Article
Chemistry, Analytical
Yongying Li, Haibo Liang, Bixia Lin, Ying Yu, Yumin Wang, Li Zhang, Yujuan Cao, Manli Guo
Summary: A novel ratiometric fluorescence strategy based on g-CNQD and the PA complex formed between PBA and ARS is proposed for detection of AChE. The method showed good linear relationship with AChE concentration and was successfully applied for determination of AChE in human serum and screening of inhibitors.
Article
Biochemical Research Methods
Hanqiang Zhang, Yufei Li, Haixin Lu, Feng Gan
Summary: A new dual-mode ratiometric fluorescence and colorimetric probe has been developed for selective determination of Cu2+. The probe shows high accuracy and sensitivity, and has immense potential for practical applications.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2022)
Article
Engineering, Electrical & Electronic
Pedro Conceicao, Joana F. B. Barata, Miguel A. Hernandez-Rodriguez, Paula S. S. Lacerda, Maria G. P. M. S. Neves, Lus D. Carlos, Tito Trindade
Summary: This work presents an example of luminescent ratiometric thermal sensor using 5,10,15,20-tetrakis(pentafluorophenyl)porphyrin (TPFPP) and colloidal ZnS/AOT quantum dots (QDs). The nanoassemblies prepared based on the inner filter effect showed good temperature reversibility and a maximum relative thermal sensitivity of 0.95%°C-1 at 50°C.
SENSORS AND ACTUATORS A-PHYSICAL
(2023)
Article
Chemistry, Analytical
Chunran Ma, Peihua Li, Lian Xia, Fengli Qu, Rong-Mei Kong, Zhi-Ling Song
Summary: A novel ratiometric fluorescence nanoprobe based on carbon dots and Cu nanoclusters was developed for the label-free determination of uric acid. The nanoprobe achieved sensitive detection of uric acid in human urine samples by quantifying H2O2 levels, providing a convenient method for uric acid analysis.
Article
Chemistry, Analytical
Ming Han, Yi Wang, Gang Xiang, Yinyin Chen, Zhouping Yang, Yunchun Li, Yu Zhang, Changfang Lu, Xianxiang Wang
Summary: A nanocomposite-based dual-emission fluorescent probe was developed for detecting ethylene thioureas (ETU). The probe consisted of sulfur quantum dots (SQDs) and gluta-thione stabilized gold clusters (GSH-AuNCs). The fluorescence intensities at 450 nm and 570 nm decreased due to aggregation fluorescence quenching, but the addition of ETU resulted in a partial recovery of fluorescence at 570 nm. The method showed high selectivity and sensitivity, and had good recovery of ETU in agricultural products.
MICROCHEMICAL JOURNAL
(2023)
Article
Materials Science, Multidisciplinary
Fanyong Yan, Yueyan Zang, Jingxia Xu, Shan Guan, Li Chen, Jingru Sun
Summary: In this study, highly stable blue luminescent sulfur quantum dots (beta-SQDs) were synthesized rapidly using sublimated sulfur as the sulfur source and beta-cyclodextrin as the passivator. The incorporation of beta-cyclodextrin regulated the size and dispersion of beta-SQDs, enhancing their luminescence properties. The beta-SQDs showed satisfactory accuracy and recovery in the detection of real samples, indicating their potential role in environmental analysis.
MATERIALS RESEARCH BULLETIN
(2022)
Article
Spectroscopy
Chunling Yuan, Xiu Qin, Yuanjin Xu, Rui Shi, Shiqi Cheng, Yilin Wang
Summary: Fluorescent carbon quantum dots with excitation-dependent emission characteristics were successfully prepared, exhibiting peroxidase-like activity and potential applications in detecting H2O2 and uric acid.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Article
Chemistry, Analytical
Zeming Huang, Yin Gao, Zhengyu Huang, Donglin Chen, Jiahui Sun, Li Zhou
Summary: Exploring an effective sensor for detecting Fe3+ and phytic acid (PA) is crucial for human health, and a metal-free fluorescent nanoprobe based on sulfur quantum dots (SQDs) has been developed for this purpose. The SQDs show responsive and selective fluorescence behavior towards Fe3+ and PA, with a good linear relationship and low limits of detection. The sensor was successfully used to detect PA in fresh carrot and lettuce samples.
MICROCHEMICAL JOURNAL
(2021)
Article
Chemistry, Applied
Yuerui Zhuang, Bixia Lin, Ying Yu, Yumin Wang, Li Zhang, Yujuan Cao, Manli Guo
Summary: This study developed a ratiometric fluorescent probe based on sulfur quantum dots and Ca2+ for the detection of doxycycline residue, showing a good linear relationship and low detection limit. The method also achieved visual semiquantitative detection of doxycycline and yielded good recoveries in milk and fish samples. It demonstrates great potential for detecting doxycycline in food samples.
Article
Chemistry, Analytical
Anqi Huang, Xiaofang Yang, Ting Xia, Daichun He, Rui Zhang, Zongtao Li, Shengchun Yang, Yong Liu, Xiaodong Wen
Summary: A sulfur quantum dots fluorescent probe was developed for rapid and sensitive detection of excessive copper ion residue in traditional Chinese medicine. The probe showed excellent stability, high selectivity, and satisfactory results in the detection of actual samples.
MICROCHEMICAL JOURNAL
(2022)
Article
Spectroscopy
Xiaoping Chen, Jianwei Lin, Yafeng Zhuang, Siqi Huang, Jinghua Chen, Zhizhong Han
Summary: A new ratiometric fluorescence sensor is developed for the selective detection of chlorotetracycline (CTC) using dual-mode fluorescence method, demonstrating good selectivity and sensitivity.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Chemistry, Analytical
Qiuzheng Du, Wenjun Guo, Yingying Shi, Ziwei Jing, Zhi Sun
Summary: Exploring highly sensitive fluorescent strategies for the determination of uric acid (UA) is crucial for early diagnosis of hyperuricemia. A simple and highly sensitive ratiometric fluorescence sensor based on boric acid-functionalized lanthanide metal-organic framework (BA-EuMOF) was constructed for UA determination in complex environments. The BA-EuMOF sensor displayed a wide linear range and low detection limit, exhibiting satisfactory photostability, sensitivity, and anti-interference capability. This sensor has been successfully applied to UA determination in urine, providing a reference for UA detection in complex clinical systems.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Applied
Fanyong Yan, Jingru Sun, Yueyan Zang, Zhonghui Sun, Hao Zhang, Jinxia Xu, Xiang Wang
Summary: Nitrogen-doped MQDs derived from MXene exhibit excellent photoluminescent properties and have the potential for effective detection of Alizarin Red. They are expected to have further applications in the fields of environmental monitoring and biosensing.
Article
Chemistry, Analytical
Xuanxuan An, Ruchun Chen, Qizhen Chen, Qin Tan, Shuang Pan, Hui Liu, Xiaoli Hu
Summary: A MnO2 nanosheet-assisted ratiometric fluorescence probe has been developed for the detection of the anticancer drug 6-mercaptopurine. The probe shows considerable sensitivity and good selectivity, making it suitable for the detection of 6-MP in human serum samples and pharmaceutical tablets.
Article
Biophysics
Yongqiang Shi, Lei Lin, Yuzhen Wei, Wenting Li, Pengcheng Nie, Yong He, Xuping Feng
Summary: A novel ratiometric aptasensor was developed using CQDs@ZIF8 and Apt-AuNPs for highly sensitive detection of ABA. The sensor showed increased sensitivity and selectivity in detecting ABA levels in rice seeds, offering a new strategy for ultra-sensitive measurement of biomolecules.
BIOSENSORS & BIOELECTRONICS
(2021)
Article
Chemistry, Organic
Jia-Bao Liu, Haidar Ali, Muhammad Kashif Shafiq, Ghulam Dustigeer, Parvez Ali
Summary: The research focuses on the applications of topological indices in analyzing the bio-compatibility of chemical compounds in the context of QSAR and QSPR correlations. By combining Chemistry and Graph theory, Chemical graph theory deals with topology and plays a significant role in the development of topological indices. The article specifically explores the use of degree based topological indices in Octahedron networks.
