Chemical exchange saturation transfer imaging of creatine, phosphocreatine, and protein arginine residue in tissues

Brain pH imaging and its applications

(2021) Hahnsung Kim et al.   NEUROSCIENCE

Whole‐brain amide CEST imaging at 3T with a steady‐state radial MRI acquisition

(2021) Ran Sui et al.   MAGNETIC RESONANCE IN MEDICINE

Role of chemical exchange on the relayed nuclear Overhauser enhancement signal in saturation transfer MRI

(2021) Tao Jin et al.   MAGNETIC RESONANCE IN MEDICINE

Early detection of Alzheimer's disease using creatine chemical exchange saturation transfer magnetic resonance imaging

(2021) Lin Chen et al.   NEUROIMAGE

Comparative evaluation of polynomial and Lorentzian lineshape‐fitted amine CEST imaging in acute ischemic stroke

(2021) Jing Cui et al.   MAGNETIC RESONANCE IN MEDICINE

In vivo imaging of phosphocreatine with artificial neural networks

(2020) Lin Chen et al.   Nature Communications

Whole brain snapshot CEST at 3T using 3D‐EPI: Aiming for speed, volume, and homogeneity

(2020) Sebastian Mueller et al.   MAGNETIC RESONANCE IN MEDICINE

High‐sensitivity CEST mapping using a spatiotemporal correlation‐enhanced method

(2020) Lin Chen et al.   MAGNETIC RESONANCE IN MEDICINE

Relayed nuclear Overhauser enhancement imaging with magnetization transfer contrast suppression at 3 T

(2020) Jianpan Huang et al.   MAGNETIC RESONANCE IN MEDICINE

Recovery kinetics of creatine in mild plantar flexion exercise using 3D creatine CEST imaging at 7 Tesla

(2020) Dushyant Kumar et al.   MAGNETIC RESONANCE IN MEDICINE

Mechanism and quantitative assessment of saturation transfer for water‐based detection of the aliphatic protons in carbohydrate polymers

(2020) Yang Zhou et al.   MAGNETIC RESONANCE IN MEDICINE

pH Mapping of Skeletal Muscle by Chemical Exchange Saturation Transfer (CEST) Imaging

(2020) Yu-Wen Chen et al.   Cells

APT-weighted MRI: Techniques, current neuro applications, and challenging issues

(2019) Jinyuan Zhou et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

DeepCEST: 9.4 T Chemical exchange saturation transfer MRI contrast predicted from 3 T data - a proof of concept study

(2019) Moritz Zaiss et al.   MAGNETIC RESONANCE IN MEDICINE

Chemical exchange saturation transfer imaging of phosphocreatine in the muscle

(2019) Julius Juhyun Chung et al.   MAGNETIC RESONANCE IN MEDICINE

Approximated analytical characterization of the steady-state chemical exchange saturation transfer (CEST) signals

(2019) Tao Jin et al.   MAGNETIC RESONANCE IN MEDICINE

High‐resolution creatine mapping of mouse brain at 11.7 T using non‐steady‐state chemical exchange saturation transfer

(2019) Lin Chen et al.   NMR IN BIOMEDICINE

Extracellular pH mapping of liver cancer on a clinical 3T MRI scanner

(2019) Daniel Coman et al.   MAGNETIC RESONANCE IN MEDICINE

Towards the molecular origin of glutamate CEST (GluCEST) imaging in rat brain

(2019) Jing Cui et al.   MAGNETIC RESONANCE IN MEDICINE

Normal brain aging and Alzheimer’s disease are associated with lower cerebral pH: an in vivo histidine 1H-MR spectroscopy study

(2019) Epameinondas Lyros et al.   NEUROBIOLOGY OF AGING

DeepCEST 3T: Robust MRI parameter determination and uncertainty quantification with neural networks—application to CEST imaging of the human brain at 3T

(2019) Felix Glang et al.   MAGNETIC RESONANCE IN MEDICINE

A Polymer Dots-Based Photoelectrochemical pH Sensor: Simplicity, High Sensitivity, and Broad-Range pH Measurement

(2018) Xiao-Mei Shi et al.   ANALYTICAL CHEMISTRY

Separating fast and slow exchange transfer and magnetization transfer using off-resonance variable-delay multiple-pulse (VDMP) MRI

(2018) Lin Chen et al.   MAGNETIC RESONANCE IN MEDICINE

Magnetization Transfer Contrast and Chemical Exchange Saturation Transfer MRI. Features and analysis of the field-dependent saturation spectrum

(2018) Peter C.M. van Zijl et al.   NEUROIMAGE

Determination of multipool contributions to endogenous amide proton transfer effects in global ischemia with high spectral resolution in vivo chemical exchange saturation transfer MRI

(2018) Iris Yuwen Zhou et al.   MAGNETIC RESONANCE IN MEDICINE

Creatine and phosphocreatine mapping of mouse skeletal muscle by a polynomial and Lorentzian line-shape fitting CEST method

(2018) Lin Chen et al.   MAGNETIC RESONANCE IN MEDICINE

Image reconstruction by domain-transform manifold learning

(2018) Bo Zhu et al.   NATURE

Protein aggregation linked to Alzheimer's disease revealed by saturation transfer MRI

(2018) Lin Chen et al.   NEUROIMAGE

Amide proton transfer-weighted magnetic resonance image-guided stereotactic biopsy in patients with newly diagnosed gliomas

(2017) Shanshan Jiang et al.   EUROPEAN JOURNAL OF CANCER

Imaging the physiological evolution of the ischemic penumbra in acute ischemic stroke

(2017) Richard Leigh et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Clinical applications of chemical exchange saturation transfer (CEST) MRI

(2017) Kyle M. Jones et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

Dynamic phosphocreatine imaging with unlocalized pH assessment of the human lower leg muscle following exercise at 3T

(2017) Oleksandr Khegai et al.   MAGNETIC RESONANCE IN MEDICINE

Assignment of the molecular origins of CEST signals at 2 ppm in rat brain

(2017) Xiao-Yong Zhang et al.   MAGNETIC RESONANCE IN MEDICINE

Improving the detection sensitivity of pH-weighted amide proton transfer MRI in acute stroke patients using extrapolated semisolid magnetization transfer reference signals

(2017) Hye-Young Heo et al.   MAGNETIC RESONANCE IN MEDICINE

Enhancing sensitivity of pH-weighted MRI with combination of amide and guanidyl CEST

(2017) Tao Jin et al.   NEUROIMAGE

Investigation of the contribution of total creatine to the CEST Z -spectrum of brain using a knockout mouse model

(2017) Lin Chen et al.   NMR IN BIOMEDICINE

Brain Tumor Segmentation Using Convolutional Neural Networks in MRI Images

(2016) Sergio Pereira et al.   IEEE TRANSACTIONS ON MEDICAL IMAGING

Automatic Detection of Cerebral Microbleeds From MR Images via 3D Convolutional Neural Networks

(2016) Qi Dou et al.   IEEE TRANSACTIONS ON MEDICAL IMAGING

Downfield-NOE-suppressed amide-CEST-MRI at 7 Tesla provides a unique contrast in human glioblastoma

(2016) Moritz Zaiss et al.   MAGNETIC RESONANCE IN MEDICINE

Creatine CEST MRI for Differentiating Gliomas with Different Degrees of Aggressiveness

(2016) Kejia Cai et al.   MOLECULAR IMAGING AND BIOLOGY

Dynamic31P-MRSI using spiral spectroscopic imaging can map mitochondrial capacity in muscles of the human calf during plantar flexion exercise at 7 T

(2016) Ladislav Valkovič et al.   NMR IN BIOMEDICINE

Simulation, phantom validation, and clinical evaluation of fast pH-weighted molecular imaging using amine chemical exchange saturation transfer echo planar imaging (CEST-EPI) in glioma at 3 T

(2016) Robert J. Harris et al.   NMR IN BIOMEDICINE

Altered brain arginine metabolism in schizophrenia

(2016) P Liu et al.   Translational Psychiatry

Lactate Chemical Exchange Saturation Transfer (LATEST) Imaging in vivo: A Biomarker for LDH Activity

(2016) Catherine DeBrosse et al.   Scientific Reports

A method for accurate pH mapping with chemical exchange saturation transfer (CEST) MRI

(2015) Phillip Zhe Sun et al.   Contrast Media & Molecular Imaging

Quantitative assessment of amide proton transfer (APT) and nuclear overhauser enhancement (NOE) imaging with extrapolated semi-solid magnetization transfer reference (EMR) signals: Application to a rat glioma model at 4.7 tesla

(2015) Hye-Young Heo et al.   MAGNETIC RESONANCE IN MEDICINE

Magnetization transfer contrast-suppressed imaging of amide proton transfer and relayed nuclear overhauser enhancement chemical exchange saturation transfer effects in the human brain at 7T

(2015) Xiang Xu et al.   MAGNETIC RESONANCE IN MEDICINE

Assessment of lymphatic impairment and interstitial protein accumulation in patients with breast cancer treatment-related lymphedema using CEST MRI

(2015) Manus J. Donahue et al.   MAGNETIC RESONANCE IN MEDICINE

Dynamic PCr and pH imaging of human calf muscles during exercise and recovery using31P gradient-Echo MRI at 7 Tesla

(2015) Albrecht Ingo Schmid et al.   MAGNETIC RESONANCE IN MEDICINE

Localized semi-LASER dynamic 31P magnetic resonance spectroscopy of the soleus during and following exercise at 7 T

(2015) Georg B. Fiedler et al.   MAGNETIC RESONANCE MATERIALS IN PHYSICS BIOLOGY AND MEDICINE

Relaxation-compensated CEST-MRI at 7 T for mapping of creatine content and pH - preliminary application in human muscle tissuein vivo

(2015) Eugenia Rerich et al.   NMR IN BIOMEDICINE

Correction ofB1-inhomogeneities for relaxation-compensated CEST imaging at 7 T

(2015) Johannes Windschuh et al.   NMR IN BIOMEDICINE

Rapid assessment of quantitativeT1,T2andT2* in lower extremity muscles in response to maximal treadmill exercise

(2015) Juliet Varghese et al.   NMR IN BIOMEDICINE

Glutamate imaging (GluCEST) lateralizes epileptic foci in nonlesional temporal lobe epilepsy

(2015) Kathryn Adamiak Davis et al.   Science Translational Medicine

Chemical exchange saturation transfer MR imaging of Parkinson’s disease at 3 Tesla

(2014) Chunmei Li et al.   EUROPEAN RADIOLOGY

A technique for in vivo mapping of myocardial creatine kinase metabolism

(2014) Mohammad Haris et al.   NATURE MEDICINE

Exercising calf muscle T2∗ changes correlate with pH, PCr recovery and maximum oxidative phosphorylation

(2014) Albrecht Ingo Schmid et al.   NMR IN BIOMEDICINE

Characterization of creatine guanidinium proton exchange by water-exchange (WEX) spectroscopy for absolute-pH CEST imagingin vitro

(2014) Steffen Goerke et al.   NMR IN BIOMEDICINE

Advantages of chemical exchange-sensitive spin-lock (CESL) over chemical exchange saturation transfer (CEST) for hydroxyl- and amine-water proton exchange studies

(2014) Tao Jin et al.   NMR IN BIOMEDICINE

Optical Chemical pH Sensors

(2013) Dorota Wencel et al.   ANALYTICAL CHEMISTRY

In vivo chemical exchange saturation transfer imaging of creatine (CrCEST) in skeletal muscle at 3T

(2013) Feliks Kogan et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

Method for high-resolution imaging of creatine in vivo using chemical exchange saturation transfer

(2013) Feliks Kogan et al.   MAGNETIC RESONANCE IN MEDICINE

APT-weighted and NOE-weighted image contrasts in glioma with different RF saturation powers based on magnetization transfer ratio asymmetry analyses

(2013) Jinyuan Zhou et al.   MAGNETIC RESONANCE IN MEDICINE

Sensitivity and Source of Amine-Proton Exchange and Amide-Proton Transfer Magnetic Resonance Imaging in Cerebral Ischemia

(2013) Xiaopeng Zong et al.   MAGNETIC RESONANCE IN MEDICINE

Variable delay multi-pulse train for fast chemical exchange saturation transfer and relayed-nuclear overhauser enhancement MRI

