Vorinostat, a histone deacetylase inhibitor, ameliorates the sociability and cognitive memory in an Ash1L-deletion-induced ASD/ID mouse model

Loss of histone methyltransferase ASH1L in the developing mouse brain causes autistic-like behaviors

(2021) Yuen Gao et al.   Communications Biology

Large-Scale Exome Sequencing Study Implicates Both Developmental and Functional Changes in the Neurobiology of Autism

(2020) F. Kyle Satterstrom et al.   CELL

Autism spectrum disorder

(2020) Catherine Lord et al.   Nature Reviews Disease Primers

A chromosome 1q22 microdeletion including ASH1L is associated with intellectual disability in a Chinese family

(2020) Hui Xi et al.   Molecular Cytogenetics

High-throughput single-cell functional elucidation of neurodevelopmental disease–associated genes reveals convergent mechanisms altering neuronal differentiation

(2020) Matthew A. Lalli et al.   GENOME RESEARCH

Identification of common genetic risk variants for autism spectrum disorder

(2019) Jakob Grove et al.   NATURE GENETICS

Inherited and De Novo Genetic Risk for Autism Impacts Shared Networks

(2019) Elizabeth K. Ruzzo et al.   CELL

Histone Lysine Methylases and Demethylases in the Landscape of Human Developmental Disorders

(2018) Víctor Faundes et al.   AMERICAN JOURNAL OF HUMAN GENETICS

De novo loss-of-function variants of ASH1L are associated with an emergent neurodevelopmental disorder

(2018) Wei Shen et al.   European Journal of Medical Genetics

Targeted sequencing identifies 91 neurodevelopmental-disorder risk genes with autism and developmental-disability biases

(2017) Holly A F Stessman et al.   NATURE GENETICS

De novo genic mutations among a Chinese autism spectrum disorder cohort

(2016) Tianyun Wang et al.   Nature Communications

Vorinostat-An overview

(2015) AdityaKumar Bubna   INDIAN JOURNAL OF DERMATOLOGY

HDAC signaling in neuronal development and axon regeneration

(2014) Yongcheol Cho et al.   CURRENT OPINION IN NEUROBIOLOGY

Erasers of Histone Acetylation: The Histone Deacetylase Enzymes

(2014) E. Seto et al.   Cold Spring Harbor Perspectives in Biology

An epigenetic blockade of cognitive functions in the neurodegenerating brain

(2012) Johannes Gräff et al.   NATURE

Diagnostic Exome Sequencing in Persons with Severe Intellectual Disability

(2012) Joep de Ligt et al.   NEW ENGLAND JOURNAL OF MEDICINE

H3K36 Methylation Antagonizes PRC2-mediated H3K27 Methylation

(2011) Wen Yuan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HDAC3 Is a Critical Negative Regulator of Long-Term Memory Formation

(2011) S. C. McQuown et al.   JOURNAL OF NEUROSCIENCE

Trithorax group proteins: switching genes on and keeping them active

(2011) Bernd Schuettengruber et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Assessment of Social Interaction Behaviors

(2011) Oksana Kaidanovich-Beilin et al.   Jove-Journal of Visualized Experiments

Targeting the correct HDAC(s) to treat cognitive disorders

(2010) André Fischer et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

A Simple Composite Phenotype Scoring System for Evaluating Mouse Models of Cerebellar Ataxia

(2010) Stephan J. Guyenet et al.   Jove-Journal of Visualized Experiments

CBP-mediated acetylation of histone H3 lysine 27 antagonizes Drosophila Polycomb silencing

(2009) F. Tie et al.   DEVELOPMENT

HDAC2 negatively regulates memory formation and synaptic plasticity

(2009) Ji-Song Guan et al.   NATURE

Inhibitors of Class 1 Histone Deacetylases Reverse Contextual Memory Deficits in a Mouse Model of Alzheimer's Disease

(2009) Mark Kilgore et al.   NEUROPSYCHOPHARMACOLOGY

Epigenetic targets of HDAC inhibition in neurodegenerative and psychiatric disorders

(2008) T ABEL et al.   CURRENT OPINION IN PHARMACOLOGY

Object recognition analysis in mice using nose-point digital video tracking

(2007) T.S. Benice et al.   JOURNAL OF NEUROSCIENCE METHODS