Sensitive period-regulating genetic pathways and exposure to adversity shape risk for depression

A critical period of neuronal activity results in aberrant neurogenesis rewiring hippocampal circuitry in a mouse model of epilepsy

(2021) Zane R. Lybrand et al.   Nature Communications

Cross-disorder genetic analyses implicate dopaminergic signaling as a biological link between Attention-Deficit/Hyperactivity Disorder and obesity measures

(2020) Nina Roth Mota et al.   NEUROPSYCHOPHARMACOLOGY

Minimal phenotyping yields genome-wide association signals of low specificity for major depression

(2020) Na Cai et al.   NATURE GENETICS

A Critical Period for Prefrontal Network Configurations Underlying Psychiatric Disorders and Addiction

(2020) Ramon Guirado et al.   Frontiers in Behavioral Neuroscience

Stress impacts corticoamygdalar connectivity in an age-dependent manner

(2020) Daniela L. Uliana et al.   NEUROPSYCHOPHARMACOLOGY

Multivariate genome-wide analyses of the well-being spectrum

(2019) Bart M. L. Baselmans et al.   NATURE GENETICS

Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions

(2019) David M. Howard et al.   NATURE NEUROSCIENCE

Identification of common genetic risk variants for autism spectrum disorder

(2019) Jakob Grove et al.   NATURE GENETICS

Genome-wide association study identifies 30 loci associated with bipolar disorder

(2019) Eli A. Stahl et al.   NATURE GENETICS

The critical importance of basic animal research for neuropsychiatric disorders

(2019) Tracy L. Bale et al.   NEUROPSYCHOPHARMACOLOGY

The role of polygenic risk score gene-set analysis in the context of the omnigenic model of schizophrenia

(2019) Alexandros Rammos et al.   NEUROPSYCHOPHARMACOLOGY

The REDCap consortium: Building an international community of software platform partners

(2019) Paul A. Harris et al.   JOURNAL OF BIOMEDICAL INFORMATICS

Genetic analyses of diverse populations improves discovery for complex traits

(2019) Genevieve L. Wojcik et al.   NATURE

Association of Schizophrenia Risk With Disordered Niacin Metabolism in an Indian Genome-wide Association Study

(2019) Sathish Periyasamy et al.   JAMA Psychiatry

Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways

(2019) Max Lam et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression

(2019) Kylie P. Glanville et al.   BIOLOGICAL PSYCHIATRY

Meta-analysis: Exposure to Early Life Stress and Risk for Depression in Childhood and Adolescence

(2019) Joelle LeMoult et al.   JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY

Genetic architecture of subcortical brain structures in 38,851 individuals

(2019) Claudia L. Satizabal et al.   NATURE GENETICS

Maturation of PNN and ErbB4 Signaling in Area CA2 during Adolescence Underlies the Emergence of PV Interneuron Plasticity and Social Memory

(2019) Soledad Domínguez et al.   Cell Reports

Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways

(2018) Mats Nagel et al.   NATURE GENETICS

Methylation in OTX2 and related genes, maltreatment, and depression in children

(2018) Joan Kaufman et al.   NEUROPSYCHOPHARMACOLOGY

What life course theoretical models best explain the relationship between exposure to childhood adversity and psychopathology symptoms: recency, accumulation, or sensitive periods?

(2018) Erin C. Dunn et al.   PSYCHOLOGICAL MEDICINE

Genome-wide meta-analyses of stratified depression in Generation Scotland and UK Biobank

(2018) Lynsey S. Hall et al.   Translational Psychiatry

Amygdala hyper-connectivity in a mouse model of unpredictable early life stress

(2018) Frances K. Johnson et al.   Translational Psychiatry

OUP accepted manuscript

(2018)   SCHIZOPHRENIA BULLETIN

Financial difficulties in childhood and adult depression in Europe

(2017) Tormod Bøe et al.   EUROPEAN JOURNAL OF PUBLIC HEALTH

Social Origins of Developmental Risk for Mental and Physical Illness

(2017) Judy L. Cameron et al.   JOURNAL OF NEUROSCIENCE

Is developmental timing of trauma exposure associated with depressive and post-traumatic stress disorder symptoms in adulthood?

(2017) Erin C. Dunn et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Genetic Otx2 mis-localization delays critical period plasticity across brain regions

(2017) H H C Lee et al.   MOLECULAR PSYCHIATRY

Genome-wide association analysis identifies 30 new susceptibility loci for schizophrenia

(2017) Zhiqiang Li et al.   NATURE GENETICS

Early life stress confers lifelong stress susceptibility in mice via ventral tegmental area OTX2

(2017) Catherine J. Peña et al.   SCIENCE

Etiology in psychiatry: embracing the reality of poly-gene-environmental causation of mental illness

(2017) Rudolf Uher et al.   World Psychiatry

Racial Disparities in Child Adversity in the U.S.

(2016) Natalie Slopen et al.   AMERICAN JOURNAL OF PREVENTIVE MEDICINE

GENOME-WIDE ASSOCIATION STUDY (GWAS) AND GENOME-WIDE BY ENVIRONMENT INTERACTION STUDY (GWEIS) OF DEPRESSIVE SYMPTOMS IN AFRICAN AMERICAN AND HISPANIC/LATINA WOMEN

(2016) Erin C. Dunn et al.   DEPRESSION AND ANXIETY

Racial/Ethnic Differences in the Role of Childhood Adversities for Mental Disorders Among a Nationally Representative Sample of Adolescents

(2016) Jennifer Ahern et al.   EPIDEMIOLOGY

Common variants on 2p16.1, 6p22.1 and 10q24.32 are associated with schizophrenia in Han Chinese population

(2016) H Yu et al.   MOLECULAR PSYCHIATRY

The Cellular and Molecular Landscapes of the Developing Human Central Nervous System

(2016) John C. Silbereis et al.   NEURON

Developmental and cross-modal plasticity in deafness: Evidence from the P1 and N1 event related potentials in cochlear implanted children

(2015) Anu Sharma et al.   INTERNATIONAL JOURNAL OF PSYCHOPHYSIOLOGY

Basomedial amygdala mediates top-down control of anxiety and fear

(2015) Avishek Adhikari et al.   NATURE

Is depression associated with increased oxidative stress? A systematic review and meta-analysis

(2015) Catherine N. Black et al.   PSYCHONEUROENDOCRINOLOGY

Targeting Oxidative Stress and Aberrant Critical Period Plasticity in the Developmental Trajectory to Schizophrenia

(2015) Kim Q. Do et al.   SCHIZOPHRENIA BULLETIN

Genetic Determinants of Depression

(2015) Erin C. Dunn et al.   HARVARD REVIEW OF PSYCHIATRY

MAGMA: Generalized Gene-Set Analysis of GWAS Data

(2015) Christiaan A. de Leeuw et al.   PLoS Computational Biology

A Meta-Analysis of Oxidative Stress Markers in Depression

(2015) Tao Liu et al.   PLoS One

Preliminary Evidence for Sensitive Periods in the Effect of Childhood Sexual Abuse on Regional Brain Development

(2014) Susan L. Andersen et al.   JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES

STAT1 Regulates the Homeostatic Component of Visual Cortical Plasticity via an AMPA Receptor-Mediated Mechanism

(2014) I. Nagakura et al.   JOURNAL OF NEUROSCIENCE

Sensitive Periods in Affective Development: Nonlinear Maturation of Fear Learning

(2014) Catherine A Hartley et al.   NEUROPSYCHOPHARMACOLOGY

A Note on an Exon-Based Strategy to Identify Differentially Expressed Genes in RNA-Seq Experiments

(2014) Asta Laiho et al.   PLoS One

Nonlinear developmental trajectory of fear learning and memory

(2013) Elizabeth C. King et al.   Annals of the New York Academy of Sciences

Spatial and Temporal Mapping of De Novo Mutations in Schizophrenia to a Fetal Prefrontal Cortical Network

(2013) Suleyman Gulsuner et al.   CELL

Cumulative Adversity in Childhood and Emergent Risk Factors for Long-Term Health

(2013) Natalie Slopen et al.   JOURNAL OF PEDIATRICS

Manipulation of BDNF Signaling Modifies the Experience-Dependent Plasticity Induced by Pure Tone Exposure during the Critical Period in the Primary Auditory Cortex

(2013) Renata Anomal et al.   PLoS One

Cumulative Neighborhood Risk of Psychosocial Stress and Allostatic Load in Adolescents

(2012) Katherine P. Theall et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Cohort Profile: The Avon Longitudinal Study of Parents and Children: ALSPAC mothers cohort

(2012) A. Fraser et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Cohort Profile: The ‘Children of the 90s’—the index offspring of the Avon Longitudinal Study of Parents and Children

(2012) Andy Boyd et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Critical period for acoustic preference in mice

(2012) E.-J. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Childhood maltreatment is associated with reduced volume in the hippocampal subfields CA3, dentate gyrus, and subiculum

(2012) M. H. Teicher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Childhood adversity and immune and inflammatory biomarkers associated with cardiovascular risk in youth: A systematic review

(2011) Natalie Slopen et al.   BRAIN BEHAVIOR AND IMMUNITY

Current research trends in early life stress and depression: Review of human studies on sensitive periods, gene–environment interactions, and epigenetics

(2011) Christine Heim et al.   EXPERIMENTAL NEUROLOGY

Research Review: Gene-environment interaction research in youth depression - a systematic review with recommendations for future research

(2011) Erin C. Dunn et al.   JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY

Telomere length and early severe social deprivation: linking early adversity and cellular aging

(2011) S S Drury et al.   MOLECULAR PSYCHIATRY

Spatio-temporal transcriptome of the human brain

(2011) Hyo Jung Kang et al.   NATURE

Childhood socio-economic status and the onset, persistence, and severity of DSM-IV mental disorders in a US national sample

(2011) Katie A. McLaughlin et al.   SOCIAL SCIENCE & MEDICINE

Psychiatric Outcomes in Young Children with a History of Institutionalization

(2011) Karen Bos et al.   HARVARD REVIEW OF PSYCHIATRY

The GABAergic deficit hypothesis of major depressive disorder

(2010) B Luscher et al.   MOLECULAR PSYCHIATRY

Analysing biological pathways in genome-wide association studies

(2010) Kai Wang et al.   NATURE REVIEWS GENETICS

Dissociable Roles of Prelimbic and Infralimbic Cortices, Ventral Hippocampus and Basolateral Amygdala in the Expression and Extinction of Conditioned Fear

(2010) Demetrio Sierra-Mercado et al.   NEUROPSYCHOPHARMACOLOGY

Effects of stress throughout the lifespan on the brain, behaviour and cognition

(2009) Sonia J. Lupien et al.   NATURE REVIEWS NEUROSCIENCE

Perineuronal Nets Protect Fear Memories from Erasure

(2009) N. Gogolla et al.   SCIENCE

Research electronic data capture (REDCap)—A metadata-driven methodology and workflow process for providing translational research informatics support

(2008) Paul A. Harris et al.   JOURNAL OF BIOMEDICAL INFORMATICS

Burden and consequences of child maltreatment in high-income countries

(2008) Ruth Gilbert et al.   LANCET

Tumor Necrosis Factor-α Mediates One Component of Competitive, Experience-Dependent Plasticity in Developing Visual Cortex

(2008) Megumi Kaneko et al.   NEURON

Molecular mechanisms of experience-dependent plasticity in visual cortex

(2008) D. Tropea et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES