Paving the way for application of next generation risk assessment to safety decision-making for cosmetic ingredients
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Paving the way for application of next generation risk assessment to safety decision-making for cosmetic ingredients
Authors
Keywords
Non-animal approaches, In vitro, In silico, Next generation risk assessment
Journal
REGULATORY TOXICOLOGY AND PHARMACOLOGY
Volume 125, Issue -, Pages 105026
Publisher
Elsevier BV
Online
2021-08-11
DOI
10.1016/j.yrtph.2021.105026
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The way forward for assessing the human health safety of cosmetics in the eu workshop proceedings
- (2020) Vera Rogiers et al. TOXICOLOGY
- A next generation risk assessment case study for coumarin in cosmetic products
- (2020) M T Baltazar et al. TOXICOLOGICAL SCIENCES
- Identifying and Characterizing Stress Pathways of Concern for Consumer Safety in Next-Generation Risk Assessment
- (2020) Sarah Hatherell et al. TOXICOLOGICAL SCIENCES
- Application of structural and functional pharmacokinetic analogs for physiologically based pharmacokinetic model development and evaluation
- (2020) Corie A. Ellison et al. REGULATORY TOXICOLOGY AND PHARMACOLOGY
- An interim internal Threshold of Toxicologic Concern (iTTC) for chemicals in consumer products, with support from an automated assessment of ToxCast™ dose response data
- (2020) Karen L. Blackburn et al. REGULATORY TOXICOLOGY AND PHARMACOLOGY
- Evaluation of 5-day In Vivo Rat Liver and Kidney With High-throughput Transcriptomics for Estimating Benchmark Doses of Apical Outcomes
- (2020) William M Gwinn et al. TOXICOLOGICAL SCIENCES
- The next generation blueprint of computational toxicology at the U.S. Environmental Protection Agency
- (2019) Russell S Thomas et al. TOXICOLOGICAL SCIENCES
- Challenges in working towards an internal threshold of toxicological concern (iTTC) for use in the safety assessment of cosmetics: Discussions from the Cosmetics Europe iTTC Working Group workshop
- (2019) Corie A. Ellison et al. REGULATORY TOXICOLOGY AND PHARMACOLOGY
- Use of Connectivity Mapping to Support Read Across: A Deeper Dive Using Data from 186 Chemicals, 19 Cell lines and 2 Case Studies
- (2019) K. Nadira De Abrew et al. TOXICOLOGY
- Utility of In Vitro Bioactivity as a Lower Bound Estimate of In Vivo Adverse Effect Levels and in Risk-Based Prioritization
- (2019) Katie Paul Friedman et al. TOXICOLOGICAL SCIENCES
- Current nonclinical in vivo safety pharmacology testing enables safe entry to first-in-human clinical trials: The IQ consortium nonclinical to clinical translational database
- (2019) David Ackley et al. JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS
- Application of physiologically based kinetic (PBK) modelling in the next generation risk assessment of dermally applied consumer products
- (2019) Thomas E. Moxon et al. TOXICOLOGY IN VITRO
- The application of transcriptional benchmark dose modeling for deriving thresholds of effects associated with solar-simulated ultraviolet radiation exposure
- (2018) Sami S. Qutob et al. ENVIRONMENTAL AND MOLECULAR MUTAGENESIS
- Evaluating In Vitro-In Vivo Extrapolation of Toxicokinetics
- (2018) John F Wambaugh et al. TOXICOLOGICAL SCIENCES
- A strategy for systemic toxicity assessment based on non-animal approaches: The Cosmetics Europe Long Range Science Strategy programme
- (2018) Bertrand Desprez et al. TOXICOLOGY IN VITRO
- Hepatic transcriptional dose-response analysis of male and female Fischer rats exposed to hexabromocyclododecane
- (2018) Reza Farmahin et al. FOOD AND CHEMICAL TOXICOLOGY
- Current nonclinical testing paradigm enables safe entry to First-In-Human clinical trials: The IQ consortium nonclinical to clinical translational database
- (2017) Thomas M. Monticello et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Potential functional and pathological side effects related to off-target pharmacological activity
- (2017) James J. Lynch et al. JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS
- Recommended approaches in the application of toxicogenomics to derive points of departure for chemical risk assessment
- (2016) Reza Farmahin et al. ARCHIVES OF TOXICOLOGY
- Secondary pharmacology: screening and interpretation of off-target activities – focus on translation
- (2016) Steven Whitebread et al. DRUG DISCOVERY TODAY
- Grouping 34 Chemicals Based on Mode of Action Using Connectivity Mapping
- (2016) K. Nadira De Abrew et al. TOXICOLOGICAL SCIENCES
- Comparative transcriptomic analyses to scrutinize the assumption that genotoxic PAHs exert effects via a common mode of action
- (2015) S. Labib et al. ARCHIVES OF TOXICOLOGY
- Screening Chemicals for Estrogen Receptor Bioactivity Using a Computational Model
- (2015) Patience Browne et al. ENVIRONMENTAL SCIENCE & TECHNOLOGY
- Nano-risk Science: application of toxicogenomics in an adverse outcome pathway framework for risk assessment of multi-walled carbon nanotubes
- (2015) Sarah Labib et al. Particle and Fibre Toxicology
- Development of a physiologically-based pharmacokinetic model of 2-phenoxyethanol and its metabolite phenoxyacetic acid in rats and humans to address toxicokinetic uncertainty in risk assessment
- (2015) John A. Troutman et al. REGULATORY TOXICOLOGY AND PHARMACOLOGY
- Defining Molecular Initiating Events in the Adverse Outcome Pathway Framework for Risk Assessment
- (2014) Timothy E. H. Allen et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Can case study approaches speed implementation of the NRC report: “Toxicity Testing in the 21st Century: A Vision and a Strategy?”
- (2014) Melvin Andersen ALTEX-Alternatives to Animal Experimentation
- Reverse causal reasoning: applying qualitative causal knowledge to the interpretation of high-throughput data
- (2013) Natalie L Catlett et al. BMC BIOINFORMATICS
- Framework for Identifying Chemicals with Structural Features Associated with the Potential to Act as Developmental or Reproductive Toxicants
- (2013) Shengde Wu et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Reducing safety-related drug attrition: the use of in vitro pharmacological profiling
- (2012) Joanne Bowes et al. NATURE REVIEWS DRUG DISCOVERY
- Concentration- and Time-dependent Genomic Changes in the Mouse Urinary Bladder Following Exposure to Arsenate in Drinking Water for up to 12 Weeks
- (2011) H. J. Clewell et al. TOXICOLOGICAL SCIENCES
- Application of Transcriptional Benchmark Dose Values in Quantitative Cancer and Noncancer Risk Assessment
- (2010) Russell S. Thomas et al. TOXICOLOGICAL SCIENCES
- A tiered approach to the use of alternatives to animal testing for the safety assessment of cosmetics: Skin irritation
- (2009) Martin Macfarlane et al. REGULATORY TOXICOLOGY AND PHARMACOLOGY
- Cellular Stress Response Pathway System as a Sentinel Ensemble in Toxicological Screening
- (2009) Steven O. Simmons et al. TOXICOLOGICAL SCIENCES
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More