PDGF-D−PDGFRβ signaling enhances IL-15–mediated human natural killer cell survival

An oncolytic virus expressing IL-15/IL-15Rα combined with off-the-shelf EGFR-CAR NK cells targets glioblastoma

(2021) Rui Ma et al.   CANCER RESEARCH

Use of CAR-Transduced Natural Killer Cells in CD19-Positive Lymphoid Tumors

(2020) Enli Liu et al.   NEW ENGLAND JOURNAL OF MEDICINE

Chimeric antigen receptor-engineered natural killer cells for cancer immunotherapy

(2020) Ahmet Yilmaz et al.   Journal of Hematology & Oncology

Chromatin accessibility and the regulatory epigenome

(2019) Sandy L. Klemm et al.   NATURE REVIEWS GENETICS

The mechanism of anti-PD-L1 antibody efficacy against PD-L1 negative tumors identifies NK cells expressing PD-L1 as a cytolytic effector

(2019) Wenjuan Dong et al.   Cancer Discovery

Natural Killer Cells Control Tumor Growth by Sensing a Growth Factor

(2018) Alexander D. Barrow et al.   CELL

Gene Regulatory Programs Conferring Phenotypic Identities to Human NK Cells

(2018) Patrick L. Collins et al.   CELL

The IL-15–AKT–XBP1s signaling pathway contributes to effector functions and survival in human NK cells

(2018) Yufeng Wang et al.   NATURE IMMUNOLOGY

The Broad Spectrum of Human Natural Killer Cell Diversity

(2017) Aharon G. Freud et al.   IMMUNITY

CD56bright NK cells exhibit potent antitumor responses following IL-15 priming

(2017) Julia A. Wagner, Maximillian Rosario, Rizwan Romee, Melissa M. Berrien-Elliott, Stephanie E. Schneider, Jeffrey W. Leong, Ryan P. Sullivan, Brea A. Jewell, Michelle Becker-Hapak, Timothy Schappe, Sara Abdel-Latif, Aaron R. Ireland, Devika Jaishankar, Justin A. King, Ravi Vij, Dennis Clement, Jodie Goodridge, Karl-Johan Malmberg, Hing C. Wong, Todd A. Fehniger   JOURNAL OF CLINICAL INVESTIGATION

Molecular Pathways: Interleukin-15 Signaling in Health and in Cancer

(2014) A. Mishra et al.   CLINICAL CANCER RESEARCH

Human natural killer cell development in secondary lymphoid tissues

(2014) Aharon G. Freud et al.   SEMINARS IN IMMUNOLOGY

Location and cellular stages of natural killer cell development

(2013) Jianhua Yu et al.   TRENDS IN IMMUNOLOGY

Signatures of Human NK Cell Development and Terminal Differentiation

(2013) Merlin Luetke-Eversloh et al.   Frontiers in Immunology

H3K9 and H3K14 acetylation co-occur at many gene regulatory elements, while H3K14ac marks a subset of inactive inducible promoters in mouse embryonic stem cells

(2012) Krishanpal Karmodiya et al.   BMC GENOMICS

Aberrant Overexpression of IL-15 Initiates Large Granular Lymphocyte Leukemia through Chromosomal Instability and DNA Hypermethylation

(2012) Anjali Mishra et al.   CANCER CELL

PDGF-D Improves Drug Delivery and Efficacy via Vascular Normalization, But Promotes Lymphatic Metastasis by Activating CXCR4 in Breast Cancer

(2011) J. Liu et al.   CLINICAL CANCER RESEARCH

NKp46 identifies an NKT cell subset susceptible to leukemic transformation in mouse and human

(2011) Jianhua Yu et al.   JOURNAL OF CLINICAL INVESTIGATION

Platelet-derived growth factor mediates survival of leukemic large granular lymphocytes via an autocrine regulatory pathway

(2009) J. Yang et al.   BLOOD

CD94 surface density identifies a functional intermediary between the CD56bright and CD56dim human NK-cell subsets

(2009) J. Yu et al.   BLOOD

Role of platelet-derived growth factors in physiology and medicine

(2008) J. Andrae et al.   GENES & DEVELOPMENT

Network model of survival signaling in large granular lymphocyte leukemia

(2008) R. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA