Quercetin inhibiting the PD ‐1/ PD‐L1 interaction for immune‐enhancing cancer chemopreventive agent

The Role of Anti-PD-1/PD-L1 in the Treatment of Skin Cancer

(2020) James Randall Patrinely et al.   BIODRUGS

Combination Therapy of Doxorubicin and Quercetin on Multidrug-Resistant Breast Cancer and Their Sequential Delivery by Reduction-Sensitive Hyaluronic Acid-Based Conjugate/d-α-Tocopheryl Poly(ethylene glycol) 1000 Succinate Mixed Micelles

(2020) Shuo Liu et al.   MOLECULAR PHARMACEUTICS

PD-1/PD-L1 Based Combinational Cancer Therapy: Icing on the Cake

(2020) Jian-ye Zhang et al.   Frontiers in Pharmacology

Quercetin inhibits TNF-α induced HUVECs apoptosis and inflammation via downregulating NF-kB and AP-1 signaling pathway in vitro

(2020) Tielong Chen et al.   MEDICINE

Quercetin modulates signaling pathways and induces apoptosis in cervical cancer cells

(2019) Madhumitha Kedhari Sundaram et al.   BIOSCIENCE REPORTS

The evolving landscape of ‘next-generation’ immune checkpoint inhibitors: A review

(2019) Luca Mazzarella et al.   EUROPEAN JOURNAL OF CANCER

Progress in PD-1/PD-L1 pathway inhibitors: From biomacromolecules to small molecules

(2019) Xin Lin et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Antitumor and apoptotic effects of quercetin on human melanoma cells involving JNK/P38 MAPK signaling activation

(2019) Sung-Hyun Kim et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Immune Checkpoint PD-1/PD-L1 CTLA-4/CD80 are Blocked by Rhus verniciflua Stokes and its Active Compounds

(2019) Wei Li et al.   MOLECULES

Retreatment with anti‐PD‐1 antibody in non‐small cell lung cancer patients previously treated with anti‐PD‐L1 antibody

(2019) Kohei Fujita et al.   Thoracic Cancer

Quercetin and Quercitrin Attenuates the Inflammatory Response and Oxidative Stress in LPS-Induced RAW264.7 Cells: In Vitro Assessment and a Theoretical Model

(2019) Jie Tang et al.   Biomed Research International

Pharmacological basis and new insights of quercetin action in respect to its anti-cancer effects

(2019) Si-Min Tang et al.   BIOMEDICINE & PHARMACOTHERAPY

Regulation of CD8+ T Cells and Antitumor Immunity by Notch Signaling

(2018) Shin-ichi Tsukumo et al.   Frontiers in Immunology

A patent review on PD-1/PD-L1 antagonists: small molecules, peptides, and macrocycles (2015-2018)

(2018) Shabnam Shaabani et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Fundamental Mechanisms of Immune Checkpoint Blockade Therapy

(2018) Spencer C. Wei et al.   Cancer Discovery

CMTM6 maintains the expression of PD-L1 and regulates anti-tumour immunity

(2017) Marian L. Burr et al.   NATURE

Quercetin inhibits the growth of human gastric cancer stem cells by inducing mitochondrial-dependent apoptosis through the inhibition of PI3K/Akt signaling

(2016) Xinsheng Shen et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Quercetin and Its Anti-Allergic Immune Response

(2016) Jiri Mlcek et al.   MOLECULES

Glycosylation and stabilization of programmed death ligand-1 suppresses T-cell activity

(2016) Chia-Wei Li et al.   Nature Communications

Quercetin, Inflammation and Immunity

(2016) Yao Li et al.   Nutrients

BET Bromodomain Inhibition Promotes Anti-tumor Immunity by Suppressing PD-L1 Expression

(2016) Hengrui Zhu et al.   Cell Reports

PD-1/PD-L1 inhibitors

(2015) Joel Sunshine et al.   CURRENT OPINION IN PHARMACOLOGY

A tetravalent bispecific TandAb (CD19/CD3), AFM11, efficiently recruits T cells for the potent lysis of CD19+tumor cells

(2015) Uwe Reusch et al.   mAbs

Effect of different exposed lights on quercetin and quercetin glucoside content in onion (Allium cepa L.)

(2015) Eun Young Ko et al.   SAUDI JOURNAL OF BIOLOGICAL SCIENCES

Combination of Quercetin and 2-Methoxyestradiol Enhances Inhibition of Human Prostate Cancer LNCaP and PC-3 Cells Xenograft Tumor Growth

(2015) Feiya Yang et al.   PLoS One

A Novel Bispecific Antibody against Human CD3 and Ephrin Receptor A10 for Breast Cancer Therapy

(2015) Shintaro Taki et al.   PLoS One

Quercetin up-regulates mitochondrial complex-I activity to protect against programmed cell death in rotenone model of Parkinson’s disease in rats

(2013) S.S. Karuppagounder et al.   NEUROSCIENCE

The Programmed Death-1 Ligand 1:B7-1 Pathway Restrains Diabetogenic Effector T Cells In Vivo

(2011) A. M. Paterson et al.   JOURNAL OF IMMUNOLOGY

Combination of quercetin with radiotherapy enhances tumor radiosensitivity in vitro and in vivo

(2011) Chenghe Lin et al.   RADIOTHERAPY AND ONCOLOGY

Protective Effect of Quercetin against Arsenite-Induced COX-2 Expression by Targeting PI3K in Rat Liver Epithelial Cells

(2010) Kyung Mi Lee et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Quercetin Enhances Susceptibility to NK Cell-mediated Lysis of Tumor Cells Through Induction of NKG2D Ligands and Suppression of HSP70

(2010) Jae-Ho Bae et al.   JOURNAL OF IMMUNOTHERAPY

Quercetin regulates Th1/Th2 balance in a murine model of asthma

(2008) Hee-ju Park et al.   INTERNATIONAL IMMUNOPHARMACOLOGY