Article
Chemistry, Analytical
Yinan Zeng, Min Zhang, Kefu Peng, Zu Man, Lu'an Guo, Wenping Liu, Shilei Xie, Peng Liu, Dong Xie, Shoushan Wang, Faliang Cheng
Summary: A photoelectrochemical molecular imprinting sensor based on Au/TiO2 nanocomposite was developed for the detection of dibutyl phthalate (DBP). Through the growth of TiO2 nanorods by hydrothermal method and electrodeposition of gold nanoparticles on TiO2, the Au/TiO2 composite was fabricated. Then, a molecular imprinted polymer (MIP) was electropolymerized on the Au/TiO2 surface to enhance the photoelectric conversion efficiency and sensitivity of the sensor. The MIP also provided highly selective recognition sites for DBP molecules. The sensor exhibited a wide linear range, low limit of detection, and good selectivity, showing promising applications in environmental analysis.
Article
Electrochemistry
Ying Chen, Xi Li, Guoneng Cai, Meijin Li, Dianping Tang
Summary: The (001)TiO2/Ti3C2 heterojunctions were successfully fabricated and used as an electrode material for the photoelectrochemical (PEC) detection of dopamine, showing promising potential for applications in PEC detection.
ELECTROCHEMISTRY COMMUNICATIONS
(2021)
Article
Electrochemistry
Masanobu Higashi, Takumi Toyodome, Koya Kano, Yutaka Amao
Summary: In this study, a hybrid system consisting of CdS photoanode, lactate dehydrogenase (LDH), and Rh complex [Cp*Rh(bpy)(H2O)]2+ was developed as a catalyst for photoelectrochemical lactate production. Through in situ NADH regeneration using a reversible electron donor [Fe(CN)6]4-, the reduction efficiency of pyruvate to lactate was estimated to be 22.8% with an average production rate of 8.6 μmol/h under visible light irradiation, without applied bias and toxic substances.
ELECTROCHIMICA ACTA
(2023)
Article
Chemistry, Multidisciplinary
Caiyan Lai, Bingdong Yan, Run Yuan, Delun Chen, Xiaohong Wang, Mingyu Wang, Heyu He, Jinchun Tu
Summary: In this study, a heterojunction composed of a TiO2 nanosheet and layered Ti3C2 was synthesized. The TiO2/Ti3C2 composites exhibited increased surface area and extended light absorption range, leading to prolonged lifetime of photogenerated carriers. A photoelectrochemical DNA biosensor based on the TiO2/Ti3C2 heterostructure was constructed and comprehensively studied. The sensor displayed stability and sensitivity for DNA detection in the range of 10 nM-10 fM, with a lower detection limit of 6 fM. It provided potential for early diagnosis of various diseases by detecting target DNA.
Article
Materials Science, Ceramics
Xiaohong Zhang, Zuobao Yang, Jiahui Zhou, Weijie Lu, Liangfeng Yang
Summary: A well-defined TiO2 hierarchical nanostructure was successfully constructed through in-situ transformation of TiO2 nanoparticles. This nanostructure exhibited enhanced light harvesting and lower recombination rate, leading to significantly improved photoelectrochemical performance.
CERAMICS INTERNATIONAL
(2023)
Article
Chemistry, Analytical
Dongwei Feng, Peng Huang, Yunfei Miao, Axin Liang, Xuan Wang, Bo Tang, Huipeng Hou, Mingxing Ren, Shimeng Gao, Lina Geng, Aiqin Luo
Summary: Developing cost-effective, ease-to-use, and sensitive cholesterol sensors is crucial. Photoelectrochemical (PEC) sensors have shown potential with their low cost, simple instrumentation, easy miniaturization, and high sensitivity. However, the extreme sensitivity of organometal lead halide perovskites (MAPbX3) has limited their application in biological use. In this study, a novel MAPbX3 photoelectrochemical cholesterol sensor with water stability was developed, exhibiting super sensitivity and selectivity for cholesterol detection in aqueous samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Biophysics
Yukun Yang, Wenyan Yan, Xiaomin Wang, Ligang Yu, Jinhua Zhang, Baoqing Bai, Caixia Guo, Sanhong Fan
Summary: A novel MIP-PEC sensor based on MOFs and TiO2 was established for ultrasensitive and selective detection of OTC. The sensor showed enhanced photocurrent response and improved selectivity and sensitivity due to the use of MOFs and MIP. This sensor provides a new approach for the detection of pollutants in food safety using MOFs in PEC sensors.
