The phosphodiesterase 4 inhibitor roflumilast augments the Th17-promoting capability of dendritic cells by enhancing IL-23 production, and impairs their T cell stimulatory activity due to elevated IL-10

Published 2016 View Full Article

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Title
The phosphodiesterase 4 inhibitor roflumilast augments the Th17-promoting capability of dendritic cells by enhancing IL-23 production, and impairs their T cell stimulatory activity due to elevated IL-10
Authors
Keywords
cAMP, PDE4, PKA, Dendritic cells, IL-17, T cells
Journal
INTERNATIONAL IMMUNOPHARMACOLOGY
Volume 35, Issue -, Pages 174-184
Publisher
Elsevier BV
Online
2016-04-18
DOI
10.1016/j.intimp.2016.03.025

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