Sirtuin 5-Mediated Lysine Desuccinylation Protects Mitochondrial Metabolism Following Subarachnoid Hemorrhage in Mice

Optogenetic translocation of protons out of penumbral neurons is protective in a rodent model of focal cerebral ischemia

(2020) Bin Bo et al.   Brain Stimulation

An optimized desuccinylase activity assay reveals a difference in desuccinylation activity between proliferative and differentiated cells

(2020) Taolin Yuan et al.   Scientific Reports

Succinylation Links Metabolism to Protein Functions

(2019) Yun Yang et al.   NEUROCHEMICAL RESEARCH

MicroRNA-132 attenuates cerebral injury by protecting blood-brain-barrier in MCAO mice

(2019) Xiaokun Zuo et al.   EXPERIMENTAL NEUROLOGY

The NAD+-Dependent Family of Sirtuins in Cerebral Ischemia and Preconditioning

(2018) Nathalie Khoury et al.   ANTIOXIDANTS & REDOX SIGNALING

Metabolomics Based Identification of SIRT5 and Protein Kinase C Epsilon Regulated Pathways in Brain

(2018) Kevin B. Koronowski et al.   Frontiers in Neuroscience

The Acute Phase of Experimental Subarachnoid Hemorrhage: Intracranial Pressure Dynamics and Their Effect on Cerebral Blood Flow and Autoregulation

(2018) Catharina Conzen et al.   Translational Stroke Research

Thioredoxin-Interacting Protein Mediates Apoptosis in Early Brain Injury after Subarachnoid Haemorrhage

(2017) Qing Zhao et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Acidosis Drives the Reprogramming of Fatty Acid Metabolism in Cancer Cells through Changes in Mitochondrial and Histone Acetylation

(2016) Cyril Corbet et al.   Cell Metabolism

Inhibition of stress fiber formation preserves blood–brain barrier after intracerebral hemorrhage in mice

(2016) Anatol Manaenko et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Roles of Hippocampal Somatostatin Receptor Subtypes in Stress Response and Emotionality

(2016) Thomas D Prévôt et al.   NEUROPSYCHOPHARMACOLOGY

Metabolomics-assisted proteomics identifies succinylation and SIRT5 as important regulators of cardiac function

(2016) Sushabhan Sadhukhan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lipoxin A4 Reduces Inflammation Through Formyl Peptide Receptor 2/p38 MAPK Signaling Pathway in Subarachnoid Hemorrhage Rats

(2016) Zongduo Guo et al.   STROKE

Protein Kinase C Epsilon Promotes Cerebral Ischemic Tolerance Via Modulation of Mitochondrial Sirt5

(2016) Kahlilia C. Morris-Blanco et al.   Scientific Reports

SIRT5 regulation of ammonia-induced autophagy and mitophagy

(2015) Lucia Polletta et al.   Autophagy

Effect of resveratrol on sirtuins expression and cardiac complications in diabetes

(2015) Pankaj K. Bagul et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Sirtuins and the Metabolic Hurdles in Cancer

(2015) Natalie J. German et al.   CURRENT BIOLOGY

Characterization of the cardiac succinylome and its role in ischemia–reperfusion injury

(2015) Jennifer A. Boylston et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The deacetylase Sirt1 is an essential regulator of Aire-mediated induction of central immunological tolerance

(2015) Anna Chuprin et al.   NATURE IMMUNOLOGY

Effect of Decompressive Craniectomy on Outcome Following Subarachnoid Hemorrhage in Mice

(2015) Dominik Bühler et al.   STROKE

The SIRT1/HIF2  Axis Drives Reductive Glutamine Metabolism under Chronic Acidosis and Alters Tumor Response to Therapy

(2014) C. Corbet et al.   CANCER RESEARCH

Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS

(2014) Edward T. Chouchani et al.   NATURE

SIRT5 Regulates the Mitochondrial Lysine Succinylome and Metabolic Networks

(2013) Matthew J. Rardin et al.   Cell Metabolism

SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways

(2013) Jeongsoon Park et al.   MOLECULAR CELL

A Molecular Mechanism for Direct Sirtuin Activation by Resveratrol

(2012) Melanie Gertz et al.   PLoS One

Brain Lactate Metabolism in Humans With Subarachnoid Hemorrhage

(2012) Mauro Oddo et al.   STROKE

Measurement of H2O2 within Living Drosophila during Aging Using a Ratiometric Mass Spectrometry Probe Targeted to the Mitochondrial Matrix

(2011) Helena M. Cochemé et al.   Cell Metabolism

Sirt5 Is a NAD-Dependent Protein Lysine Demalonylase and Desuccinylase

(2011) J. Du et al.   SCIENCE

Cerebral Perfusion Pressure Thresholds for Brain Tissue Hypoxia and Metabolic Crisis After Poor-Grade Subarachnoid Hemorrhage

(2011) J. Michael Schmidt et al.   STROKE