbiology

The spike glycoprotein of the new coronavirus 2019-nCoV contains a furin-like cleavage site absent in CoV of the same clade

(2020) B. Coutard et al.   ANTIVIRAL RESEARCH

Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein

(2020) Alexandra C. Walls et al.   CELL

Cell entry mechanisms of SARS-CoV-2

(2020) Jian Shang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Site-specific glycan analysis of the SARS-CoV-2 spike

(2020) Yasunori Watanabe et al.   SCIENCE

Vulnerabilities in coronavirus glycan shields despite extensive glycosylation

(2020) Yasunori Watanabe et al.   Nature Communications

α-glucosidase inhibitors as host-directed antiviral agents with potential for the treatment of COVID-19

(2020) Spencer J. Williams et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

SARS-CoV-2 and bat RaTG13 spike glycoprotein structures inform on virus evolution and furin-cleavage effects

(2020) Antoni G. Wrobel et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2

(2020) Thomas Mandel Clausen et al.   CELL

Molecular Architecture of the SARS-CoV-2 Virus

(2020) Hangping Yao et al.   CELL

Virus-Receptor Interactions of Glycosylated SARS-CoV-2 Spike and Human ACE2 Receptor

(2020) Peng Zhao et al.   Cell Host & Microbe

SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies

(2020) Christopher O. Barnes et al.   NATURE

Analysis of the SARS-CoV-2 spike protein glycan shield reveals implications for immune recognition

(2020) Oliver C. Grant et al.   Scientific Reports

Beyond Shielding: The Roles of Glycans in the SARS-CoV-2 Spike Protein

(2020) Lorenzo Casalino et al.   ACS Central Science

The SARS-COV-2 Spike Protein Binds Sialic Acids and Enables Rapid Detection in a Lateral Flow Point of Care Diagnostic Device

(2020) Alexander N. Baker et al.   ACS Central Science

Heparin Inhibits Cellular Invasion by SARS-CoV-2: Structural Dependence of the Interaction of the Spike S1 Receptor-Binding Domain with Heparin

(2020) Courtney J. Mycroft-West et al.   THROMBOSIS AND HAEMOSTASIS

Exploitation of glycosylation in enveloped virus pathobiology

(2019) Yasunori Watanabe et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

High-throughput characterization of the functional impact of IgG Fc glycan aberrancy in juvenile idiopathic arthritis

(2017) Hao D Cheng et al.   GLYCOBIOLOGY

Tectonic conformational changes of a coronavirus spike glycoprotein promote membrane fusion

(2017) Alexandra C. Walls et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen

(2017) Jesper Pallesen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure, Function, and Evolution of Coronavirus Spike Proteins

(2016) Fang Li   Annual Review of Virology

Cell entry of enveloped viruses

(2011) Richard K Plemper   Current Opinion in Virology