POLYCYCLIC AROMATIC COMPOUNDS
(2023)
Article
Substance Abuse
Neal Shah, Matthew Nali, Cortni Bardier, Jiawei Li, James Maroulis, Raphael Cuomo, Tim K. Mackey
Summary: This study used unsupervised machine learning to analyze the sales of electronic nicotine delivery systems (ENDS) on Instagram. The results showed that there is a significant amount of unregulated ENDS sales on Instagram, including flavored products, and many websites lack age verification. These findings may violate Instagram's policies and US laws, highlighting the need for stronger regulation to prevent youth access to and use of ENDS.
Article
Computer Science, Artificial Intelligence
Lingbo Liu, Zewei Yang, Guanbin Li, Kuo Wang, Tianshui Chen, Liang Lin
Summary: This paper discusses an important task in land remote-sensing analysis, which is the automatic extraction of traffic roads from remote-sensing data. To address this problem, the authors introduce a novel neural network framework that utilizes the complementary information from different data sources to enhance the accuracy and robustness of road extraction.
IEEE TRANSACTIONS ON NEURAL NETWORKS AND LEARNING SYSTEMS
(2023)
Article
Biochemical Research Methods
Yan Yan, Jiaxing Liu, Min Zhang, Yinjie Zhang, Biyun Shi, Xuemei Qin, Chenhui Du
Summary: In this study, quality markers for Ziziphi Spinosae semen (ZSS) were proposed using a combination of metabolic in vivo study and network pharmacology. An UHPLC-Q-Orbitrap-MS method was used to identify and assign components in ZSS, and metabolic networks of flavonoids, saponins, and alkaloids were established. Twelve key bioactive components against insomnia were selected as quality markers for ZSS.
BIOMEDICAL CHROMATOGRAPHY
(2023)
Article
Cell Biology
Nan Shan Zhong, Wei Lai Tong, Yu Zhang, Shi Ning Xiao, Jia Ming Liu, An An Li, Ge Liang Yao, Qing Lin, Zhi Li Liu
Summary: HELQ plays a tumor-suppressive role in non-small-cell lung cancer and has the potential to be a predictive biomarker for prognosis and treatment of lung cancer.
CELL BIOLOGY INTERNATIONAL
(2023)
Article
Materials Science, Paper & Wood
Jianjun Gu, Xiaofei Yan, Dongming Qi, Ruyi Xie, Xiaoming Yang, Yaobang Li, Jiawei Li
Summary: In this study, a durable multifunctional coating was successfully fabricated on cotton fabric, providing it with flame retardant, antibacterial, superhydrophobic and self-cleaning properties. The coated fabric exhibited excellent durability even after multiple washing cycles.
Article
Gastroenterology & Hepatology
Jingxian Hu, Miao Jiang, Hongyan Liu, Hao Zhou, Yajie Wang
Summary: The study finds that endoscopic purse-string sutures appear to be safe and effective in the treatment of high-risk peptic ulcer hemorrhage patients.
SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY
(2023)
Review
Materials Science, Textiles
Shifeng Wu, Jiawei Li, Chongwen Yu
Summary: This paper proposes a simulation method for the fiber arrangement in slub yarn and uses the finite element method to simulate the twist distribution of slub yarn, which is consistent with actual spinning results. The research is significant for further exploration of the properties of slub yarn.
TEXTILE RESEARCH JOURNAL
(2023)
Review
Chemistry, Multidisciplinary
Jianming Yang, Xin Yan, Xinru Xu, Yujian Chen, Wei Han, Xianzhi Chai, Xiang Liu, Jiaxing Liu, Chen Liu, Hexin Zhang, Xiao Li, Zhen Zhang, Tie Wang
Summary: Polymeric electromagnetic interference (EMI) shielding materials based on CO2 foaming technology have gained widespread attention due to their efficient use of CO2, high strength, corrosion resistance, and low cost. New design concepts and preparation techniques have led to the development of high-performance EMI shielding materials. This review summarizes the progress made in fabricating EMI shielding composite foams using supercritical carbon dioxide (scCO(2)) foaming and explores the relationship between component/distribution and EMI shielding properties. Additionally, it discusses the application prospects and development challenges of new EMI shielding composite foams.
