Clinical applications of chemical exchange saturation transfer (CEST) MRI

Assessment of the patellofemoral cartilage: Correlation of knee pain score with magnetic resonance cartilage grading and magnetization transfer ratio asymmetry of glycosaminoglycan chemical exchange saturation transfer

(2017) Young Han Lee et al.   MAGNETIC RESONANCE IMAGING

The role of amide proton transfer imaging in detecting active malignant glioma.

(2017) J. O. Blakeley et al.   JOURNAL OF CLINICAL ONCOLOGY

Detection of Sulfatase Enzyme Activity with a CatalyCEST MRI Contrast Agent

(2016) Sanhita Sinharay et al.   CHEMISTRY-A EUROPEAN JOURNAL

Developing imidazoles as CEST MRI pH sensors

(2016) Xing Yang et al.   Contrast Media & Molecular Imaging

A theoretical analysis of chemical exchange saturation transfer echo planar imaging (CEST-EPI) steady state solution and the CEST sensitivity efficiency-based optimization approach

(2016) Weiping Jiang et al.   Contrast Media & Molecular Imaging

Added value of amide proton transfer imaging to conventional and perfusion MR imaging for evaluating the treatment response of newly diagnosed glioblastoma

(2016) Kye Jin Park et al.   EUROPEAN RADIOLOGY

Design and optimization of pulsed Chemical Exchange Saturation Transfer MRI using a multiobjective genetic algorithm

(2016) Eriko S. Yoshimaru et al.   JOURNAL OF MAGNETIC RESONANCE

QUESPOWR MRI: QUantification of Exchange as a function of Saturation Power On the Water Resonance

(2016) Edward A. Randtke et al.   JOURNAL OF MAGNETIC RESONANCE

Glycosaminoglycan chemical exchange saturation transfer in human lumbar intervertebral discs: Effect of saturation pulse and relationship with low back pain

(2016) Tatsuhiro Wada et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

Applying amide proton transfer-weighted MRI to distinguish pseudoprogression from true progression in malignant gliomas

(2016) Bo Ma et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

Topiramate induces acute intracellular acidification in glioblastoma

(2016) Kamini Marathe et al.   JOURNAL OF NEURO-ONCOLOGY

Gender, BMI and T2 dependencies of glycosaminoglycan chemical exchange saturation transfer in intervertebral discs

(2016) Anja Müller-Lutz et al.   MAGNETIC RESONANCE IMAGING

High quality three-dimensional gagCEST imaging of in vivo human knee cartilage at 7 Tesla

(2016) Guruprasad Krishnamoorthy et al.   MAGNETIC RESONANCE IN MEDICINE

Downfield-NOE-suppressed amide-CEST-MRI at 7 Tesla provides a unique contrast in human glioblastoma

(2016) Moritz Zaiss et al.   MAGNETIC RESONANCE IN MEDICINE

Accelerating chemical exchange saturation transfer (CEST) MRI by combining compressed sensing and sensitivity encoding techniques

(2016) Hye-Young Heo et al.   MAGNETIC RESONANCE IN MEDICINE

Noninvasive detection of enzyme activity in tumor models of human ovarian cancer using catalyCEST MRI

(2016) Sanhita Sinharay et al.   MAGNETIC RESONANCE IN MEDICINE

On-resonance variable delay multipulse scheme for imaging of fast-exchanging protons and semisolid macromolecules

(2016) Jiadi Xu et al.   MAGNETIC RESONANCE IN MEDICINE

Reproducibility and regional variations of an improved gagCEST protocol for the in vivo evaluation of knee cartilage at 7 T

(2016) Markus M. Schreiner et al.   MAGNETIC RESONANCE MATERIALS IN PHYSICS BIOLOGY AND MEDICINE

Clinical Translation of Tumor Acidosis Measurements with AcidoCEST MRI

(2016) Kyle M. Jones et al.   MOLECULAR IMAGING AND BIOLOGY

Aggregation-induced changes in the chemical exchange saturation transfer (CEST) signals of proteins

(2016) Steffen Goerke et al.   NMR IN BIOMEDICINE

Chemical exchange saturation transfer of the cervical spinal cord at 7 T

(2016) Adrienne N. Dula et al.   NMR IN BIOMEDICINE

Perfusion has no effect on thein vivoCEST effect from Cr (CrCEST) in skeletal muscle