(2013) Jiadi Xu et al.   MAGNETIC RESONANCE IN MEDICINE

Mapping of amide, amine, and aliphatic peaks in the CEST spectra of murine xenografts at 7 T

(2013) Kimberly L. Desmond et al.   MAGNETIC RESONANCE IN MEDICINE

Biochemical, molecular, and clinical diagnoses of patients with cerebral creatine deficiency syndromes

(2013) Matthew S. Comeaux et al.   MOLECULAR GENETICS AND METABOLISM

Nuclear Overhauser enhancement (NOE) imaging in the human brain at 7T

(2013) Craig K. Jones et al.   NEUROIMAGE

Nuts and bolts of chemical exchange saturation transfer MRI

(2013) Guanshu Liu et al.   NMR IN BIOMEDICINE

Chemical exchange saturation transfer (CEST) and MRZ-spectroscopyin vivo: a review of theoretical approaches and methods

(2013) Moritz Zaiss et al.   PHYSICS IN MEDICINE AND BIOLOGY

MICEST: A potential tool for non-invasive detection of molecular changes in Alzheimer's disease

(2012) Mohammad Haris et al.   JOURNAL OF NEUROSCIENCE METHODS

MR imaging of the amide-proton transfer effect and the pH-insensitive nuclear overhauser effect at 9.4 T

(2012) Tao Jin et al.   MAGNETIC RESONANCE IN MEDICINE

Magnetic resonance imaging of glutamate

(2012) Kejia Cai et al.   NATURE MEDICINE

Exchange-dependent relaxation in the rotating frame for slow and intermediate exchange - modeling off-resonant spin-lock and chemical exchange saturation transfer

(2012) Moritz Zaiss et al.   NMR IN BIOMEDICINE

Exchange rates of creatine kinase metabolites: feasibility of imaging creatine by chemical exchange saturation transfer MRI

(2012) Mohammad Haris et al.   NMR IN BIOMEDICINE

Amide proton transfer MR imaging of prostate cancer: A preliminary study

(2011) Guang Jia et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

Chemical exchange saturation transfer (CEST): What is in a name and what isn't?

(2011) Peter C. M. van Zijl et al.   MAGNETIC RESONANCE IN MEDICINE

Magnetic resonance imaging of the Amine–Proton EXchange (APEX) dependent contrast

(2011) Tao Jin et al.   NEUROIMAGE

Muscle energetics changes throughout maturation: a quantitative 31P-MRS analysis

(2010) Anne Tonson et al.   JOURNAL OF APPLIED PHYSIOLOGY

Spin-locking versus chemical exchange saturation transfer MRI for investigating chemical exchange process between water and labile metabolite protons

(2010) Tao Jin et al.   MAGNETIC RESONANCE IN MEDICINE

Differentiation between glioma and radiation necrosis using molecular magnetic resonance imaging of endogenous proteins and peptides

(2010) Jinyuan Zhou et al.   NATURE MEDICINE

Pushing the Sensitivity Envelope of Lanthanide-Based Magnetic Resonance Imaging (MRI) Contrast Agents for Molecular Imaging Applications

(2009) Silvio Aime et al.   ACCOUNTS OF CHEMICAL RESEARCH

Functions and effects of creatine in the central nervous system

(2008) Robert H. Andres et al.   BRAIN RESEARCH BULLETIN

New “multicolor” polypeptide diamagnetic chemical exchange saturation transfer (DIACEST) contrast agents for MRI

(2008) Michael T. McMahon et al.   MAGNETIC RESONANCE IN MEDICINE

Investigation of optimizing and translating pH-sensitive pulsed-chemical exchange saturation transfer (CEST) imaging to a 3T clinical scanner

(2008) Phillip Zhe Sun et al.   MAGNETIC RESONANCE IN MEDICINE

Practical data acquisition method for human brain tumor amide proton transfer (APT) imaging

(2008) Jinyuan Zhou et al.   MAGNETIC RESONANCE IN MEDICINE

Assessment of glycosaminoglycan concentration in vivo by chemical exchange-dependent saturation transfer (gagCEST)

(2008) W. Ling et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Electrochemical Sensors Based on Organic Conjugated Polymers

(2008) Md. Rahman et al.   SENSORS