LCDR regulates the integrity of lysosomal membrane by hnRNP K–stabilized LAPTM5 transcript and promotes cell survival

Lysosome biogenesis: Regulation and functions

(2021) Chonglin Yang et al.   JOURNAL OF CELL BIOLOGY

RNA-binding motifs of hnRNP K are critical for induction of antibody diversification by activation-induced cytidine deaminase

(2020) Ziwei Yin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Histone Deacetylase Inhibition in Non-small Cell Lung Cancer: Hype or Hope?

(2020) Hirva Mamdani et al.   Frontiers in Cell and Developmental Biology

DMDRMR-mediated regulation of m6A-modified CDK4 by m6A reader IGF2BP3 drives ccRCC progression

(2020) Shan Gao et al.   CANCER RESEARCH

The molecular machinery of regulated cell death

(2019) Daolin Tang et al.   CELL RESEARCH

lncRNA PSTAR Promotes p53 Signaling by Inhibiting hnRNP K deSUMOylation and Suppresses Hepatocellular Carcinoma

(2019) Geng Qin et al.   HEPATOLOGY

Tucidinostat plus exemestane for postmenopausal patients with advanced, hormone receptor-positive breast cancer (ACE): a randomised, double-blind, placebo-controlled, phase 3 trial

(2019) Zefei Jiang et al.   LANCET ONCOLOGY

Nuclear TARBP2 Drives Oncogenic Dysregulation of RNA Splicing and Decay

(2019) Lisa Fish et al.   MOLECULAR CELL

The transcription factor CBFB suppresses breast cancer through orchestrating translation and transcription

(2019) Navdeep Malik et al.   Nature Communications

The emerging roles of hnRNPK

(2019) Ziyi Wang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The long non-coding RNA PCSEAT exhibits an oncogenic property in prostate cancer and functions as a competing endogenous RNA that associates with EZH2

(2018) Xiaohui Yang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Long Noncoding RNA pancEts-1 Promotes Neuroblastoma Progression through hnRNPK-Mediated β-Catenin Stabilization

(2018) Dan Li et al.   CANCER RESEARCH

Interplay between long non-coding RNAs and epigenetic machinery: emerging targets in cancer?

(2018) David J. Hanly et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Lysosomal membrane permeabilization and cell death

(2018) Fengjuan Wang et al.   TRAFFIC

Regulation of Mcl-1 alternative splicing by hnRNP F, H1 and K in breast cancer cells

(2018) Alison Tyson-Capper et al.   RNA Biology

Ectopic overexpression of LAPTM5 results in lysosomal targeting and induces Mcl-1 down-regulation, Bak activation, and mitochondria-dependent apoptosis in human HeLa cells

(2017) Do Youn Jun et al.   PLoS One

Ultra-pH-Responsive and Tumor-Penetrating Nanoplatform for Targeted siRNA Delivery with Robust Anti-Cancer Efficacy

(2016) Xiaoding Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Long Noncoding RNAs in Cancer Pathways

(2016) Adam M. Schmitt et al.   CANCER CELL

Long non-coding RNA CASC11 interacts with hnRNP-K and activates the WNT/β-catenin pathway to promote growth and metastasis in colorectal cancer

(2016) Zheying Zhang et al.   CANCER LETTERS

Histone Modifications and Cancer

(2016) James E. Audia et al.   Cold Spring Harbor Perspectives in Biology

Down-regulation of LAPTM5 in human cancer cells

(2016) Michelle Nuylan et al.   Oncotarget

hnRNP K Is a Haploinsufficient Tumor Suppressor that Regulates Proliferation and Differentiation Programs in Hematologic Malignancies

(2015) Miguel Gallardo et al.   CANCER CELL

The emerging role of lncRNAs in cancer

(2015) Maite Huarte   NATURE MEDICINE

Expression of Class I Histone Deacetylases Indicates Poor Prognosis in Endometrioid Subtypes of Ovarian and Endometrial Carcinomas

(2015) Wilko Weichert et al.   NEOPLASIA

Non-viral vectors for gene-based therapy

(2014) Hao Yin et al.   NATURE REVIEWS GENETICS

hnRNP K suppresses apoptosis independent of p53 status by maintaining high levels of endogenous caspase inhibitors

(2013) Ziwei Xiao et al.   CARCINOGENESIS

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

The antiapoptotic protein, FLIP, is regulated by heterogeneous nuclear ribonucleoprotein K and correlates with poor overall survival of nasopharyngeal carcinoma patients

(2010) L-C Chen et al.   CELL DEATH AND DIFFERENTIATION

Heterogeneous Nuclear Ribonucleoprotein K Represses the Production of Pro-apoptotic Bcl-xSSplice Isoform

(2009) Timothée Revil et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lysosomal-Associated Protein Multispanning Transmembrane 5 Gene (LAPTM5) Is Associated with Spontaneous Regression of Neuroblastomas

(2009) Jun Inoue et al.   PLoS One

Lysosomal involvement in cell death and cancer

(2008) Thomas Kirkegaard et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Histone Deacetylase 8 in Neuroblastoma Tumorigenesis

(2008) I. Oehme et al.   CLINICAL CANCER RESEARCH

Association of patterns of class I histone deacetylase expression with patient prognosis in gastric cancer: a retrospective analysis

(2008) Wilko Weichert et al.   LANCET ONCOLOGY