Article
Materials Science, Multidisciplinary
Baoling Li, Yabing Gan, Ke Yang, E. Pang, Xiaojie Ren, Shaojing Zhao, Dan He, Fuwen Zhao, Benhua Wang, Peng Yin, Xiangzhi Song, Minhuan Lan
Summary: This study designed and synthesized a molecular structure for multidimensional imaging-guided photodynamic/photothermal therapy. The resultant nanoparticle possesses NIR absorption, photoacoustic imaging, NIR-II fluorescence imaging capabilities, as well as the ability to generate singlet oxygen, hydroxyl radicals, and heat simultaneously.
SCIENCE CHINA-MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Xiaoming Hu, Zejing Chen, Albert J. Jin, Zhen Yang, Deqiang Gan, Aifang Wu, Haiyong Ao, Wei Huang, Quli Fan
Summary: This study develops a novel all-organic nanotheranostic platform that combines magnetic resonance imaging and near-infrared fluorescence imaging for precise tumor locating and treatment.
Article
Chemistry, Analytical
Tan Tai Nguyen, Nguyen Van Sau, Quang Minh Ngo, Gauthier Eppe, Ngoc Quyen Tran, Nguyen Thi Phuong Anh
Summary: The multilayer of the surface plasmon resonance (SPR) sensor was optimized to achieve the maximum sensor sensitivity. The optimized sensor showed high detection accuracy and sensitivity, indicating potential applications in the field of biological diagnosis.
Article
Chemistry, Multidisciplinary
Mengyuan Li, Zhuoting Lu, Jiaxin Zhang, Liying Chen, Xialian Tang, Quanheng Jiang, Qinglian Hu, Lin Li, Jie Liu, Wei Huang
Summary: This study reports the use of an organic fluorescent substance AS1, which has fluorescence, photothermal, and photodynamic functions in the near-infrared II window. The encapsulation of AS1 into nanostructures results in high-performance phototheranostics (AS1R) with superior brightness, photothermal effect, and photodynamic performance compared to other types of organic phototheranostics.
ADVANCED MATERIALS
(2023)
Article
Nanoscience & Nanotechnology
Mingming Yin, Junwei Tong, Fanling Meng, Chenchen Liu, Xiaoming Liu, Fang Fang, Zhenyan He, Xiaojuan Qin, Chengbo Liu, Dong Ni, Yuting Gao, Huageng Liang, Xiaoping Zhang, Liang Luo
Summary: This study demonstrates the development of a symbiotic 2D nanohybrid that combines carbon nanomaterials and clay nanomaterials for synergistic cancer therapy and diagnosis. The nanohybrid exhibits high photothermal conversion efficiency and the ability to generate reactive oxygen species, allowing for simultaneous photothermal therapy, chemodynamic therapy, and photoacoustic/magnetic imaging for precision nanomedicine.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Nanoscience & Nanotechnology
Venkatarao Selamneni, Abhishek Mukherjee, Harini Raghavan, P. Thanga Gomathi, Chandra Sekhar Reddy Kolli, Subhradeep Pal, Arnab Hazra, Parikshit Sahatiya
Summary: The study demonstrated a flexible and high-performance broadband plasmonic photodetector by integrating gold nanoparticles on 2D ReS2 nanosheets, showing significantly enhanced photo detection performance. The device exhibited good photoresponsivity in the visible and near-infrared regions, with a response speed of approximately 200 ms.
ACS APPLIED NANO MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Ying Zhang, Qi Shen, Qi Li, Panpan He, Jinyan Li, Feng Huang, Jing Wang, Yefan Duan, Chuang Shen, Faisal Saleem, Zhimin Luo, Lianhui Wang
Summary: This study discovered ultrathin two-dimensional plasmonic PtAg nanosheets with strong broadband light absorption from NIR-I to NIR-II biowindow, exhibiting outstanding photothermal and photoacoustic effects under both 785 and 1064 nm lasers. Functionalized PtAg nanosheets showed good biocompatibility and tumor-targeted function in vivo, achieving effective tumor ablation through photoacoustic imaging (PAI) and photothermal therapy (PTT).
Article
Thermodynamics
Md Anwar Jahid, Julian Wang, Enhe Zhang, Qiuhua Duan, Yanxiao Feng
Summary: This study proposes a new concept of dynamic windows that utilize nanoscale solar infrared-induced plasmonic photothermal effects for reversible solar heat modulation independent of visible light conditions. Analytical models validated through experiments demonstrate the technical characteristics and thermal and optical features of these reversible photothermal windows under solar irradiation. Whole building energy simulations show that these windows have the potential to save over 18% energy in mixed climates compared to baseline models built using the most recent energy efficiency standards.
ENERGY CONVERSION AND MANAGEMENT
(2022)
Review
Chemistry, Multidisciplinary
Hangqi Luo, Shuai Gao
Summary: Phototherapy, including photothermal therapy (PTT) and photodynamic therapy (PDT), is widely used for cancer treatment, but conventional PTT/PDT lack disease recognition ability, resulting in limited therapeutic effects. Integrating fluorescence imaging with PTT/PDT can reveal tumor locations in real-time, enabling early diagnosis and precision treatment. The use of NIR-II fluorescence imaging with PTT/PDT can significantly improve tumor theranostics accuracy and minimize damage to normal tissues.
JOURNAL OF CONTROLLED RELEASE
(2023)
Review
Chemistry, Physical
Jorge Becerra, Vishnu Nair Gopalakrishnan, Toan-Anh Quach, Trong-On Do
Summary: Solar-light harvesting materials, particularly those involving plasmonic metals, are currently a hot topic in catalysis. By coupling plasmonic metal nanoparticles with semiconductor materials, unique synergistic effects and properties can be achieved. Reticular materials, such as metal organic frameworks, play a key role in generating these plasmonic nanocomposites and enhancing their performance in various applications.
Article
Chemistry, Multidisciplinary
Kihoon Kim, Zachary M. Sherman, Angela Cleri, Woo Je Chang, Jon-Paul Maria, Thomas M. Truskett, Delia J. Milliron
Summary: By continuously varying doping at two length scales, the atomic and nanocrystal scales, the frequency and bandwidth of the collective plasmon resonance in nanocrystal-based metasurfaces can be tuned, leading to the emergence of a broad infrared spectral region with near-zero permittivity. This multiscale doping strategy offers a powerful approach to designing metamaterials for optical applications.
Article
Chemistry, Multidisciplinary
Wanting He, Chuanshuang Chen, Yannan Liu, Alessandro Tomasino, S. Shayan Mousavi Masouleh, Jesus Valdez, Tugrul Guner, Roberto Morandotti, Audrey Moores, Gianluigi A. Botton, Yongfeng Zhou, Aycan Yurtsever, Dongling Ma
Summary: In this study, plasmonic polymeric nanoassemblies consisting of a self-assembled polymer vesicle and a gold nanoparticle were synthesized, and the hydrogen generation efficiency was increased by 8 times compared to nonplasmonic vesicles. The properties of the heterodimer were investigated at the single particle level using advanced transmission electron microscopes, including one equipped with a femtosecond pulsed laser. These findings provide guidance for designing new hybrid nanostructures for plasmon-related applications.
Review
Chemistry, Multidisciplinary
Tingjun Yan, Mengyao Su, Zhimin Wang, Jiatao Zhang
Summary: This review introduces the application of plasmonic nanomaterials with modulated optical properties in photothermal therapy and photoacoustic imaging. These nanomaterials have tunable optical properties and strong light absorption, showing great potential in phototheranostics.
Article
Nanoscience & Nanotechnology
Jinchang Yin, Hongting Zheng, Anming Li, Jintao Zhang, Li Tian, Fuli Zhao, Yuanzhi Shao
Summary: A new type of UCPL nanoprobe, Au nanospheres assemblage@Gd2O3:Yb3+/Ln(3+), was reported with emission enhancements ranging from 46 to 96-fold compared to its Au-free counterparts. The aggregation and interaction of Au nanospheres inside the nanoprobe resulted in the presence of three characteristic LSPR peaks in visible and near-infrared regions, intensifying both excitation and emission fields throughout the nanoprobe. This study demonstrated a synchronous double-field-enhanced upconversion of the optical nanoprobe in situ, shedding light on the mechanism underlying LSPR-induced UCPL enhancement.
Article
Chemistry, Physical
Xuejian Xing, Ke Yang, Baoling Li, Siyi Tan, Jianing Yi, Xiangcao Li, E. Pang, Benhua Wang, Xiangzhi Song, Minhuan Lan
Summary: Regulating the photochemical properties of phototheranostics, such as absorption, fluorescence, singlet oxygen generation, and photothermal conversion efficiency, is a popular research topic. By designing and synthesizing boron dipyrromethene (BODIPY) derivatives, the absorption and fluorescence in the near-infrared region can be significantly improved. Coating these hydrophobic BODIPYs with DSPE-PEG-2000 allows for the formation of water dispersible nanoparticles (NPs), which can be used for NIR fluorescent and photoacoustic imaging-guided photodynamic and photothermal therapy of cancer.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2022)
Article
Chemistry, Multidisciplinary
Guangzhi Zhou, Ming Li
Summary: This study presents a plasmonic trienzyme-integrated metal-organic framework (plasEnMOF) nanoplatform for synergistic therapy of hypoxic tumors. The encapsulation of NIR-II plasmonic Au nanorods and natural enzymes allowed for efficient depletion of intratumoral glucose and generation of toxic reactive oxygen species for cancer therapy.
ADVANCED MATERIALS
(2022)
Article
Nanoscience & Nanotechnology
Huyun Liu, Renting Jiang, Yaxuan Lu, Beibei Shan, Yu Wen, Ming Li
Summary: In this study, a biodegradable a-CFT@IP6@BSA agent was developed for efficient cancer therapy. The agent can release plenty of Cu+ ions in a tumor-specific manner and utilize them for the production of hydroxyl radicals. It also depletes intracellular GSH to protect the hydroxyl radicals from scavenging. The treatment with a-CFT@IP6@BSA nanoparticles leads to the downregulation of glutathione peroxidase 4 and BCL-2, indicating the induction of ferroptosis and apoptotic death of cancer cells. The nanoparticles also demonstrate excellent anticancer efficiency in vivo and have the potential for imaging-guided cancer treatment.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Chemistry, Analytical
Yangcenzi Xie, Yu Wen, Xiaoming Su, Chao Zheng, Ming Li
Summary: A machine learning-driven surface-enhanced Raman spectroscopy (SERS)-integrated strategy is developed for label-free detection of cellular HER2, achieving high accuracy in cell identification and classification for HER2+ breast cancer. The combination of label-free SERS detection and machine learning-driven analysis enables longitudinal monitoring of therapeutic efficacy, aiding in decision-making and management.
ANALYTICAL CHEMISTRY
(2022)
Article
Multidisciplinary Sciences
Linhu Li, Renting Jiang, Beibei Shan, Yaxuan Lu, Chao Zheng, Ming Li
Summary: Researchers report a class of porous nanostructures composed of cubic AuAg alloy nanoshell and numerous nanopores. These porous nanostructures exhibit excellent plasmonic properties in the near-infrared II spectral range, which can be tuned by varying the pore features. Near-infrared II SERS probes created with these porous cubic AuAg nanoshells demonstrate remarkable capability for in vivo visualization of sub-millimeter microtumors in a living mouse model.
NATURE COMMUNICATIONS
(2022)
Article
Engineering, Environmental
Guangzhi Zhou, Ming Li
Summary: This study reports a new type of Cu2-xTe nanosheets that can be degraded by gluta-thione, which can effectively treat cancer through mild-photothermally enhanced chemodynamic therapy. The results show that the nanosheets have excellent plasmonic absorption and photothermal properties, and can efficiently catalyze the production of & BULL;OH in cancer cells. The study demonstrates the potential of these nanosheets as a potent CDT agent for efficient cancer treatment.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Chemistry, Physical
Mingyang Chen, Renata Solarska, Ming Li
Summary: Despite progress, precise evaluation of the surface-enhanced Raman scattering (SERS) substrate enhancement factor (EF) still remains unresolved. This study emphasizes the importance of probe molecules in terms of diffusion kinetics and surface coverage for accurate determination of the SERS EFs, which has not been addressed in previous research.
JOURNAL OF PHYSICAL CHEMISTRY C
(2023)
Article
Nanoscience & Nanotechnology
Bin Meng, Yong Xie, Le Chen, Haitao Wang, Ming Li, Zhuxin Dong
Summary: This paper presents a convenient technical scheme for enhancing the performance of atomic force microscopy (AFM) tips in tip-enhanced Raman spectroscopy (TERS) applications. The silver decoration on homemade tips is confined to the apex of commercial tips through an AFM-controlled electrochemical reaction. The efficiency of the metal coating is ensured by the reduction of Ag+ in a highly sealed environment. Key factors affecting the process include the use of silver nitrate solution, ambient relative humidity and temperature, electric potential bias, and tip-surface distance. The silver-coated tips are then tested for TERS measurement of carbon nanotubes (CNTs), resulting in simultaneous characterization of the CNTs' morphology and chemical properties. The Raman spectra show that our plasmonic tip exhibits a local field signal increase of approximately 30-fold, and the corresponding TERS image can resolve at the single-pixel level laterally.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Multidisciplinary
Xiaoming Su, Xinyu Liu, Yangcenzi Xie, Mingyang Chen, Chao Zheng, Hong Zhong, Ming Li
Summary: Researchers have developed a paper-based biosensor using surface-enhanced Raman spectroscopy for quantitative analysis of exosomal proteins in clinical serum samples, which allows for accurate diagnosis and molecular subtyping of breast cancer.
Article
Chemistry, Analytical
Xiaoming Su, Xinyu Liu, Yangcenzi Xie, Mingyang Chen, Hong Zhong, Ming Li
Summary: The widespread abuse of fentanyl has become a major global public health concern, leading to a drastic increase in overdose deaths. A recently developed freestanding surface-enhanced Raman spectroscopy (SERS) biosensor, called the FrEnSERS biosensor, has shown excellent capability in identifying and quantifying trace amounts of fentanyl in biofluids. This biosensor, composed of a reduced graphene oxide membrane decorated with hydrophobic Au nanostars, combines high SERS enhancement and analyte enrichment to achieve remarkable SERS performance. It has demonstrated sensitive and quantitative detection of fentanyl in serum and urine, with a wide dynamic range and low limits of detection. The FrEnSERS biosensor is a promising tool for forensic analysis and clinical diagnosis, providing a sensitive, cost-effective, and reliable method for rapid quantitative analysis of fentanyl in biofluids.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Physical
Haitao Wang, Huiming Zhang, Beibei Shan, Renata Solarska, Ming Li
Summary: This study numerically investigates the plasmonic and photothermal properties of Au-silica-Cu2-x Se hybrid nanoshells (Cu2-x Se HNSs) with varied core offsets. The plasmon modes in the symmetry-broken Cu2-x Se HNSs are explained by plasmon hybridization theory. The results show tunability of NIR-II thermoplasmonic properties in the Cu2-x Se HNSs through varying the core offset.
JOURNAL OF PHYSICAL CHEMISTRY C
(2023)
Article
Chemistry, Physical
Huiming Zhang, Ting Zhu, Ming Li
Summary: In this study, the photothermal effects of Au nanoparticles (NPs) of different shapes were systematically investigated. It was found that the photothermal properties of Au NPs are closely related to their geometric shape and localized surface plasmon resonance (LSPR) wavelength. Specifically, Au NPs with sharp structural features such as Au nanorod, nanostar, and nanobipyramid exhibited exceptional light-to-heat conversion ability, indicated by their larger Joule (Jo) number.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2023)
Article
Nanoscience & Nanotechnology
Xiaoming Su, Yangcenzi Xie, Xinyu Liu, Mingyang Chen, Chao Zheng, Hong Zhong, Ming Li
Summary: Quantitative analysis of serum exosomes was performed using surface-enhanced Raman spectroscopy (SERS) combined with a paper-based lateral flow strip (LFS) biosensor and multivariate spectral unmixing analysis. This technique allowed for absolute quantification of two different serum exosomes with a detection limit of 10(6) particles/mL. The strategy was successfully applied in the quantitative dual-plex detection of serum exosomes from breast cancer patients.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Multidisciplinary
Renting Jiang, Linhu Li, Ming Li
Summary: A degradable DNAzyme biocapsule has been developed for efficient gene therapy of breast cancer. The biocapsule effectively downregulates EGR-1 and Bcl-2 protein expression, inducing apoptosis in tumor cells. This study provides a promising strategy for constructing degradable DNAzyme-based platforms for effective gene therapy of metastatic breast cancer.
Article
Chemistry, Multidisciplinary
Yangcenzi Xie, Mingyang Chen, Xinyu Liu, Xiaoming Su, Ming Li
Summary: An artificial intelligence-assisted label-free surface-enhanced Raman spectroscopy (SERS) biosensor is developed for simultaneous quantification of C-5-methylcytosine (C-5m) level and methylation ratio in DNA samples.
ADVANCED FUNCTIONAL MATERIALS
(2023)