BIOSENSORS & BIOELECTRONICS
(2021)
Article
Chemistry, Analytical
Sethupathi Velmurugan, Thomas C-K Yang, Jyy-Ning Chen, Liu Zhi-Xiang
Summary: The synthesis of eco-friendly metal oxide pn junction composite with high visible light absorption and its photoelectrochemical monitoring on antibiotics were reported. The In2O3-CuO pn heterojunction composite exhibited high conductivity and stability for the detection of ornidazole, with a detection limit of 0.0092 nM. The sensor device showed practical applicability in various samples with recoveries above 95%, validated against electrochemical methods.
Article
Engineering, Electrical & Electronic
Cecilia I. Vazquez, Felipe Montero Bruni, Ana Maria Baruzzi, Rodrigo A. Iglesias
Summary: A non-enzymatic photoelectrochemical method using a CdS|TiO2 nanotubes photoanode is proposed for the detection of aqueous sulfide and ascorbic acid. The sensitivity of both the CdS|TiO2 and CdS|Pt photoanodes is high in the visible range, allowing for detection at micromolar levels for sulfide and ascorbic acid. However, the detection of H2O2 leads to the degradation of CdS and the release of Cd2+ ions into the analyte solution.
IEEE SENSORS JOURNAL
(2023)
Article
Chemistry, Physical
Penghui Yan, Xinxin Tian, Eric M. Kennedy, Michael Stockenhuber
Summary: This study investigates the hydrodeoxygenation (HDO) of anisole over Ni/SiO2 catalysts, and explores the correlation between catalyst properties and reaction mechanism. The results show that the Ni/SiO2 catalyst exhibits strong hydrogenolysis activity for anisole, promoting the formation of condensed-ring products.
JOURNAL OF CATALYSIS
(2023)
Article
Chemistry, Multidisciplinary
Monika Soltys-Mroz, Karolina Syrek, Lukasz Pieta, Kamilla Malek, Grzegorz D. Sulka
Summary: In this study, Fe2O3-TiO2 materials were synthesized by cathodic electrochemical deposition, and the effect of hematite content on the photoelectrochemical activity of the materials was investigated. The results showed that the amount of deposited iron and hematite content increased with deposition time, directly impacting the semiconducting properties and enhancing the photoelectrochemical water oxidation and visible light response of the materials.
Article
Electrochemistry
Xuliang Pang, Hongye Bai, Yong Zhao, Lingling Qu, Dongbo Xu, Jinrui Ding, Weiqiang Fan, Weidong Shi
Summary: A sensitive/visible light-driven PEC sensor system was established for selectively detecting 4-NP using a Ni/Cu2O photocathode. The Ni/Cu2O photocathode exhibited excellent PEC reduction capacity for ultra-sensitive sensing of trace amounts of 4-NP under illumination.
ELECTROCHIMICA ACTA
(2021)
Article
Chemistry, Multidisciplinary
Guo-Na Huo, Sha-Sha Zhang, Yue-Liu Li, Jia-Xing Li, Zhao Yue, Wei-Ping Huang, Shou-Min Zhang, Bao-Lin Zhu
Summary: Heterojunction structures formed by TiO2 nanotubes can enhance the photoelectric properties by preventing the recombination of electron-hole pairs. A CdS-TiO2NTs photoelectrochemical sensor was fabricated using the hydrothermal-impregnation method, showing good PEC performance under visible light.
Article
Materials Science, Multidisciplinary
Tongle Gao, Ting-Ting Li, Xilin Liao, Jia-Horng Lin, Bing-Chiuan Shiu, Ching-Wen Lou
Summary: In this study, a non-enzymatic glucose sensor based on Cu2O/TiO2 heterojunction was successfully constructed. The sensor exhibited a wide linear response range and low detection limit, along with good selectivity, stability, and reproducibility. The heterojunction construction provided new ideas and possibilities for preparing photoelectrode materials.
JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T
(2022)
Article
Chemistry, Analytical
Xiaoqing Zhang, Tianning Li, Xuening Gao, Jingwen Lin, Baizhao Zeng, Chuqing Gong, Faqiong Zhao
Summary: In this study, a molecularly imprinted photoelectrochemical (PEC) sensor was developed for the detection of chlortetracycline (CTC) using a sensitized ZnO-MWCNTs-NH2 electrode. The sensor exhibited good sensitivity and selectivity towards CTC, and could be used for the detection of CTC in actual samples.
MICROCHEMICAL JOURNAL
(2023)
Article
Nanoscience & Nanotechnology
Jose L. Bott-Neto, Thiago S. Martins, Lorenzo A. Buscaglia, Sergio A. S. Machado, Osvaldo N. Jr Jr Oliveira
Summary: A photoelectrochemical (PEC) device was developed for detecting prostate-specific antigen (PSA) with high sensitivity under visible LED light. The device showed a 3.1-fold increase in photocurrent compared to pure TiO2 and could detect PSA with high accuracy in human serum samples.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Nanoscience & Nanotechnology
Matheus B. C. de Souza, Katia-Emiko Guima, Pablo S. Fernandez, Caue A. Martins
Summary: By modifying the Pt/C/CP anode with Bi in situ or in operando, glycerol conversion and power output can be improved while reducing the formation of carbonyl compounds. The low CO poisoning of the anode leads to a more complete glycerol electrooxidation reaction, harvesting more electrons at the device.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Nanoscience & Nanotechnology
Thiago S. Martins, Jose L. Bott-Neto, Sergio A. S. Machado, Osvaldo N. Oliveira Jr
Summary: In this study, flexible and fully printed immunosensor chips with tree-like gold dendrites were successfully fabricated using electrodeposition. The optimized molecular architectures of the immunosensors exhibited high sensitivity and stability, enabling accurate detection of metabolites in human samples.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Chemistry, Physical
Jose L. Bott Neto, Thiago S. Martins, Sergio A. S. Machado, Osvaldo N. Oliveira Jr
Summary: In this study, a miniaturized PEC system with enhanced catalytic activity of Au NPs decorated CN was used to detect the breast cancer biomarker CA15-3. The performance of the immunosensor was influenced by the size of the nanoparticles and the film architecture. Optimization of the sensing method allowed for effective detection of CA15-3.
APPLIED SURFACE SCIENCE
(2022)
Article
Chemistry, Physical
Hui Luo, Victor Y. Yukuhiro, Pablo S. Fernandez, Jingyu Feng, Paul Thompson, Reshma R. Rao, Rongsheng Cai, Silvia Favero, Sarah J. Haigh, James R. Durrant, Ifan E. L. Stephens, Maria-Magdalena Titirici
Summary: PtNi2 catalyst with a moderate Ni content and a homogenously alloyed structure exhibited the highest reaction activity in the electrochemical oxidation of glycerol among all materials studied. The role of Ni in PtNi is to tailor the electronic structure of pure Pt sites, influencing the glycerol oxidation reaction.
Article
Chemistry, Physical
Gabriela Soffiati, Victor Y. Yukuhiro, Swathi P. Raju, Matheus B. C. De Souza, Leonardo Marquezini, Edison Z. da Silva, Pablo S. Fernandez, Miguel A. San-Miguel
Summary: We demonstrate that Pt(111) and Pt(100) can catalyze the oxidation of the secondary carbon of polyols to produce ketones. The addition of Bi increases the selectivity for ketone formation. In contrast, pure and Bi-modified Pt(110) only yield C3 molecules with oxidation on the primary carbon, but Bi modification enhances the activity. DFT calculations suggest that positively charged Bi adatoms facilitate the oxidation of the secondary carbon in the enediol-like intermediate, leading to the production of DHA.
Review
Chemistry, Applied
Murilo M. Amaral, Carla G. Real, Victor Y. Yukuhiro, Gustavo Doubek, Pablo S. Fernandez, Gurpreet Singh, Hudson Zanin
Summary: This article provides a comprehensive overview of the applications of in situ and operando infrared spectroscopy in lithium-ion batteries and other battery systems. These techniques can identify the formation of species during electrolyte reduction, electrode degradation, and the formation of the solid-electrolyte interphase (SEI) layer, and serve as a protocol to address remaining issues in batteries.
