Characterization of increased mucus production of HT29-MTX-E12 cells grown under Semi-Wet interface with Mechanical Stimulation

A three-dimensional intestinal tissue model reveals factors and small regulatory RNAs important for colonization with Campylobacter jejuni

(2020) Mona Alzheimer et al.   PLoS Pathogens

Slc26a3 deletion alters pH‐microclimate, mucin biosynthesis, microbiome composition and increases Tnfα expression in murine colon

(2020) A. Kini et al.   Acta Physiologica

Targeting Mechanosensitive Transcription Factors in Atherosclerosis

(2019) Niu Niu et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

A complex human gut microbiome cultured in an anaerobic intestine-on-a-chip

(2019) Sasan Jalili-Firoozinezhad et al.   Nature Biomedical Engineering

ERK5 negatively regulates Kruppel-like factor 4 and promotes osteogenic lineage cell proliferation in response to MEK5 overexpression or fluid shear stress

(2019) Bo Zhang et al.   CONNECTIVE TISSUE RESEARCH

A systematic investigation of the effect of the fluid shear stress on Caco-2 cells towards the optimization of epithelial organ-on-chip models

(2019) Ludivine C. Delon et al.   BIOMATERIALS

Mucus models to evaluate the diffusion of drugs and particles

(2018) Jaclyn Y. Lock et al.   ADVANCED DRUG DELIVERY REVIEWS

Krüppel-like factor 4 (KLF4): What we currently know

(2017) Amr M. Ghaleb et al.   GENE

Transmembrane Mucins: Signaling Receptors at the Intersection of Inflammation and Cancer

(2017) Jos P.M. van Putten et al.   Journal of Innate Immunity

Mucin Cross-Feeding of Infant Bifidobacteria and Eubacterium hallii

(2017) Vera Bunesova et al.   MICROBIAL ECOLOGY

A Notch positive feedback in the intestinal stem cell niche is essential for stem cell self‐renewal

(2017) Kai‐Yuan Chen et al.   Molecular Systems Biology

Microbial Metabolic Networks at the Mucus Layer Lead to Diet-Independent Butyrate and Vitamin B 12 Production by Intestinal Symbionts

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Notch regulation of gastrointestinal stem cells

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Robust bioengineered 3D functional human intestinal epithelium

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Synthetic small intestinal scaffolds for improved studies of intestinal differentiation

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Gastrointestinal Cell Lines Form Polarized Epithelia with an Adherent Mucus Layer when Cultured in Semi-Wet Interfaces with Mechanical Stimulation

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Defining new criteria for selection of cell-based intestinal models using publicly available databases

(2012) Jon Christensen et al.   BMC GENOMICS

Bicarbonate and functional CFTR channel are required for proper mucin secretion and link cystic fibrosis with its mucus phenotype

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Human gut-on-a-chip inhabited by microbial flora that experiences intestinal peristalsis-like motions and flow

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An ex vivo method for studying mucus formation, properties, and thickness in human colonic biopsies and mouse small and large intestinal explants

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Notch signaling modulates proliferation and differentiation of intestinal crypt base columnar stem cells

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Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium

(2011) Toshiro Sato et al.   GASTROENTEROLOGY

Air–liquid interface cultures enhance the oxygen supply and trigger the structural and functional differentiation of intestinal porcine epithelial cells (IPEC)

(2011) Constanze Nossol et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Isolation and in vitro expansion of human colonic stem cells

(2011) Peter Jung et al.   NATURE MEDICINE

Altered intestinal epithelial homeostasis in mice with intestine-specific deletion of the Krüppel-like factor 4 gene

(2010) Amr M. Ghaleb et al.   DEVELOPMENTAL BIOLOGY

MEK5 is Activated by Shear Stress, Activates ERK5 and Induces KLF4 to Modulate TNF Responses in Human Dermal Microvascular Endothelial Cells

(2010) PAUL R. CLARK et al.   MICROCIRCULATION

Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro

(2010) Jason R. Spence et al.   NATURE

The membrane-bound mucins: From cell signalling to transcriptional regulation and expression in epithelial cancers

(2009) Nicolas Jonckheere et al.   BIOCHIMIE

Normal mouse intestinal mucus release requires cystic fibrosis transmembrane regulator–dependent bicarbonate secretion

(2009) Mary Abigail S. Garcia et al.   JOURNAL OF CLINICAL INVESTIGATION

Sustained in vitro intestinal epithelial culture within a Wnt-dependent stem cell niche

(2009) Akifumi Ootani et al.   NATURE MEDICINE

Mouse embryonic fibroblasts null for the Krüppel-like factor 4 gene are genetically unstable

(2009) E G Hagos et al.   ONCOGENE

Roles of Krüppel-like factor 4 in normal homeostasis, cancer and stem cells

(2008) Paul M Evans et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria

(2008) M. E. V. Johansson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA