Protective effect of isosteviol sodium against LPS-induced multiple organ injury by regulating of glycerophospholipid metabolism and reducing macrophage-driven inflammation

Metabolic aspects of muscle wasting during critical illness

(2020) Robert J.J. van Gassel et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Long noncoding RNA colorectal neoplasia differentially expressed alleviates sepsis‐induced liver injury via regulating miR‐126‐5p

(2020) Yang Li et al.   IUBMB LIFE

Global, regional, and national sepsis incidence and mortality, 1990–2017: analysis for the Global Burden of Disease Study

(2020) Kristina E Rudd et al.   LANCET

Glycogen metabolism regulates macrophage-mediated acute inflammatory responses

(2020) Jingwei Ma et al.   Nature Communications

Metabolomic Insights Into the Synergistic Effect of Biapenem in Combination With Xuebijing Injection Against Sepsis

(2020) Li-Wei Liu et al.   Frontiers in Pharmacology

Potential of glucocorticoids to treat intestinal inflammation during sepsis

(2020) Kelly Van Looveren et al.   CURRENT OPINION IN PHARMACOLOGY

Overexpressing TGF-β1 in mesenchymal stem cells attenuates organ dysfunction during CLP-induced septic mice by reducing macrophage-driven inflammation

(2020) Feng Liu et al.   Stem Cell Research & Therapy

miR-146a targeted to splenic macrophages prevents sepsis-induced multiple organ injury

(2019) Yoshio Funahashi et al.   LABORATORY INVESTIGATION

Innate immunity to intracellular LPS

(2019) Vijay A. K. Rathinam et al.   NATURE IMMUNOLOGY

Tutorial on lipidomics

(2019) Jianing Wang et al.   ANALYTICA CHIMICA ACTA

Acute kidney injury from sepsis: current concepts, epidemiology, pathophysiology, prevention and treatment

(2019) Sadudee Peerapornratana et al.   KIDNEY INTERNATIONAL

Toward Increased Understanding of the Steroid Controversy in Septic Shock

(2019) James A. Russell et al.   CRITICAL CARE MEDICINE

Prognostic and predictive enrichment in sepsis

(2019) Natalja L. Stanski et al.   Nature Reviews Nephrology

Impact and Beneficial Critical Points of Clinical Outcome in Corticosteroid Management of Adult Patients With Sepsis: Meta-Analysis and GRADE Assessment

(2019) Lu-Lu Lin et al.   Frontiers in Pharmacology

STVNa attenuates right ventricle hypertrophy and pulmonary artery remodeling in rats induced by transverse aortic constriction

(2018) Qing Liu et al.   BIOMEDICINE & PHARMACOTHERAPY

Biomarkers in Sepsis

(2018) Tjitske S.R. van Engelen et al.   CRITICAL CARE CLINICS

Reprogramming of basic metabolic pathways in microbial sepsis: therapeutic targets at last?

(2018) Lise Van Wyngene et al.   EMBO Molecular Medicine

Long-term impact of sepsis on cardiovascular health

(2018) R. T. Mankowski et al.   INTENSIVE CARE MEDICINE

Isosteviol ameliorates diabetic cardiomyopathy in rats by inhibiting ERK and NF-κB signaling pathways

(2018) Sheng-Gao Tang et al.   JOURNAL OF ENDOCRINOLOGY

Sepsis and septic shock

(2018) Maurizio Cecconi et al.   LANCET

Effects of melatonin on low dose lipopolysaccharide-induced oxidative stress in the mouse liver, muscle and kidney

(2018) Natalia Kurhaluk et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Isosteviol protects free fatty acid- and high fat diet-induced hepatic injury via modulating PKC-β/p66Shc/ROS and ER stress pathways

(2018) Hongwei Yi et al.   ANTIOXIDANTS & REDOX SIGNALING

Hippocampus and cerebellum damage in sepsis induced by lipopolysaccharide in aged rats - Pregabalin can prevent damage

(2018) Rahime Aslankoc et al.   BIOMEDICINE & PHARMACOTHERAPY

Isosteviol Sodium Protects Against Permanent Cerebral Ischemia Injury in Mice via Inhibition of NF-κB–Mediated Inflammatory and Apoptotic Responses

(2017) Hao Zhang et al.   Journal of Stroke & Cerebrovascular Diseases

Cytokine storm and sepsis disease pathogenesis

(2017) Benjamin G. Chousterman et al.   Seminars in Immunopathology

Isosteviol Sodium Protects Against Permanent Cerebral Ischemia Injury in Mice via Inhibition of NF-κB–Mediated Inflammatory and Apoptotic Responses

(2017) Hao Zhang et al.   Journal of Stroke & Cerebrovascular Diseases

Metabolite Profiles in Sepsis

(2016) Sophie Neugebauer et al.   CRITICAL CARE MEDICINE

Functional crosstalk between membrane lipids and TLR biology

(2016) Marielle S Köberlin et al.   CURRENT OPINION IN CELL BIOLOGY

Synthesis, cytotoxic activity evaluation and HQSAR study of novel isosteviol derivatives as potential anticancer agents

(2016) Cong-Jun Liu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Lipopolysaccharide-Induced CD300b Receptor Binding to Toll-like Receptor 4 Alters Signaling to Drive Cytokine Responses that Enhance Septic Shock

(2016) Oliver H. Voss et al.   IMMUNITY

Blocking NAD+/CD38/cADPR/Ca2+ pathway in sepsis prevents organ damage

(2016) Qian-Yi Peng et al.   JOURNAL OF SURGICAL RESEARCH

Emerging applications of metabolomics in drug discovery and precision medicine

(2016) David S. Wishart   NATURE REVIEWS DRUG DISCOVERY

Metabolomics: beyond biomarkers and towards mechanisms

(2016) Caroline H. Johnson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Isosteviol Sensitizes sarcKATPChannels towards Pinacidil and Potentiates Mitochondrial Uncoupling of Diazoxide in Guinea Pig Ventricular Myocytes

(2016) Zhuo Fan et al.   Oxidative Medicine and Cellular Longevity

Protection of baicalin against lipopolysaccharide induced liver and kidney injuries based on 1H NMR metabolomic profiling

(2016) Shanting Liao et al.   Toxicology Research

A Blood-brain Barrier Permeable Derivative of 5-Fluorouracil: Preparation, Intracellular Localization, and Mouse Tissue Distribution

(2011) Jung-Kyun Im et al.   BULLETIN OF THE KOREAN CHEMICAL SOCIETY

Isosteviol increases insulin sensitivity and changes gene expression of key insulin regulatory genes and transcription factors in islets of the diabetic KKAy mouse

(2008) I. Nordentoft et al.   DIABETES OBESITY & METABOLISM

Dexamethasone inhibits lipopolysaccharide-induced hydrogen sulphide biosynthesis in intact cells and in an animal model of endotoxic shock

(2008) Ling Li et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE