What does the distribution of fitness effects of new mutations reflect? Insights from plants

Reconstructing the History of Variation in Effective Population Size along Phylogenies

(2021) Mathieu Brevet et al.   Genome Biology and Evolution

Hunting for beneficial mutations: conditioning on SIFT scores when estimating the distribution of fitness effect of new mutations

(2021) J Chen et al.   Genome Biology and Evolution

Inferring Genome-Wide Correlations of Mutation Fitness Effects between Populations

(2021) Xin Huang et al.   MOLECULAR BIOLOGY AND EVOLUTION

From Drift to Draft: How Much Do Beneficial Mutations Actually Contribute to Predictions of Ohta's Slightly Deleterious Model of Molecular Evolution?

(2020) Jun Chen et al.   GENETICS

Biased Gene Conversion Constrains Adaptation in Arabidopsis thaliana

(2020) Tuomas Hämälä et al.   GENETICS

Survival in the Tropics despite isolation, inbreeding and asexual reproduction: insights from the genome of the world’s southernmost poplar ( Populus ilicifolia )

(2020) Zeyuan Chen et al.   PLANT JOURNAL

Evolution of the mutation rate across primates

(2020) Manjusha Chintalapati et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Dioecy is associated with high genetic diversity and adaptation rates in the plant genus Silene

(2020) Aline Muyle et al.   MOLECULAR BIOLOGY AND EVOLUTION

Evolutionary rate and genetic load in an emblematic Mediterranean tree following an ancient and prolonged population collapse

(2020) Juan P. Jaramillo‐Correa et al.   MOLECULAR ECOLOGY

polyDFEv2.0: Testing for invariance of the distribution of fitness effects within and across species

(2019) Paula Tataru et al.   BIOINFORMATICS

Deleterious Mutation Burden and its Association with Complex Traits in Sorghum (Sorghum bicolor)

(2019) Ravi Valluru et al.   GENETICS

Parental legacy, demography, and admixture influenced the evolution of the two subgenomes of the tetraploid Capsella bursa-pastoris (Brassicaceae)

(2019) Dmytro Kryvokhyzha et al.   PLoS Genetics

Estimation of allele-specific fitness effects across human protein-coding sequences and implications for disease

(2019) Yi-Fei Huang et al.   GENOME RESEARCH

Inferring the distribution of fitness effects of spontaneous mutations in Chlamydomonas reinhardtii

(2019) Katharina B. Böndel et al.   PLOS BIOLOGY

Comparison of the Full Distribution of Fitness Effects of New Amino Acid Mutations Across Great Apes

(2019) David Castellano et al.   GENETICS

Variation of the adaptive substitution rate between species and within genomes

(2019) Ana Filipa Moutinho et al.   EVOLUTIONARY ECOLOGY

Inferring the Probability of the Derivedversusthe Ancestral Allelic State at a Polymorphic Site

(2018) Peter D. Keightley et al.   GENETICS

The Neutral Theory in Light of Natural Selection

(2018) Andrew D Kern et al.   MOLECULAR BIOLOGY AND EVOLUTION

Demography and mating system shape the genome-wide impact of purifying selection inArabis alpina

(2018) Benjamin Laenen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inferring the Probability of the Derivedversusthe Ancestral Allelic State at a Polymorphic Site

(2018) Peter D. Keightley et al.   GENETICS

The importance of the Neutral Theory in 1968 and 50 years on: A response to Kern and Hahn 2018

(2018) Jeffrey D. Jensen et al.   EVOLUTION

Inference of Distribution of Fitness Effects and Proportion of Adaptive Substitutions from Polymorphism Data

(2017) Paula Tataru et al.   GENETICS

Genetic Diversity and the Efficacy of Purifying Selection across Plant and Animal Species

(2017) Jun Chen et al.   MOLECULAR BIOLOGY AND EVOLUTION

The sources of adaptive variation

(2017) Deborah Charlesworth et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Inference of Distribution of Fitness Effects and Proportion of Adaptive Substitutions from Polymorphism Data

(2017) Paula Tataru et al.   GENETICS

The Limits of Natural Selection in a Nonequilibrium World

(2016) Yaniv Brandvain et al.   TRENDS IN GENETICS

Human Germline Mutation and the Erratic Evolutionary Clock

(2016) Priya Moorjani et al.   PLOS BIOLOGY

Adaptive Protein Evolution in Animals and the Effective Population Size Hypothesis

(2016) Nicolas Galtier   PLoS Genetics

Hybrid origins and the earliest stages of diploidization in the highly successful recent polyploidCapsella bursa-pastoris

(2015) Gavin M. Douglas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effects of new mutations on fitness: insights from models and data

(2014) Thomas Bataillon et al.   Annals of the New York Academy of Sciences

Comparative population genomics in animals uncovers the determinants of genetic diversity

(2014) J. Romiguier et al.   NATURE

Joint analysis of demography and selection in population genetics: where do we stand and where could we go?

(2011) JUNRUI LI et al.   MOLECULAR ECOLOGY

Identifying a High Fraction of the Human Genome to be under Selective Constraint Using GERP++

(2010) Eugene V. Davydov et al.   PLoS Computational Biology