(2016) Feliks Kogan et al.   NMR IN BIOMEDICINE

Simulation, phantom validation, and clinical evaluation of fast pH-weighted molecular imaging using amine chemical exchange saturation transfer echo planar imaging (CEST-EPI) in glioma at 3 T

(2016) Robert J. Harris et al.   NMR IN BIOMEDICINE

Facet tropism and facet joint orientation: risk factors for the development of early biochemical alterations of lumbar intervertebral discs

(2016) C. Schleich et al.   OSTEOARTHRITIS AND CARTILAGE

Glycosaminoglycan Chemical Exchange Saturation Transfer of Lumbar Intervertebral Discs in Healthy Volunteers

(2016) Christoph Schleich et al.   SPINE

Assessing Metabolic Changes in Response to mTOR Inhibition in a Mantle Cell Lymphoma Xenograft Model Using AcidoCEST MRI

(2016) Paul J. Akhenblit et al.   Molecular Imaging

Lactate Chemical Exchange Saturation Transfer (LATEST) Imaging in vivo: A Biomarker for LDH Activity

(2016) Catherine DeBrosse et al.   Scientific Reports

Magnetic Resonance Imaging of Glucose Uptake and Metabolism in Patients with Head and Neck Cancer

(2016) Jihong Wang et al.   Scientific Reports

Glucosamine and N-acetyl glucosamine as new CEST MRI agents for molecular imaging of tumors

(2016) Michal Rivlin et al.   Scientific Reports

Chemical Exchange Saturation Transfer (CEST) Agents: Quantum Chemistry and MRI

(2015) Jikun Li et al.   CHEMISTRY-A EUROPEAN JOURNAL

A single diamagnetic catalyCEST MRI contrast agent that detects cathepsin B enzyme activity by using a ratio of two CEST signals

(2015) Dina V. Hingorani et al.   Contrast Media & Molecular Imaging

A review of optimization and quantification techniques for chemical exchange saturation transfer MRI toward sensitive in vivo imaging

(2015) Jinsuh Kim et al.   Contrast Media & Molecular Imaging

A comparison of iopromide and iopamidol, two acidoCEST MRI contrast media that measure tumor extracellular pH

(2015) Brianna F. Moon et al.   Contrast Media & Molecular Imaging

Glycosaminoglycan chemical exchange saturation transfer of lumbar intervertebral discs in patients with spondyloarthritis

(2015) Christoph Schleich et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

Whole-brain amide proton transfer (APT) and nuclear overhauser enhancement (NOE) imaging in glioma patients using low-power steady-state pulsed chemical exchange saturation transfer (CEST) imaging at 7T

(2015) Hye-Young Heo et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

Simultaneous detection and separation of hyperacute intracerebral hemorrhage and cerebral ischemia using amide proton transfer MRI

(2015) Meiyun Wang et al.   MAGNETIC RESONANCE IN MEDICINE

UCEPR: Ultrafast localized CEST-spectroscopy with PRESS in phantoms and in vivo

(2015) Zheng Liu et al.   MAGNETIC RESONANCE IN MEDICINE

Magnetization transfer contrast-suppressed imaging of amide proton transfer and relayed nuclear overhauser enhancement chemical exchange saturation transfer effects in the human brain at 7T

(2015) Xiang Xu et al.   MAGNETIC RESONANCE IN MEDICINE

Assessment of lymphatic impairment and interstitial protein accumulation in patients with breast cancer treatment-related lymphedema using CEST MRI

(2015) Manus J. Donahue et al.   MAGNETIC RESONANCE IN MEDICINE

Chemical Exchange Saturation Transfer (CEST) MR Technique for Liver Imaging at 3.0 Tesla: an Evaluation of Different Offset Number and an After-Meal and Over-Night-Fast Comparison

(2015) Min Deng et al.   MOLECULAR IMAGING AND BIOLOGY

Assessing Amide Proton Transfer (APT) MRI Contrast Origins in 9 L Gliosarcoma in the Rat Brain Using Proteomic Analysis

(2015) Kun Yan et al.   MOLECULAR IMAGING AND BIOLOGY

Evaluations of Tumor Acidosis Within In Vivo Tumor Models Using Parametric Maps Generated with AcidoCEST MRI

(2015) Liu Qi Chen et al.   MOLECULAR IMAGING AND BIOLOGY

Relaxation-compensated CEST-MRI of the human brain at 7 T: Unbiased insight into NOE and amide signal changes in human glioblastoma

(2015) Moritz Zaiss et al.   NEUROIMAGE

In vivo imaging of tau pathology using multi-parametric quantitative MRI

(2015) J.A. Wells et al.   NEUROIMAGE

Relaxation-compensated CEST-MRI at 7 T for mapping of creatine content and pH - preliminary application in human muscle tissuein vivo

(2015) Eugenia Rerich et al.   NMR IN BIOMEDICINE

Correction ofB1-inhomogeneities for relaxation-compensated CEST imaging at 7 T

(2015) Johannes Windschuh et al.   NMR IN BIOMEDICINE

Fast simulation and optimization of pulse-train chemical exchange saturation transfer (CEST) imaging

(2015) Gang Xiao et al.   PHYSICS IN MEDICINE AND BIOLOGY

Glutamate imaging (GluCEST) lateralizes epileptic foci in nonlesional temporal lobe epilepsy

(2015) Kathryn Adamiak Davis et al.   Science Translational Medicine

Biochemical imaging of cervical intervertebral discs with glycosaminoglycan chemical exchange saturation transfer magnetic resonance imaging: feasibility and initial results

(2015) Christoph Schleich et al.   SKELETAL RADIOLOGY

Identifying the ischaemic penumbra using pH-weighted magnetic resonance imaging

(2015) George W. J. Harston et al.   BRAIN

Tuning Phenols with Intra-Molecular Bond Shifted HYdrogens (IM-SHY) as diaCEST MRI Contrast Agents

(2014) Xing Yang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Anthranilic acid analogs as diamagnetic CEST MRI contrast agents that feature an intramolecular-bond shifted hydrogen

(2014) Xiaolei Song et al.   Contrast Media & Molecular Imaging

A review of responsive MRI contrast agents: 2005-2014

(2014) Dina V. Hingorani et al.   Contrast Media & Molecular Imaging

Quantitative Tissue Ph Measurement during Cerebral Ischemia Using Amine and Amide Concentration-Independent Detection (AACID) with MRI

(2014) Nevin McVicar et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Functional molecular imaging of tumors by chemical exchange saturation transfer MRI of 3-O-Methyl-D-glucose

(2014) Michal Rivlin et al.   MAGNETIC RESONANCE IN MEDICINE

Pilot study of Iopamidol-based quantitative pH imaging on a clinical 3T MR scanner

(2014) Anja Müller-Lutz et al.   MAGNETIC RESONANCE MATERIALS IN PHYSICS BIOLOGY AND MEDICINE

Contributors to contrast between glioma and brain tissue in chemical exchange saturation transfer sensitive imaging at 3Tesla

(2014) Rachel Scheidegger et al.   NEUROIMAGE

Comparing different analysis methods for quantifying the MRI amide proton transfer (APT) effect in hyperacute stroke patients

(2014) Y. K. Tee et al.   NMR IN BIOMEDICINE

InverseZ-spectrum analysis for spillover-, MT-, andT1-corrected steady-state pulsed CEST-MRI - application to pH-weighted MRI of acute stroke

(2014) Moritz Zaiss et al.   NMR IN BIOMEDICINE

A combined analytical solution for chemical exchange saturation transfer and semi-solid magnetization transfer

(2014) Moritz Zaiss et al.   NMR IN BIOMEDICINE

Comparison of biochemical cartilage imaging techniques at 3 T MRI

(2014) C. Rehnitz et al.   OSTEOARTHRITIS AND CARTILAGE

Magnetization Transfer Prepared Gradient Echo MRI for CEST Imaging

(2014) Zhuozhi Dai et al.   PLoS One

Ultrafast Scanning of Exchangeable Sites by NMR Spectroscopy

(2013) Xiang Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Salicylic Acid and Analogues as diaCEST MRI Contrast Agents with Highly Shifted Exchangeable Proton Frequencies

(2013) Xing Yang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Comparison of divalent transition metal ion paraCEST MRI contrast agents

(2013) Sarina J. Dorazio et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Three-dimensional amide proton transfer MR imaging of gliomas: Initial experience and comparison with gadolinium enhancement

