The phosphodiesterase 4 inhibitor roflumilast augments the Th17-promoting capability of dendritic cells by enhancing IL-23 production, and impairs their T cell stimulatory activity due to elevated IL-10

标题
The phosphodiesterase 4 inhibitor roflumilast augments the Th17-promoting capability of dendritic cells by enhancing IL-23 production, and impairs their T cell stimulatory activity due to elevated IL-10
作者
关键词
cAMP, PDE4, PKA, Dendritic cells, IL-17, T cells
出版物
INTERNATIONAL IMMUNOPHARMACOLOGY
Volume 35, Issue -, Pages 174-184
出版商
Elsevier BV
发表日期
2016-04-18
DOI
10.1016/j.intimp.2016.03.025

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