Multispecific targeting of glioblastoma with tumor microenvironment-responsive multifunctional engineered NK cells
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Title
Multispecific targeting of glioblastoma with tumor microenvironment-responsive multifunctional engineered NK cells
Authors
Keywords
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Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 118, Issue 45, Pages e2107507118
Publisher
Proceedings of the National Academy of Sciences
Online
2021-11-06
DOI
10.1073/pnas.2107507118
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Note: Only part of the references are listed.- Understanding the glioblastoma immune microenvironment as basis for the development of new immunotherapeutic strategies
- (2020) Ana Rita Pombo Antunes et al. eLife
- Characterizing the Dysfunctional NK Cell: Assessing the Clinical Relevance of Exhaustion, Anergy, and Senescence
- (2020) Sean J. Judge et al. Frontiers in Cellular and Infection Microbiology
- Tackling the Many Facets of Glioblastoma Heterogeneity
- (2020) Itay Tirosh et al. Cell Stem Cell
- Functional and metabolic targeting of natural killer cells to solid tumors
- (2020) Jiao Wang et al. CELLULAR ONCOLOGY
- Management of glioblastoma: State of the art and future directions
- (2020) Aaron C. Tan et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Molecular Heterogeneity and Immunosuppressive Microenvironment in Glioblastoma
- (2020) Syreeta DeCordova et al. Frontiers in Immunology
- Prognostic Significance of Tumor-Infiltrating Natural Killer Cells in Solid Tumors: A Systematic Review and Meta-Analysis
- (2020) Shuo Zhang et al. Frontiers in Immunology
- Rosuvastatin Enhances VSV-G Lentiviral Transduction of NK Cells via Upregulation of the Low-Density Lipoprotein Receptor
- (2020) Ying Gong et al. Molecular Therapy-Methods & Clinical Development
- Disialoganglioside GD2 Expression in Solid Tumors and Role as a Target for Cancer Therapy
- (2020) Bassel Nazha et al. Frontiers in Oncology
- Chloroquine against malaria, cancers and viral diseases
- (2020) Wenmin Zhou et al. DRUG DISCOVERY TODAY
- Genetically Engineered T-Cells for Malignant Glioma: Overcoming the Barriers to Effective Immunotherapy
- (2019) Pavlina Chuntova et al. Frontiers in Immunology
- Clinical observation of lymphopenia in patients with newly diagnosed glioblastoma
- (2019) Woo Jin Kim et al. JOURNAL OF NEURO-ONCOLOGY
- CAR T cells for brain tumors: Lessons learned and road ahead
- (2019) David Akhavan et al. IMMUNOLOGICAL REVIEWS
- Proneural-Mesenchymal Transition: Phenotypic Plasticity to Acquire Multitherapy Resistance in Glioblastoma
- (2019) Monica Fedele et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- NT5E/CD73 as Correlative Factor of Patient Survival and Natural Killer Cell Infiltration in Glioblastoma
- (2019) Jiao Wang et al. Journal of Clinical Medicine
- Patient-Derived Glioma Models: From Patients to Dish to Animals
- (2019) Cintia Carla da Hora et al. Cells
- Glioblastoma: Targeting the autophagy in tumorigenesis
- (2019) Kang Yang et al. BRAIN RESEARCH BULLETIN
- Targeting Autophagy for Cancer Treatment and Tumor Chemosensitization
- (2019) Marta Pérez-Hernández et al. Cancers
- Expression profiling of single cells and patient cohorts identifies multiple immunosuppressive pathways and an altered NK cell phenotype in glioblastoma
- (2019) H. J. Close et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- NK Cells Stimulate Recruitment of cDC1 into the Tumor Microenvironment Promoting Cancer Immune Control
- (2018) Jan P. Böttcher et al. CELL
- T-Cell Exhaustion Signatures Vary with Tumor Type and Are Severe in Glioblastoma
- (2018) Karolina Woroniecka et al. CLINICAL CANCER RESEARCH
- NKG2D ligands in glioma stem-like cells: expression in situ and in vitro
- (2018) Charlotte Flüh et al. HISTOCHEMISTRY AND CELL BIOLOGY
- Temozolomide, sirolimus and chloroquine is a new therapeutic combination that synergizes to disrupt lysosomal function and cholesterol homeostasis in GBM cells
- (2018) Sanford Hsu et al. Oncotarget
- Adenosinergic signaling as a target for natural killer cell immunotherapy
- (2018) Jiao Wang et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Re-purposing Chloroquine for Glioblastoma: Potential Merits and Confounding Variables
- (2018) Patrick Weyerhäuser et al. Frontiers in Oncology