CHEMISTRY-AN ASIAN JOURNAL
(2023)
Article
Computer Science, Interdisciplinary Applications
Jiawei Li, Pavel Tomin, Hamdi Tchelepi
Summary: There is an increasing interest in developing robust and efficient sequential methods for reservoir simulation. The sequential fully implicit Newton (SFIN) method addresses the slow sequential coupling convergence issue when flow and transport problems are strongly coupled. However, the original SFIN algorithm requires fixed primary variables during the simulation. In this work, strategies are proposed to handle inconsistent primary variables and extend the SFIN method to the natural black-oil formulation.
COMPUTATIONAL GEOSCIENCES
(2023)
Article
Dentistry, Oral Surgery & Medicine
Taotao Zhang, Kuan Yang, Yujiang Chen, Yuran Jiang, Zhifei Zhou, Jiajia Liu, Yang Du, Lulu Wang, Xinxin Han, Xingan Wu, Xiaojing Wang
Summary: This study found that nicotine treatment impairs autophagy function in periodontal ligament stem cells, leading to the production of inflammatory factors. Activation of α7nAChR by nicotine upregulates NEAT1, which in turn decreases autophagy flux by downregulating STX17.
JOURNAL OF PERIODONTAL RESEARCH
(2023)
Review
Chemistry, Multidisciplinary
Haoran Liu, Dong Liu, Junchuan Yang, Hanfei Gao, Yuchen Wu
Summary: Organic flexible electronic devices with outstanding properties, such as solution processability, lightweight, and flexibility, have the potential to revolutionize lifestyles. The precise patterning and ordered assembly of organic semiconductors for integration in flexible electronics have attracted attention and rapidly developed. This review focuses on recent advances in the design, patterned assembly, and multifunctional applications of flexible organic field-effect transistors (FOFETs). It introduces typical organic semiconductor materials and material design methods, discusses patterned assembly strategies on flexible substrates, and highlights advanced applications of flexible electronic devices based on organic semiconductor patterns. Future challenges and possible directions for the development of the next generation of flexible electronics are also proposed.
Article
Spectroscopy
Haipei Zou, Huanling Liu, Qingfang Mu, Kai Zhang, Yuzhi Song, Lili Lin, Yuanyuan Xu, Chuan-Kui Wang, Jianzhong Fan
Summary: This study investigates the relationship between molecular structures and luminescent properties, and proposes theoretically efficient TSCT-based TADF molecules. These molecules have a large number of substitutions and adopt twist structures to achieve small energy gaps between the lowest excited states.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Endocrinology & Metabolism
Zixuan Liu, Jing Dai, Xiaodie He, Jiaxi Li, Haixia Zhang, Cheng Ji
Summary: This study aimed to investigate the incidence and influencing factors of postoperative hypoglycemia in diabetic patients during the perioperative period and construct a risk prediction model. Patients with type 2 diabetes admitted to Nanjing Drum Tower Hospital from December 2019 to January 2022 were included. A total of 440 patients were included, and the incidence of postoperative hypoglycemia was 24.78%. Preoperative C-peptide and operation duration were identified as risk factors, while BMI and preoperative fasting blood glucose were protective factors.
INTERNATIONAL JOURNAL OF ENDOCRINOLOGY
(2023)
Article
Computer Science, Artificial Intelligence
Xiang Shi, Yinpeng Liu, Jiawei Liu, Qikai Cheng, Wei Lu
Summary: Scientific papers are crucial for academic communication, but many of them lack in-depth research and present core content ambiguously, hindering the progression of science and technology. To address this challenge, the INTEGrity vERification (INTEGER) task is introduced to help researchers assess the integrity of their papers and verify the clarity of each knowledge unit. A multi-task learning model utilizing Tucker decomposition and span-level attention mechanism is proposed to accurately identify terms and their integrity. Experimental results show the effectiveness of the model.
EXPERT SYSTEMS WITH APPLICATIONS
(2024)
Article
Chemistry, Analytical
Mengmeng Guo, Na Luo, Yueling Bai, Zhenggang Xue, Qingmin Hu, Jiaqiang Xu
Summary: A porous heterostructure WO3-C/In2O3 was designed and prepared for a miniature H2 sensor, which showed higher response value, lower operating temperature, fast response-recovery speed, and low limit of detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Feng Hu, Hui Hu, Yuting Li, Xiaohui Wang, Xiaowen Shi
Summary: Arsenic contamination in water bodies is a significant health risk. This study developed a chitosan-catechol modified electrode for rapid and accurate detection of trace amounts of arsenic. The modified electrode demonstrated good detection capability and resistance to ionic interference, making it suitable for in situ detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yantao Zhang, Qian Liu, Tao Tian, Chunhua Xu, Pengli Yang, Lianju Ma, Yi Hou, Hui Zhou, Yongjun Gan
Summary: In this study, a lysosome-targeting buffering fluorogenic probe (Lyso-BFP) was designed and synthesized, demonstrating excellent photostability, pH specificity, and responsiveness to lysosomal acidification in living cells. The performance of Lyso-BFP in pH sensing was attributed to the inhibition of the photo-induced electron transfer process. Lyso-BFP allowed for wash-free imaging and long-term real-time monitoring of lysosome pH changes based on its off-on fluorescence behavior and buffer strategy.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Wei Cai, Wenbo Sun, Jiayue Wang, Xiaokui Huo, Xudong Cao, Xiangge Tian, Xiaochi Ma, Lei Feng
Summary: In this study, a near-infrared fluorescent probe HCBG was developed for imaging of alpha-GLC. HCBG exhibited excellent selectivity and sensitivity towards alpha-GLC in complex bio-samples, and showed good cell permeability for in situ real-time imaging. Through the high-throughput screening system established by HCBG, a natural alpha-GLC inhibitor was successfully isolated and identified. This study provides a novel fluorescence visualization tool for discovering and exploring the biological functions of diabetes-related gut microbiota, and a high-throughput screening approach for alpha-GLC inhibitor.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Trey W. Pittman, Xi Zhang, Chamindie Punyadeera, Charles S. Henry
Summary: Heart failure is a growing epidemic and a significant clinical and public health problem. Researchers have developed a portable and affordable diagnostic device for heart failure that can be used at the point-of-care, providing a valid alternative to current diagnostics approaches.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Anders O. Tjell, Barbara Jud, Roland Schaller-Ammann, Torsten Mayr
Summary: An optical hydrogen peroxide sensor based on catalytic degradation and the detection of produced oxygen is presented. The sensor offers higher resolution and better sensitivity at lower H2O2 concentrations. By removing O2 from the sample solution, a more sensitive O2 sensor can be used for measurement. The sensor has been successfully applied in a flow-through cell to measure H2O2 concentration in different flow rates.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Seong Jae Kim, Ji-hun Jeong, Gaabhin Ryu, Yoon Sick Eom, Sanha Kim
Summary: Surface-enhanced Raman spectroscopy (SERS) is a high-sensitivity, label-free detection method with various analytical applications. Researchers have developed a hydrophobic SERS substrate based on engineered carbon nanotube arrays (CNT-SERS) and studied the role of structural design at both micro and nanoscales. The substrate demonstrated controlled self-enrichment capability and enhanced sensitivity, with a significant increase in the SERS signal. The study also proposed a theoretical model and a concentration strategy inspired by plants for analyte deposition on microarrays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Dan Zhao, Renjun Jiang, Xiaoqiang Liu, Subbiah Alwarappan
Summary: In this study, a novel ternary composite material was constructed by assembling cerium vanadate nanorods on reduced graphene oxide-microcrystalline cellulose nanosheets, and it was used for real-time monitoring of the concentration of superoxide anions in vivo. The ternary composite showed excellent conductivity, large surface area, and abundant active sites, leading to a wider linear range, high sensitivity, low detection limit, and fast response time for superoxide anion detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Tengfei Wang, Liwen Wang, Guang Wu, Dating Tian