(2013) Jinyuan Zhou et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

Quantification of amide proton transfer effect pre- and post-gadolinium contrast agent administration

(2013) Yee Kai Tee et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

In vivo chemical exchange saturation transfer imaging of creatine (CrCEST) in skeletal muscle at 3T

(2013) Feliks Kogan et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

A CatalyCEST MRI Contrast Agent That Detects the Enzyme-Catalyzed Creation of a Covalent Bond

(2013) Dina V. Hingorani et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Method for high-resolution imaging of creatine in vivo using chemical exchange saturation transfer

(2013) Feliks Kogan et al.   MAGNETIC RESONANCE IN MEDICINE

Variable delay multi-pulse train for fast chemical exchange saturation transfer and relayed-nuclear overhauser enhancement MRI

(2013) Jiadi Xu et al.   MAGNETIC RESONANCE IN MEDICINE

Imaging of Endogenous Exchangeable Proton Signals in the Human Brain Using Frequency Labeled Exchange Transfer Imaging

(2013) Nirbhay N. Yadav et al.   MAGNETIC RESONANCE IN MEDICINE

Evaluations of extracellular pH within in vivo tumors using acidoCEST MRI

(2013) Liu Qi Chen et al.   MAGNETIC RESONANCE IN MEDICINE

In vivo imaging of glucose uptake and metabolism in tumors

(2013) Simon Walker-Samuel et al.   NATURE MEDICINE

Amide proton transfer imaging of adult diffuse gliomas: correlation with histopathological grades

(2013) O. Togao et al.   NEURO-ONCOLOGY

Imaging of glutamate in the spinal cord using GluCEST

(2013) Feliks Kogan et al.   NEUROIMAGE

Nuclear Overhauser enhancement (NOE) imaging in the human brain at 7T

(2013) Craig K. Jones et al.   NEUROIMAGE

Assessment of ischemic penumbra in patients with hyperacute stroke using amide proton transfer (APT) chemical exchange saturation transfer (CEST) MRI

(2013) Anna Tietze et al.   NMR IN BIOMEDICINE

Mapping glutamate in subcortical brain structures using high-resolution GluCEST MRI

(2013) Kejia Cai et al.   NMR IN BIOMEDICINE

Molecular imaging of tumors and metastases using chemical exchange saturation transfer (CEST) MRI

(2013) Michal Rivlin et al.   Scientific Reports

A Simple Model for Understanding the Origin of the Amide Proton Transfer MRI Signal in Tissue

(2012) Jinyuan Zhou et al.   APPLIED MAGNETIC RESONANCE

Improved pH measurements with a single PARACEST MRI contrast agent

(2012) Vipul R. Sheth et al.   Contrast Media & Molecular Imaging

7 tesla imaging of cerebral radiation necrosis after arteriovenous malformations treatment using amide proton transfer (APT) imaging

(2012) Lars Gerigk et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

Keyhole chemical exchange saturation transfer

(2012) G. Varma et al.   MAGNETIC RESONANCE IN MEDICINE

A new method for detecting exchanging amide protons using chemical exchange rotation transfer

(2012) Zhongliang Zu et al.   MAGNETIC RESONANCE IN MEDICINE

NaturalD-glucose as a biodegradable MRI contrast agent for detecting cancer

(2012) Kannie W. Y. Chan et al.   MAGNETIC RESONANCE IN MEDICINE

Magnetic resonance imaging of glutamate

(2012) Kejia Cai et al.   NATURE MEDICINE

Practical Dynamic Contrast Enhanced MRI in Small Animal Models of Cancer: Data Acquisition, Data Analysis, and Interpretation

(2012) Stephanie L. Barnes et al.   Pharmaceutics

Association between pH-Weighted Endogenous Amide Proton Chemical Exchange Saturation Transfer MRI and Tissue Lactic Acidosis during Acute Ischemic Stroke

(2011) Phillip Zhe Sun et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Chemical exchange saturation transfer magnetic resonance imaging of human knee cartilage at 3 T and 7 T

(2011) Anup Singh et al.   MAGNETIC RESONANCE IN MEDICINE

Simulation and optimization of pulsed radio frequency irradiation scheme for chemical exchange saturation transfer (CEST) MRI-demonstration of pH-weighted pulsed-amide proton CEST MRI in an animal model of acute cerebral ischemia

(2011) Phillip Zhe Sun et al.   MAGNETIC RESONANCE IN MEDICINE

Saturation power dependence of amide proton transfer image contrasts in human brain tumors and strokes at 3 T

(2011) Xuna Zhao et al.   MAGNETIC RESONANCE IN MEDICINE

Amide proton transfer imaging with improved robustness to magnetic field inhomogeneity and magnetization transfer asymmetry using saturation with frequency alternating RF irradiation

(2011) Rachel Scheidegger et al.   MAGNETIC RESONANCE IN MEDICINE

Chemical exchange saturation transfer (CEST): What is in a name and what isn't?

(2011) Peter C. M. van Zijl et al.   MAGNETIC RESONANCE IN MEDICINE

Development of chemical exchange saturation transfer at 7T

(2011) Adrienne N. Dula et al.   MAGNETIC RESONANCE IN MEDICINE

Measuring in vivo tumor pHe with CEST-FISP MRI

(2011) Vipul R. Sheth et al.   MAGNETIC RESONANCE IN MEDICINE

Assessment of glycosaminoglycan distribution in human lumbar intervertebral discs using chemical exchange saturation transfer at 3 T: feasibility and initial experience

(2011) Mina Kim et al.   NMR IN BIOMEDICINE

Cartilage Quality Assessment by Using Glycosaminoglycan Chemical Exchange Saturation Transfer and23Na MR Imaging at 7 T

(2011) Benjamin Schmitt et al.   RADIOLOGY

A New Contrast in MR Mammography by Means of Chemical Exchange Saturation Transfer (CEST) Imaging at 3 Tesla: Preliminary Results

(2011) B. Schmitt et al.   ROFO-FORTSCHRITTE AUF DEM GEBIET DER RONTGENSTRAHLEN UND DER BILDGEBENDEN VERFAHREN

CMR2009: 11.02: Evaluating iopamidol as pH-responsive CEST agent at 3 and 7 T

(2010) D. Longo et al.   Contrast Media & Molecular Imaging

Numerical solutions to the time-dependent Bloch equations revisited

(2010) Kenya Murase et al.   MAGNETIC RESONANCE IMAGING

Spin-locking versus chemical exchange saturation transfer MRI for investigating chemical exchange process between water and labile metabolite protons

(2010) Tao Jin et al.   MAGNETIC RESONANCE IN MEDICINE

Fast multislice pH-weighted chemical exchange saturation transfer (CEST) MRI with Unevenly segmented RF irradiation

(2010) Phillip Zhe Sun et al.   MAGNETIC RESONANCE IN MEDICINE

Iopamidol as a responsive MRI-chemical exchange saturation transfer contrast agent for pH mapping of kidneys: In vivo studies in mice at 7 T

(2010) Dario Livio Longo et al.   MAGNETIC RESONANCE IN MEDICINE

Differentiation between glioma and radiation necrosis using molecular magnetic resonance imaging of endogenous proteins and peptides

(2010) Jinyuan Zhou et al.   NATURE MEDICINE

MR imaging of high-grade brain tumors using endogenous protein and peptide-based contrast

(2010) Zhibo Wen et al.   NEUROIMAGE

A Review of Imaging Agent Development

(2009) Eric D. Agdeppa et al.   AAPS Journal

Water saturation shift referencing (WASSR) for chemical exchange saturation transfer (CEST) experiments

(2009) Mina Kim et al.   MAGNETIC RESONANCE IN MEDICINE

PARACEST MRI with improved temporal resolution

(2009) Guanshu Liu et al.   MAGNETIC RESONANCE IN MEDICINE

Four-pool modeling of proton exchange processes in biological systems in the presence of MRI-paramagnetic chemical exchange saturation transfer (PARACEST) agents

(2008) Alex X. Li et al.   MAGNETIC RESONANCE IN MEDICINE

Practical data acquisition method for human brain tumor amide proton transfer (APT) imaging

(2008) Jinyuan Zhou et al.   MAGNETIC RESONANCE IN MEDICINE

Assessment of glycosaminoglycan concentration in vivo by chemical exchange-dependent saturation transfer (gagCEST)

(2008) W. Ling et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An overview of responsive MRI contrast agents for molecular imaging

(2007) Byunghee Yoo   Frontiers in Bioscience-Landmark