- Adenosinergic Signaling Alters Natural Killer Cell Functional Responses
- (2018) Andrea M. Chambers et al. Frontiers in Immunology
- Purinergic targeting enhances immunotherapy of CD73+ solid tumors with piggyBac-engineered chimeric antigen receptor natural killer cells
- (2018) Jiao Wang et al. Journal for ImmunoTherapy of Cancer
- Immunotherapy for Brain Tumors
- (2017) John H. Sampson et al. JOURNAL OF CLINICAL ONCOLOGY
- Development of a direct contact astrocyte-human cerebral microvessel endothelial cells blood-brain barrier coculture model
- (2017) Chris Kulczar et al. JOURNAL OF PHARMACY AND PHARMACOLOGY
- Rindopepimut with temozolomide for patients with newly diagnosed, EGFRvIII-expressing glioblastoma (ACT IV): a randomised, double-blind, international phase 3 trial
- (2017) Michael Weller et al. LANCET ONCOLOGY
- OS10.3 Randomized Phase 3 Study Evaluating the Efficacy and Safety of Nivolumab vs Bevacizumab in Patients With Recurrent Glioblastoma: CheckMate 143
- (2017) D. A. Reardon et al. NEURO-ONCOLOGY
- Targeting autophagy inhibits melanoma growth by enhancing NK cells infiltration in a CCL5-dependent manner
- (2017) Takouhie Mgrditchian et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A single dose of peripherally infused EGFRvIII-directed CAR T cells mediates antigen loss and induces adaptive resistance in patients with recurrent glioblastoma
- (2017) Donald M. O’Rourke et al. Science Translational Medicine
- HER2-Specific Chimeric Antigen Receptor–Modified Virus-Specific T Cells for Progressive Glioblastoma
- (2017) Nabil Ahmed et al. JAMA Oncology
- CCL2 Produced by the Glioma Microenvironment Is Essential for the Recruitment of Regulatory T Cells and Myeloid-Derived Suppressor Cells
- (2016) Alan L. Chang et al. CANCER RESEARCH
- Targeting autophagy to sensitive glioma to temozolomide treatment
- (2016) Yuanliang Yan et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Regression of Glioblastoma after Chimeric Antigen Receptor T-Cell Therapy
- (2016) Christine E. Brown et al. NEW ENGLAND JOURNAL OF MEDICINE
- Glycolipid GD3 and GD3 synthase are key drivers for glioblastoma stem cells and tumorigenicity
- (2016) Shih-Chi Yeh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Bioactivity and Safety of IL13R 2-Redirected Chimeric Antigen Receptor CD8+ T Cells in Patients with Recurrent Glioblastoma
- (2015) C. E. Brown et al. CLINICAL CANCER RESEARCH
- Engineering NK Cells Modified With an EGFRvIII-specific Chimeric Antigen Receptor to Overexpress CXCR4 Improves Immunotherapy of CXCL12/SDF-1α-secreting Glioblastoma
- (2015) Nadja Müller et al. JOURNAL OF IMMUNOTHERAPY
- ErbB2/HER2-Specific NK Cells for Targeted Therapy of Glioblastoma
- (2015) Congcong Zhang et al. JNCI-Journal of the National Cancer Institute
- ErbB2/HER2-Specific NK Cells for Targeted Therapy of Glioblastoma
- (2015) Congcong Zhang et al. JNCI-Journal of the National Cancer Institute
- Dual targeting of glioblastoma with chimeric antigen receptor-engineered natural killer cells overcomes heterogeneity of target antigen expression and enhances antitumor activity and survival
- (2015) Sabrina Genßler et al. OncoImmunology
- CAR-Engineered NK Cells Targeting Wild-Type EGFR and EGFRvIII Enhance Killing of Glioblastoma and Patient-Derived Glioblastoma Stem Cells
- (2015) Jianfeng Han et al. Scientific Reports
- Chloroquine Inhibits Autophagy to Potentiate Antiestrogen Responsiveness in ER+ Breast Cancer
- (2014) K. L. Cook et al. CLINICAL CANCER RESEARCH
- Regulation of Ligands for the NKG2D Activating Receptor
- (2013) David H. Raulet et al. Annual Review of Immunology
- Natural killer cells in intracranial neoplasms: presence and therapeutic efficacy against brain tumours
- (2013) Justyna Kmiecik et al. JOURNAL OF NEURO-ONCOLOGY
- Tumor-Specific Activation of an EGFR-Targeting Probody Enhances Therapeutic Index
- (2013) L. R. Desnoyers et al. Science Translational Medicine
- TGF- downregulates the activating receptor NKG2D on NK cells and CD8+ T cells in glioma patients
- (2011) C. A. Crane et al. NEURO-ONCOLOGY
- Crosstalk between the urokinase-type plasminogen activator receptor and EGF receptor variant III supports survival and growth of glioblastoma cells
- (2011) J. Hu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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