Summary: In this study, a covalent organic framework material TaTp-COF with porous and uniform spheres was successfully prepared via hydrothermal reaction, and it was found to significantly enhance the aggregation-induced emission (AIE) of berberine. The unique emission properties of berberine on TaTp-COF were studied and utilized for the sensitive detection of berberine.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Lin Li, Yilei Ding, Lei Xu, Shuoran Chen, Guoliang Dai, Pengju Han, Lixin Lu, Changqing Ye, Yanlin Song
Summary: In this study, a novel TTI based on a ratiometric fluorescent nanosensor is designed, which has the advantages of high accuracy and low cost. Experimental and theoretical investigations confirm its pH responsiveness and demonstrate its good sensitivity and reliability. By monitoring the total volatile basic nitrogen, this TTI can accurately predict food spoilage and can be adaptively modified for different types of food. The TTI based on this nanosensor enables visual monitoring of food quality.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Fangju Chen, Xueting Wang, Wei Chen, Chenwen Shao, Yong Qian
Summary: Lung cancer is the second most common malignant tumor worldwide. Drug resistance in lung cancer leads to treatment failure and recurrence in majority of patients. This study developed a fluorescent prodrug that can be activated in cancer cells to release drugs, and its signal can be tracked by imaging. It shows a unique autophagy-driven ferroptosis effect, indicating its potential for targeting drug-resistant cancer cells.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Weichao Li, Qiming Yuan, Zhangcheng Xia, Xiaoxue Ma, Lifang He, Ling Jin, Xiangfeng Chu, Kui Zhang
Summary: This study developed a high-performance gas sensor for formaldehyde detection by modifying ZnSnO3 with ZnO QDs and SnO2 QDs. The modified sensor showed improved sensing response and lower working temperature. The presence of ZnO QDs formed rich heterojunctions, increased surface area, and provided oxygen deficiency for formaldehyde sensing reaction, thus enhancing the sensor performance. This research provides an alternative method to enhance the sensing properties of MOS by QDs modification.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Joung-Il Moon, Eun Jung Choi, Younju Joung, Jin-Woo Oh, Sang-Woo Joo, Jaebum Choo
Summary: A novel nanoplasmonic substrate was developed for biomedical applications, which showed strong hot spots for detecting biomarkers at low concentrations. The substrate, called AuNPs@M13, was made by immobilizing 60 nm gold nanoparticles onto the surface of an M13 bacteriophage scaffold. It demonstrated higher sensitivity and lower limit of detection compared to commercially available assays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Ning Li, Ya Zhang, Ying Xu, Xiaofang Liu, Jian Chen, Mei Yang, Changjun Hou, Danqun Huo
Summary: The molecular subtype of breast cancer guides treatment and drug selection. Invasive tests can promote cancer cell metastasis, so the development of high-performance, low-cost diagnostic tools for cancer prognosis is crucial. Liquid biopsy techniques enable noninvasive, real-time, dynamic, multicomponent, quantitative, and long-term observations at the cellular, genetic, and molecular levels. A Cu-Zr metal-organic framework (MOF) nanoenzyme with monatomic Cu attachment has been synthesized and proven to have high catalytic performance. The sensor constructed using this nanoenzyme shows potential for accurate classification of breast cancer serum samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Jeongmin Kim, Hyemin Kim, Seunghyun Park, Hyeonaug Hong, Yong Jae Kim, Jiyong Lee, Jaeho Kim, Seung-Woo Cho, Wonhyoung Ryu
Summary: This study presents a method to fabricate independently functioning microneedle (MN) electrodes with narrow intervals for high precision electrochemical sensing. The optimized mixture of photocurable polymer and single-wall carbon nanotubes was used to mold single composite MNs, which were then attached to pre-patterned electrodes. Plasma etching and electropolymerization were performed to enhance the electrochemical activity, and Prussian blue and glucose oxidase were electrodeposited on the MNs for glucose detection. The MN electrodes showed good sensitivity and linearity, and the feasibility of glucose detection was demonstrated in an in vivo mouse study.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