JOURNAL OF ENERGY CHEMISTRY
(2023)
Article
Chemistry, Physical
Patricia V. B. Santiago, Swathi P. Raju, Karthik Akkiraju, Rafael A. Vicente, Mariane A. da Silva, Shuai Yuan, Daniela Zanchet, Yang Shao-Horn, Pablo S. Fernandez
Summary: The cost-effective production of green hydrogen is a significant challenge for sustainable energy transition. Overcoming obstacles to decrease the cost of hydrogen production through electrolysis, such as developing more active and stable anodes made of abundant and cheap materials. The substitution of biomass-derived substances for the oxidation of water at the anode of electrolyzers can decrease power input and potentially generate value-added chemicals.
ACS APPLIED ENERGY MATERIALS
(2023)
Article
Chemistry, Analytical
Rafael Alcides Vicente, Swathi Patchaiammal Raju, Heloisa Vampre Nascimento Gomes, Itamar Tomio Neckel, Helio Cesar Nogueira Tolentino, Pablo Sebastian Fernandez
Summary: Real electrocatalysts are heterogeneous and their activity depends on specific active sites. Spatially resolved techniques can characterize different regions of catalysts. Spectroelectrochemical cells enable obtaining X-ray and vibrational spectroscopy contrast images, facilitating complete analysis of catalyst performance.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Applied
Thiago S. Martins, Sergio A. S. Machado, Osvaldo N. Oliveira Jr, Jose L. Bott-Neto
Summary: We report on paper-based electrochemical sensors made with screen-printed carbon electrodes for the detection of the fungicide carbendazim. The sensors on kraft paper treated in an acidic medium showed the highest performance, with a detection limit of 0.06 μM. The enhanced sensitivity of the sensor was attributed to the porous nature of kraft paper and the carboxylic groups formed during electrochemical activation. As a proof-of-concept, the sensor attached to the skin of apple and cabbage demonstrated the ability to detect carbendazim with the same performance as the gold standard method.
Article
Materials Science, Multidisciplinary
Luiz Gustavo Bonato, Guilherme Dal Poggetto, Raphael Fernando Moral, Brener Rodrigo de Carvalho Vale, Jose Carlos Germino, Diogo Burigo Almeida, Patricia Santiago, Pablo Sebastian Fernandez, Claudio Francisco Tormena, Lazaro A. Padilha, Ana Flavia Nogueira
Summary: In this study, the influence of organic ligands on the photostability of CsPbBr3 perovskite nanocrystals was investigated. The results demonstrate that alkylphosphate ligands can improve the photostability of colloidal nanocrystals dispersions, which is important for applications requiring continuous excitation.
JOURNAL OF MATERIALS CHEMISTRY C
(2023)
Article
Chemistry, Physical
Bruno L. da Silva, Saulo A. Carminati, Matheus B. C. Souza, Leonardo C. Soares, Claudia Longo, Pablo S. Fernandez, Ana F. Nogueira
Summary: A low-cost, stable, and non-toxic Bi2Fe4O9 (BFO) photoanode was used to promote the photoelectrochemical conversion of glycerol aqueous solution to hydrogen and value-added chemicals. The best performance was achieved in alkaline medium, while poorer performance was observed in acidic and neutral mediums. The main limitation of BFO is electron-hole recombination, but its high open circuit potential (OCP) and other desirable properties make it a material worth further research.
SUSTAINABLE ENERGY & FUELS
(2023)
Article
Chemistry, Physical
Jose L. Bott-Neto, Thiago S. Martins, Osvaldo N. Oliveira, Frank Marken
Summary: This study presents a PEC platform based on TiO2 electrodeposition onto printed carbon electrodes, which eliminates the need for heat treatment. The resulting electrodes show higher photocurrents and improved sensitivity and selectivity for detecting ascorbic acid. The use of brookite TiO2 nanocrystals allows for the production of miniaturized devices for sensitive, selective PEC (bio)sensors.
APPLIED SURFACE SCIENCE
(2023)
Article
Nanoscience & Nanotechnology
Thiago S. Martins, Jose L. Bott-Neto, Sergio A. S. Machado, Osvaldo N. Oliveira
Summary: This article introduces a flexible and fully printed immunosensor with optimized molecular structures and working conditions, which achieves high sensitivity for metabolite detection. The sensor is stable, reproducible, and unresponsive to interference from other molecules. It can also be used as a wearable sensor with mechanical flexibility and customization.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Chemistry, Analytical
Mengmeng Guo, Na Luo, Yueling Bai, Zhenggang Xue, Qingmin Hu, Jiaqiang Xu
Summary: A porous heterostructure WO3-C/In2O3 was designed and prepared for a miniature H2 sensor, which showed higher response value, lower operating temperature, fast response-recovery speed, and low limit of detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Feng Hu, Hui Hu, Yuting Li, Xiaohui Wang, Xiaowen Shi
Summary: Arsenic contamination in water bodies is a significant health risk. This study developed a chitosan-catechol modified electrode for rapid and accurate detection of trace amounts of arsenic. The modified electrode demonstrated good detection capability and resistance to ionic interference, making it suitable for in situ detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yantao Zhang, Qian Liu, Tao Tian, Chunhua Xu, Pengli Yang, Lianju Ma, Yi Hou, Hui Zhou, Yongjun Gan
Summary: In this study, a lysosome-targeting buffering fluorogenic probe (Lyso-BFP) was designed and synthesized, demonstrating excellent photostability, pH specificity, and responsiveness to lysosomal acidification in living cells. The performance of Lyso-BFP in pH sensing was attributed to the inhibition of the photo-induced electron transfer process. Lyso-BFP allowed for wash-free imaging and long-term real-time monitoring of lysosome pH changes based on its off-on fluorescence behavior and buffer strategy.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Wei Cai, Wenbo Sun, Jiayue Wang, Xiaokui Huo, Xudong Cao, Xiangge Tian, Xiaochi Ma, Lei Feng
Summary: In this study, a near-infrared fluorescent probe HCBG was developed for imaging of alpha-GLC. HCBG exhibited excellent selectivity and sensitivity towards alpha-GLC in complex bio-samples, and showed good cell permeability for in situ real-time imaging. Through the high-throughput screening system established by HCBG, a natural alpha-GLC inhibitor was successfully isolated and identified. This study provides a novel fluorescence visualization tool for discovering and exploring the biological functions of diabetes-related gut microbiota, and a high-throughput screening approach for alpha-GLC inhibitor.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Trey W. Pittman, Xi Zhang, Chamindie Punyadeera, Charles S. Henry
Summary: Heart failure is a growing epidemic and a significant clinical and public health problem. Researchers have developed a portable and affordable diagnostic device for heart failure that can be used at the point-of-care, providing a valid alternative to current diagnostics approaches.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Anders O. Tjell, Barbara Jud, Roland Schaller-Ammann, Torsten Mayr
Summary: An optical hydrogen peroxide sensor based on catalytic degradation and the detection of produced oxygen is presented. The sensor offers higher resolution and better sensitivity at lower H2O2 concentrations. By removing O2 from the sample solution, a more sensitive O2 sensor can be used for measurement. The sensor has been successfully applied in a flow-through cell to measure H2O2 concentration in different flow rates.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Seong Jae Kim, Ji-hun Jeong, Gaabhin Ryu, Yoon Sick Eom, Sanha Kim
Summary: Surface-enhanced Raman spectroscopy (SERS) is a high-sensitivity, label-free detection method with various analytical applications. Researchers have developed a hydrophobic SERS substrate based on engineered carbon nanotube arrays (CNT-SERS) and studied the role of structural design at both micro and nanoscales. The substrate demonstrated controlled self-enrichment capability and enhanced sensitivity, with a significant increase in the SERS signal. The study also proposed a theoretical model and a concentration strategy inspired by plants for analyte deposition on microarrays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Dan Zhao, Renjun Jiang, Xiaoqiang Liu, Subbiah Alwarappan
Summary: In this study, a novel ternary composite material was constructed by assembling cerium vanadate nanorods on reduced graphene oxide-microcrystalline cellulose nanosheets, and it was used for real-time monitoring of the concentration of superoxide anions in vivo. The ternary composite showed excellent conductivity, large surface area, and abundant active sites, leading to a wider linear range, high sensitivity, low detection limit, and fast response time for superoxide anion detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Tengfei Wang, Liwen Wang, Guang Wu, Dating Tian
Summary: In this study, a covalent organic framework material TaTp-COF with porous and uniform spheres was successfully prepared via hydrothermal reaction, and it was found to significantly enhance the aggregation-induced emission (AIE) of berberine. The unique emission properties of berberine on TaTp-COF were studied and utilized for the sensitive detection of berberine.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Lin Li, Yilei Ding, Lei Xu, Shuoran Chen, Guoliang Dai, Pengju Han, Lixin Lu, Changqing Ye, Yanlin Song
Summary: In this study, a novel TTI based on a ratiometric fluorescent nanosensor is designed, which has the advantages of high accuracy and low cost. Experimental and theoretical investigations confirm its pH responsiveness and demonstrate its good sensitivity and reliability. By monitoring the total volatile basic nitrogen, this TTI can accurately predict food spoilage and can be adaptively modified for different types of food. The TTI based on this nanosensor enables visual monitoring of food quality.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Fangju Chen, Xueting Wang, Wei Chen, Chenwen Shao, Yong Qian
Summary: Lung cancer is the second most common malignant tumor worldwide. Drug resistance in lung cancer leads to treatment failure and recurrence in majority of patients. This study developed a fluorescent prodrug that can be activated in cancer cells to release drugs, and its signal can be tracked by imaging. It shows a unique autophagy-driven ferroptosis effect, indicating its potential for targeting drug-resistant cancer cells.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Weichao Li, Qiming Yuan, Zhangcheng Xia, Xiaoxue Ma, Lifang He, Ling Jin, Xiangfeng Chu, Kui Zhang
Summary: This study developed a high-performance gas sensor for formaldehyde detection by modifying ZnSnO3 with ZnO QDs and SnO2 QDs. The modified sensor showed improved sensing response and lower working temperature. The presence of ZnO QDs formed rich heterojunctions, increased surface area, and provided oxygen deficiency for formaldehyde sensing reaction, thus enhancing the sensor performance. This research provides an alternative method to enhance the sensing properties of MOS by QDs modification.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Joung-Il Moon, Eun Jung Choi, Younju Joung, Jin-Woo Oh, Sang-Woo Joo, Jaebum Choo
Summary: A novel nanoplasmonic substrate was developed for biomedical applications, which showed strong hot spots for detecting biomarkers at low concentrations. The substrate, called AuNPs@M13, was made by immobilizing 60 nm gold nanoparticles onto the surface of an M13 bacteriophage scaffold. It demonstrated higher sensitivity and lower limit of detection compared to commercially available assays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Ning Li, Ya Zhang, Ying Xu, Xiaofang Liu, Jian Chen, Mei Yang, Changjun Hou, Danqun Huo
Summary: The molecular subtype of breast cancer guides treatment and drug selection. Invasive tests can promote cancer cell metastasis, so the development of high-performance, low-cost diagnostic tools for cancer prognosis is crucial. Liquid biopsy techniques enable noninvasive, real-time, dynamic, multicomponent, quantitative, and long-term observations at the cellular, genetic, and molecular levels. A Cu-Zr metal-organic framework (MOF) nanoenzyme with monatomic Cu attachment has been synthesized and proven to have high catalytic performance. The sensor constructed using this nanoenzyme shows potential for accurate classification of breast cancer serum samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Jeongmin Kim, Hyemin Kim, Seunghyun Park, Hyeonaug Hong, Yong Jae Kim, Jiyong Lee, Jaeho Kim, Seung-Woo Cho, Wonhyoung Ryu
Summary: This study presents a method to fabricate independently functioning microneedle (MN) electrodes with narrow intervals for high precision electrochemical sensing. The optimized mixture of photocurable polymer and single-wall carbon nanotubes was used to mold single composite MNs, which were then attached to pre-patterned electrodes. Plasma etching and electropolymerization were performed to enhance the electrochemical activity, and Prussian blue and glucose oxidase were electrodeposited on the MNs for glucose detection. The MN electrodes showed good sensitivity and linearity, and the feasibility of glucose detection was demonstrated in an in vivo mouse study.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
