The role of AMPAR lateral diffusion in memory

Advanced imaging and labelling methods to decipher brain cell organization and function

(2021) Daniel Choquet et al.   NATURE REVIEWS NEUROSCIENCE

Hippocampal AMPA receptor assemblies and mechanism of allosteric inhibition

(2021) Jie Yu et al.   NATURE

CaMKII activation persistently segregates postsynaptic proteins via liquid phase separation

(2021) Tomohisa Hosokawa et al.   NATURE NEUROSCIENCE

Phase separation at the synapse

(2020) Xudong Chen et al.   NATURE NEUROSCIENCE

Syntaxin-3 is dispensable for basal neurotransmission and synaptic plasticity in postsynaptic hippocampal CA1 neurons

(2020) Shan Shi et al.   Scientific Reports

Optogenetic control of excitatory post-synaptic differentiation through neuroligin-1 tyrosine phosphorylation

(2020) Mathieu Letellier et al.   eLife

AMPA receptor nanoscale dynamic organization and synaptic plasticities

(2020) Daniel Choquet et al.   CURRENT OPINION IN NEUROBIOLOGY

GRIP1 regulates synaptic plasticity and learning and memory

(2020) Han L. Tan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

AMPAR-Dependent Synaptic Plasticity Initiates Cortical Remapping and Adaptive Behaviors during Sensory Experience

(2020) Tiago Campelo et al.   Cell Reports

Long-term potentiation is independent of the C-tail of the GluA1 AMPA receptor subunit

(2020) Javier Díaz-Alonso et al.   eLife

Neuroligin-1 Signaling Controls LTP and NMDA Receptors by Distinct Molecular Pathways

(2019) Xiaoting Wu et al.   NEURON

SNAP-25 isoforms differentially regulate synaptic transmission and long-term synaptic plasticity at central synapses

(2019) Muhammad Irfan et al.   Scientific Reports

The next generation of approaches to investigate the link between synaptic plasticity and learning

(2019) Yann Humeau et al.   NATURE NEUROSCIENCE

Phase Separation-Mediated TARP/MAGUK Complex Condensation and AMPA Receptor Synaptic Transmission

(2019) Menglong Zeng et al.   NEURON

Cortical Synaptic AMPA Receptor Plasticity during Motor Learning

(2019) Richard H. Roth et al.   NEURON

Synaptic nanomodules underlie the organization and plasticity of spine synapses

(2018) Martin Hruska et al.   NATURE NEUROSCIENCE

Deletion ofLRRTM1 and LRRTM2in adult mice impairs basal AMPA receptor transmission and LTP in hippocampal CA1 pyramidal neurons

(2018) Mehdi Bhouri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

LTP requires postsynaptic PDZ-domain interactions with glutamate receptor/auxiliary protein complexes

(2018) Nengyin Sheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synaptic Capture of Laterally Diffusing AMPA Receptors – An Idea That Stuck

(2018) Margaret H. Hastings et al.   TRENDS IN NEUROSCIENCES

Wnt Signaling Mediates LTP-Dependent Spine Plasticity and AMPAR Localization through Frizzled-7 Receptors

(2018) Faye McLeod et al.   Cell Reports

SynDIG4/Prrt1 Is Required for Excitatory Synapse Development and Plasticity Underlying Cognitive Function

(2018) Lucas Matt et al.   Cell Reports

Crucial Role of Postsynaptic Syntaxin 4 in Mediating Basal Neurotransmission and Synaptic Plasticity in Hippocampal CA1 Neurons

(2018) Na-Ryum Bin et al.   Cell Reports

CaMKII Metaplasticity Drives Aβ Oligomer-Mediated Synaptotoxicity

(2018) Patricio Opazo et al.   Cell Reports

Reconstituted Postsynaptic Density as a Molecular Platform for Understanding Synapse Formation and Plasticity

(2018) Menglong Zeng et al.   CELL

A unique intracellular tyrosine in neuroligin-1 regulates AMPA receptor recruitment during synapse differentiation and potentiation

(2018) Mathieu Letellier et al.   Nature Communications

Noelin1 Affects Lateral Mobility of Synaptic AMPA Receptors

(2018) Nikhil J. Pandya et al.   Cell Reports

Linking Nanoscale Dynamics of AMPA Receptor Organization to Plasticity of Excitatory Synapses and Learning

(2018) Daniel Choquet   JOURNAL OF NEUROSCIENCE

Mechanisms and Role of Dendritic Membrane Trafficking for Long-Term Potentiation

(2018) Brian G. Hiester et al.   Frontiers in Cellular Neuroscience

Modulation of AMPA receptor surface diffusion restores hippocampal plasticity and memory in Huntington’s disease models

(2018) Hongyu Zhang et al.   Nature Communications

Postsynaptic synaptotagmins mediate AMPA receptor exocytosis during LTP

(2017) Dick Wu et al.   NATURE

Hippocampal LTP and contextual learning require surface diffusion of AMPA receptors

(2017) A. C. Penn et al.   NATURE

The C-terminal tails of endogenous GluA1 and GluA2 differentially contribute to hippocampal synaptic plasticity and learning

(2017) Zikai Zhou et al.   NATURE NEUROSCIENCE

CaMKII Autophosphorylation Is Necessary for Optimal Integration of Ca 2+ Signals during LTP Induction, but Not Maintenance

(2017) Jui-Yun Chang et al.   NEURON

Kinetics of Endogenous CaMKII Required for Synaptic Plasticity Revealed by Optogenetic Kinase Inhibitor

(2017) Hideji Murakoshi et al.   NEURON

A Brief History of Long-Term Potentiation

(2017) Roger A. Nicoll   NEURON

Conditional ablation of neuroligin-1 in CA1 pyramidal neurons blocks LTP by a cell-autonomous NMDA receptor-independent mechanism

(2016) M Jiang et al.   MOLECULAR PSYCHIATRY

Autocrine BDNF–TrkB signalling within a single dendritic spine

(2016) Stephen C. Harward et al.   NATURE

A trans-synaptic nanocolumn aligns neurotransmitter release to receptors

(2016) Ai-Hui Tang et al.   NATURE

Optical inactivation of synaptic AMPA receptors erases fear memory

(2016) Kiwamu Takemoto et al.   NATURE BIOTECHNOLOGY

CaMKII Phosphorylation of TARPγ-8 Is a Mediator of LTP and Learning and Memory

(2016) Joongkyu Park et al.   NEURON

Shisa6 traps AMPA receptors at postsynaptic sites and prevents their desensitization during synaptic activity

(2016) Remco V. Klaassen et al.   Nature Communications

PSD95 nanoclusters are postsynaptic building blocks in hippocampus circuits

(2016) Matthew J. Broadhead et al.   Scientific Reports

Synaptic adhesion molecule IgSF11 regulates synaptic transmission and plasticity

(2015) Seil Jang et al.   NATURE NEUROSCIENCE

Lengthening of the Stargazin Cytoplasmic Tail Increases Synaptic Transmission by Promoting Interaction to Deeper Domains of PSD-95

(2015) Anne-Sophie Hafner et al.   NEURON

Hippocampal Wnt Signaling

(2015) Ashley M. Fortress et al.   NEUROSCIENTIST

Hippocampal Wnt3a is Necessary and Sufficient for Contextual Fear Memory Acquisition and Consolidation

(2014) Ning Xu et al.   CEREBRAL CORTEX

Engineering a memory with LTD and LTP

(2014) Sadegh Nabavi et al.   NATURE

Regional Diversity and Developmental Dynamics of the AMPA-Receptor Proteome in the Mammalian Brain

(2014) Jochen Schwenk et al.   NEURON

Super-Resolution Imaging Reveals That AMPA Receptors Inside Synapses Are Dynamically Organized in Nanodomains Regulated by PSD95

(2013) D. Nair et al.   JOURNAL OF NEUROSCIENCE

Cornichon Proteins Determine the Subunit Composition of Synaptic AMPA Receptors

(2013) Bruce E. Herring et al.   NEURON

LTP Requires a Unique Postsynaptic SNARE Fusion Machinery

(2013) Sandra Jurado et al.   NEURON

Nanoscale Scaffolding Domains within the Postsynaptic Density Concentrate Synaptic AMPA Receptors

(2013) Harold D. MacGillavry et al.   NEURON

AMPARs and Synaptic Plasticity: The Last 25 Years

(2013) Richard L. Huganir et al.   NEURON

BDNF and memory processing

(2013) Pedro Bekinschtein et al.   NEUROPHARMACOLOGY

Neurexin-1β Binding to Neuroligin-1 Triggers the Preferential Recruitment of PSD-95 versus Gephyrin through Tyrosine Phosphorylation of Neuroligin-1

(2013) Grégory Giannone et al.   Cell Reports

Regulation of AMPA receptor trafficking and synaptic plasticity

(2012) Victor Anggono et al.   CURRENT OPINION IN NEUROBIOLOGY

LTP requires a reserve pool of glutamate receptors independent of subunit type

(2012) Adam J. Granger et al.   NATURE

Neurotrophin regulation of neural circuit development and function

(2012) Hyungju Park et al.   NATURE REVIEWS NEUROSCIENCE

Postsynaptic Complexin Controls AMPA Receptor Exocytosis during LTP

(2012) Mohiuddin Ahmad et al.   NEURON

Regulation of AMPA receptor surface diffusion by PSD-95 slots

(2011) Patricio Opazo et al.   CURRENT OPINION IN NEUROBIOLOGY

Neurexin-Neuroligin Adhesions Capture Surface-Diffusing AMPA Receptors through PSD-95 Scaffolds

(2011) M. Mondin et al.   JOURNAL OF NEUROSCIENCE

PDZ binding of TARPγ-8 controls synaptic transmission but not synaptic plasticity

(2011) Akio Sumioka et al.   NATURE NEUROSCIENCE

Variability, compensation, and modulation in neurons and circuits

(2011) E. Marder   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Syntaxin-4 Defines a Domain for Activity-Dependent Exocytosis in Dendritic Spines

(2010) Matthew J. Kennedy et al.   CELL

Neuroligin-1 Deletion Results in Impaired Spatial Memory and Increased Repetitive Behavior

(2010) J. Blundell et al.   JOURNAL OF NEUROSCIENCE

A three-step model for the synaptic recruitment of AMPA receptors

(2010) Patricio Opazo et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

CaMKII Triggers the Diffusional Trapping of Surface AMPARs through Phosphorylation of Stargazin

(2010) Patricio Opazo et al.   NEURON

TARP Phosphorylation Regulates Synaptic AMPA Receptors through Lipid Bilayers

(2010) Akio Sumioka et al.   NEURON

AMPA receptors are exocytosed in stimulated spines and adjacent dendrites in a Ras-ERK-dependent manner during long-term potentiation

(2010) M. A. Patterson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation of CaMKII in single dendritic spines during long-term potentiation

(2009) Seok-Jin R. Lee et al.   NATURE

The Pre/Post LTP Debate

(2009) John E. Lisman   NEURON

LRRTM2 Interacts with Neurexin1 and Regulates Excitatory Synapse Formation

(2009) Joris de Wit et al.   NEURON

Endocytic Trafficking and Recycling Maintain a Pool of Mobile Surface AMPA Receptors Required for Synaptic Potentiation

(2009) Enrica Maria Petrini et al.   NEURON

Synaptic AMPA Receptor Plasticity and Behavior

(2009) Helmut W. Kessels et al.   NEURON

AMPA Receptor Incorporation into Synapses during LTP: The Role of Lateral Movement and Exocytosis

(2009) Hiroshi Makino et al.   NEURON

Myosin Vb Mobilizes Recycling Endosomes and AMPA Receptors for Postsynaptic Plasticity

(2008) Zhiping Wang et al.   CELL

Silent synapses and the emergence of a postsynaptic mechanism for LTP

(2008) Geoffrey A. Kerchner et al.   NATURE REVIEWS NEUROSCIENCE