Profile‐likelihood Bayesian model averaging for two‐sample summary data Mendelian randomization in the presence of horizontal pleiotropy

Selecting likely causal risk factors from high-throughput experiments using multivariable Mendelian randomization

(2020) Verena Zuber et al.   Nature Communications

Statistical inference in two-sample summary-data Mendelian randomization using robust adjusted profile score

(2020) Qingyuan Zhao et al.   ANNALS OF STATISTICS

Two robust tools for inference about causal effects with invalid instruments

(2020) Hyunseung Kang et al.   BIOMETRICS

Powerful three-sample genome-wide design and robust statistical inference in summary-data Mendelian randomization

(2019) Qingyuan Zhao et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Evaluating the potential role of pleiotropy in Mendelian randomization studies

(2018) Gibran Hemani et al.   HUMAN MOLECULAR GENETICS

Modal-based estimation via heterogeneity-penalized weighting: model averaging for consistent and efficient estimation in Mendelian randomization when a plurality of candidate instruments are valid

(2018) Stephen Burgess et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Improving the visualization, interpretation and analysis of two-sample summary data Mendelian randomization via the Radial plot and Radial regression

(2018) Jack Bowden et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Confidence intervals for causal effects with invalid instruments by using two-stage hard thresholding with voting

(2018) Zijian Guo et al.   JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY

Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases

(2018) Marie Verbanck et al.   NATURE GENETICS

A new perspective on lipid research in age-related macular degeneration

(2018) Elisabeth M. van Leeuwen et al.   PROGRESS IN RETINAL AND EYE RESEARCH

The MR-Base platform supports systematic causal inference across the human phenome

(2018) Gibran Hemani et al.   eLife

An examination of multivariable Mendelian randomization in the single-sample and two-sample summary data settings

(2018) Eleanor Sanderson et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Increased High-Density Lipoprotein Levels Associated with Age-Related Macular Degeneration

(2018) Johanna M. Colijn et al.   OPHTHALMOLOGY

A Bayesian approach to Mendelian randomisation with dependent instruments

(2018) Chin Yang Shapland et al.   STATISTICS IN MEDICINE

Robust inference in summary data Mendelian randomization via the zero modal pleiotropy assumption

(2017) Fernando Pires Hartwig et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Mendelian Randomization Implicates High-Density Lipoprotein Cholesterol–Associated Mechanisms in Etiology of Age-Related Macular Degeneration

(2017) Stephen Burgess et al.   OPHTHALMOLOGY

A framework for the investigation of pleiotropy in two-sample summary data Mendelian randomization

(2017) Jack Bowden et al.   STATISTICS IN MEDICINE

Mendelian randomization incorporating uncertainty about pleiotropy

(2017) John R. Thompson et al.   STATISTICS IN MEDICINE

Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study

(2017) James P. Davis et al.   PLoS Genetics

Contrasting the Genetic Architecture of 30 Complex Traits from Summary Association Data

(2016) Huwenbo Shi et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Consistent Estimation in Mendelian Randomization with Some Invalid Instruments Using a Weighted Median Estimator

(2016) Jack Bowden et al.   GENETIC EPIDEMIOLOGY

Mendelian Randomization using Public Data from Genetic Consortia

(2016) John R. Thompson et al.  

Commentary: Two-sample Mendelian randomization: opportunities and challenges

(2016) Debbie A Lawlor   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA

(2016) Johannes Kettunen et al.   Nature Communications

Mendelian Randomization using Public Data from Genetic Consortia

(2016) John R. Thompson et al.   International Journal of Biostatistics

Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression

(2015) J. Bowden et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants

(2015) Lars G Fritsche et al.   NATURE GENETICS

Detecting pleiotropy in Mendelian randomisation studies with summary data and a continuous outcome

(2015) Fabiola Del Greco M et al.   STATISTICS IN MEDICINE

Mendelian Randomization Analysis With Multiple Genetic Variants Using Summarized Data

(2013) Stephen Burgess et al.   GENETIC EPIDEMIOLOGY

Bayesian model averaging in the instrumental variable regression model

(2012) Gary Koop et al.   JOURNAL OF ECONOMETRICS