Exponential amplification reaction-based fluorescent sensor for the sensitive detection of tumor biomarker flap endonuclease 1

Fluorometric detection of cancer marker FEN1 based on double-flapped dumbbell DNA nanoprobe functionalized with silver nanoclusters

(2021) Bingzhi Li et al.   ANALYTICA CHIMICA ACTA

Signal-Amplified Detection of the Tumor Biomarker FEN1 Based on Cleavage-Induced Ligation of a Dumbbell DNA Probe and Rolling Circle Amplification

(2021) Bingzhi Li et al.   ANALYTICAL CHEMISTRY

Fluorescent Assay of FEN1 Activity with Nicking Enzyme-Assisted Signal Amplification Based on ZIF-8 for Imaging in Living Cells

(2021) Yunfei Tang et al.   ANALYTICAL CHEMISTRY

An exonuclease protection and CRISPR/Cas12a integrated biosensor for the turn-on detection of transcription factors in cancer cells

(2021) Bingzhi Li et al.   ANALYTICA CHIMICA ACTA

The single-cell pathology landscape of breast cancer

(2020) Hartland W. Jackson et al.   NATURE

Sensing Biomarkers with Plasmonics

(2020) Nicole Cathcart et al.   ANALYTICAL CHEMISTRY

A signal transduction approach for multiplexed detection of transcription factors by integrating DNA nanotechnology, multi-channeled isothermal amplification, and chromatography

(2020) Yue Chen et al.   JOURNAL OF CHROMATOGRAPHY A

FEN1 endonuclease as a therapeutic target for human cancers with defects in homologous recombination

(2020) Elaine Guo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A CRISPR-derived biosensor for the sensitive detection of transcription factors based on the target-induced inhibition of Cas12a activation

(2020) Bingzhi Li et al.   BIOSENSORS & BIOELECTRONICS

Biological and clinical significance of flap endonuclease‑1 in triple‑negative breast cancer: Support of metastasis and a poor prognosis

(2020) Lu Xu et al.   ONCOLOGY REPORTS

Terminal deoxynucleotidyl transferase combined CRISPR-Cas12a amplification strategy for ultrasensitive detection of uracil-DNA glycosylase with zero background

(2020) Yi-Chen Du et al.   BIOSENSORS & BIOELECTRONICS

Sensitive homogeneous fluorescent detection of DNA glycosylase by target-triggering ligation-dependent tricyclic cascade amplification

(2020) Huige Zhang et al.   TALANTA

Letrozole improves the sensitivity of breast cancer cells overexpressing aromatase to cisplatin via down-regulation of FEN1

(2019) Y. Wang et al.   Clinical & Translational Oncology

Sulforaphane inhibits epithelial-mesenchymal transition by activating extracellular signal-regulated kinase 5 in lung Cancer cells

(2019) Yue Chen et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Overexpression of Flap Endonuclease 1 Correlates with Enhanced Proliferation and Poor Prognosis of Non–Small-Cell Lung Cancer

(2018) Keqiang Zhang et al.   AMERICAN JOURNAL OF PATHOLOGY

Exponential isothermal amplification of nucleic acids and amplified assays for proteins, cells, and enzyme activities

(2018) Michael S Reid et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A novel exonuclease-assisted isothermal nucleic acid amplification with ultrahigh specificity mediated by full-length Bst DNA polymerase

(2018) Xin Ye et al.   CHEMICAL COMMUNICATIONS

Exonuclease III-assisted multiple cycle amplification for sensitive detection of DNA with zero background signal

(2018) Wen-jing Liu et al.   ANALYST

Reduction of Background Generated from Template-Template Hybridizations in the Exponential Amplification Reaction

(2018) Michael S. Reid et al.   ANALYTICAL CHEMISTRY

Versatile Types of DNA-Based Nanobiosensors for Specific Detection of Cancer Biomarker FEN1 in Living Cells and Cell-Free Systems

(2018) Hao Zhang et al.   NANO LETTERS

Investigation of human flap structure-specific endonuclease 1 (FEN1) activity on primer-template models and exploration of a substrate-based FEN1 inhibitor

(2016) Sai Ba et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Label-free, homogeneous, and ultrasensitive detection of pathogenic bacteria based on target-triggered isothermally exponential amplification

(2016) Tingting Qiu et al.   RSC Advances

Ultrasensitive Detection of Transcription Factors Using Transcription-Mediated Isothermally Exponential Amplification-Induced Chemiluminescence

(2014) Fei Ma et al.   ANALYTICAL CHEMISTRY

Exponential amplification of DNA with very low background using graphene oxide and single-stranded binding protein to suppress non-specific amplification

(2014) Jianping Wang et al.   MICROCHIMICA ACTA

Real-time fluorescence detection of Hg2+ ions with high sensitivity by exponentially isothermal oligonucleotide amplification

(2014) Hongxia Jia et al.   RSC Advances

Real-Time Detection of Transcription Factors Using Target-Converted Helicase-Dependent Amplification Assay with Zero-Background Signal

(2013) Anping Cao et al.   ANALYTICAL CHEMISTRY

Functional FEN1 genetic variants and haplotypes are associated with glioma risk

(2012) Yi-Dong Chen et al.   JOURNAL OF NEURO-ONCOLOGY

Sequence dependence of isothermal DNA amplification via EXPAR

(2012) Jifeng Qian et al.   NUCLEIC ACIDS RESEARCH

Identification of Proteins Sensitive to Thermal Stress in Human Neuroblastoma and Glioma Cell Lines

(2012) Guilian Xu et al.   PLoS One

FEN Nucleases: Bind, Bend, Fray, Cut

(2011) R. Scott Williams et al.   CELL

Human Flap Endonuclease Structures, DNA Double-Base Flipping, and a Unified Understanding of the FEN1 Superfamily

(2011) Susan E. Tsutakawa et al.   CELL

Ultrasensitive Detection of microRNAs by Exponential Isothermal Amplification

(2010) Hongxia Jia et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION